The neutrophil-lymphocyte ratio and its relationship with insulin resistance in obesity

Serdar KARAKAYA; Mustafa ALTAY; Fatma Kaplan EFE; İbrahim KARADAĞ; Oktay ÜNSAL; Oktay BULUR; MURAT ESER; Derun Taner ERTUĞRUL

Article Details

The neutrophil-lymphocyte ratio and its relationship with insulin resistance in obesity

Authors:

Serdar KARAKAYA | Mustafa ALTAY | Fatma Kaplan EFE | İbrahim KARADAĞ | Oktay ÜNSAL | Oktay BULUR | MURAT ESER | Derun Taner ERTUĞRUL

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 1, pp.245-248

Document Type:

Article

Publication Date:

1/2019

Document Language:

Turkish

Document ID (Org No.):

2000750345

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

In this study, our aim was to investigate the neutrophil/lymphocyte (N/L) ratio, variations in leukocytes and leukocyte subtypes, and the relationship between N/L ratio and insulin resistance (IR) in obesity.Materials and methods: Ninety-six patients and 40 healthy controls were included in this study. Patients' blood glucose levels, insulin levels, and hemogram parameters upon 8 h of fasting were determined. Body mass index (BMI) and Homeostasis Model Assessment-Insulin Resistance (HOMA-IR) values were calculated.Results: Neutrophil numbers were found to be higher among obese patients with IR than among non-IR obese patients. The N/L ratio was, moreover, found to be higher among obese patients with IR when compared to non-IR obese patients. A positive correlation was found between insulin resistance and both neutrophil and WBC counts. Positive correlations were also found between insulin levels and the N/L ratio, WBC counts, and neutrophil counts.Conclusion: In our study, leukocyte numbers and subtypes were determined to be higher among obese individuals than among healthy individuals. The N/L ratio was increased significantly only among obese patients with IR. Further studies are needed in order to better demonstrate the relationship between the N/L ratio and IR/inflammation.

Article Details

The neutrophil-lymphocyte ratio and its relationship with insulin resistance in obesity

Authors: Serdar KARAKAYA | Mustafa ALTAY | Fatma Kaplan EFE | İbrahim KARADAĞ | Oktay ÜNSAL | Oktay BULUR | MURAT ESER | Derun Taner ERTUĞRUL

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 1, pp.245-248

Document Type: Article

Publication Date: 1/2019

Document Language: Turkish

Document ID (Org No.): 2000750345

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Serdar KARAKAYA | Mustafa ALTAY | Fatma Kaplan EFE | İbrahim KARADAĞ | Oktay ÜNSAL | Oktay BULUR | MURAT ESER | Derun Taner ERTUĞRUL

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 1, pp.245-248

Document Type:

Article

Publication Date:

1/2019

Document Language:

Turkish

Document ID (Org No.):

2000750345

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144