Evaluation of Salivary Biomarkers and Their Correlation to Periodontal Status and BMI

Tarza J. Mahmood; Faraedon M. Zardawi1

Article Details

Evaluation of Salivary Biomarkers and Their Correlation to Periodontal Status and BMI

Authors:

Tarza J. Mahmood | Faraedon M. Zardawi1

Publisher:

University of Sulaimani

Journal:

Sulaimani Dental Journal Vol.7 Issue 2, pp.16-24

Document Type:

Article

Publication Date:

2/2025

Document Language:

English

Document ID (Org No.):

2001932945

pISSN:

2309-4656

Keywords:

Abstract:

 Objective: This study aimed to determine the correlation between periodontal status and BMI by evaluating salivary biomarkers - Resistin, visfatin, and TNF-α.           Methods: Among 580 screened subjects, 86 subjects (30 male and 56 female) aged 30-60 years recruited and grouped into four groups, Group 1 – non-obese with healthy periodontium, group 2 – non-obese with periodontitis, group 3 - obese with healthy periodontium, and group 4 - obese with periodontitis, according to their clinical periodontal parameters and BMI. (ELISA) was used to measure the salivary concentration of Resistin, Visfatin, and TNF-α. (SPSS, v.20.0) applied for statistical analysis, Shapiro-Wilk used to test the Normality of distribution. One-way ANOVA and Mann-Whitney U test were used to analyze the outcome data. Results: Significant differences in the clinical variables (PI, BI, PPD, and CAL) between test and control groups, with and with no periodontitis (P 0.05) between the level of Resistin were detected in the four groups tested. TNF-α was and periodontitis obese groups (P-value< 0.05). No significant correlations were found between clinical periodontal parameters and BMI and the three biomarkers' levels in the four groups tested in this study. Conclusions: The study failed to detect significant positive correlations between the salivary biomarkers' levels and clinical periodontal and obesity parameters.

Article Details

Evaluation of Salivary Biomarkers and Their Correlation to Periodontal Status and BMI

Authors:

Tarza J. Mahmood | Faraedon M. Zardawi1

Publisher:

University of Sulaimani

Journal:

Sulaimani Dental Journal Vol.7 Issue 2, pp.16-24

Document Type:

Article

Publication Date:

2/2025

Document Language:

English

Document ID (Org No.):

2001932945

pISSN:

2309-4656

BMI

Obesity

Periodontitis

Salivary biomarker

Issues

Article Details

Evaluation of Salivary Biomarkers and Their Correlation to Periodontal Status and BMI

Authors: Tarza J. Mahmood | Faraedon M. Zardawi1

Publisher: University of Sulaimani

Journal: Sulaimani Dental Journal Vol.7 Issue 2, pp.16-24

Document Type: Article

Publication Date: 2/2025

Document Language: English

Document ID (Org No.): 2001932945

pISSN: 2309-4656

BMI

Obesity

Periodontitis

Salivary biomarker

Issues

Authors:

Tarza J. Mahmood | Faraedon M. Zardawi1

Publisher:

University of Sulaimani

Journal:

Sulaimani Dental Journal Vol.7 Issue 2, pp.16-24

Document Type:

Article

Publication Date:

2/2025

Document Language:

English

Document ID (Org No.):

2001932945

pISSN:

2309-4656