In Vivo Immunohistochemical Investigation of Bone Deposition at Amelogenin Coated Ti Implant Surface

Bushra Habeeb Al-Molla; Nada Al-Ghaban; Abbas Taher

doi:10.12816/0008316

Article Details

In Vivo Immunohistochemical Investigation of Bone Deposition at Amelogenin Coated Ti Implant Surface

Authors:

Bushra Habeeb Al-Molla | Nada Al-Ghaban | Abbas Taher

Publisher:

MENA Co. for Dental Services

Main Topics:

Medicine

Journal:

Smile Dental Journal 2014 Vol.9 Issue 1, pp.12-17

Document Type:

Article

Publication Date:

3/2014

Document Language:

English

Document ID (Org No.):

56388

Frequency:

Quarterly

eISSN:

20724748

pISSN:

2072473X

DOI:

10.12816/0008316

Descriptors:

Keywords:

Abstract:

 Background: Dental implant is an artificial tooth root fixed into the jaws to hold a replacement tooth or bridge.Functional surface modifications by organic material such as amelogenin coating seem to enhance early peri-implantbone formation. The aim of the study was to study the expression of osteocalcin and collagen I as bone formationmarkers in amelogenin coated and uncoated implant in interval periods (1,2,4 and 6 weeks).Materials and Methods: Commercially pure Titanium (cpTi) implants, coated with amelogenin protein, were placed inthe tibias of 40 New Zealand white rabbits, histological and immunohistochemical tests for detection of expression ofosteocalcin and collagen I were performed on all the implants of both control and experimental groups for (1,2,4 and6 weeks) healing intervals.Results: Histological finding for coated titanium implant with amelogenin illustrated an early bone formation,mineralization and maturation in comparison to control.Immunohistochemical finding showed that positive reaction for osteocalcin and collagen I was expressed by osteoblastcells (OB) at implants coated with amelogenin, indicating that bone formation &maturation was accelerated byadding biological materials as a modification modality of implant surface.Conclusion: The present study concludes that coating of implants with amelogenin showed increment inosseointegration in short interval period.

Article Details

In Vivo Immunohistochemical Investigation of Bone Deposition at Amelogenin Coated Ti Implant Surface

Authors:

Bushra Habeeb Al-Molla | Nada Al-Ghaban | Abbas Taher

Publisher:

MENA Co. for Dental Services

Main Topics:

Medicine

Journal:

Smile Dental Journal 2014 Vol.9 Issue 1, pp.12-17

Document Type:

Article

Publication Date:

3/2014

Document Language:

English

Document ID (Org No.):

56388

Frequency:

Quarterly

eISSN:

20724748

pISSN:

2072473X

DOI:

10.12816/0008316

Descriptors:

DENTISTRY

PROSTHESIS

DENTAL PROSTHESIS

BIOCHEMICAL COMPOSITION

COLLAGEN

PATIENTS

DENTISTS

Amelogenin

Dental Implant

Biochemical Bone Markers

Osteocalcin

Collagen I

Osseointegration

Issues

Article Details

Authors: Bushra Habeeb Al-Molla | Nada Al-Ghaban | Abbas Taher

Publisher: MENA Co. for Dental Services

Main Topics: Medicine

Journal: Smile Dental Journal 2014 Vol.9 Issue 1, pp.12-17

Document Type: Article

Publication Date: 3/2014

Document Language: English

Document ID (Org No.): 56388

Frequency: Quarterly

eISSN: 20724748

pISSN: 2072473X

DOI: 10.12816/0008316

Descriptors:

Issues

Authors:

Bushra Habeeb Al-Molla | Nada Al-Ghaban | Abbas Taher

Publisher:

MENA Co. for Dental Services

Main Topics:

Medicine

Journal:

Smile Dental Journal 2014 Vol.9 Issue 1, pp.12-17

Document Type:

Article

Publication Date:

3/2014

Document Language:

English

Document ID (Org No.):

56388

Frequency:

Quarterly

eISSN:

20724748

pISSN:

2072473X

DOI:

10.12816/0008316