The effect of scaling and root planing on salivary cortisol levels in patients with moderate chronic periodontitis

Sohrab Halalkhor; Mozhgan Abootalebzadeh; Majid Fereidooni; Nahid Neamati

Article Details

The effect of scaling and root planing on salivary cortisol levels in patients with moderate chronic periodontitis

Authors:

Sohrab Halalkhor | Mozhgan Abootalebzadeh | Majid Fereidooni | Nahid Neamati

Publisher:

Ondokuz Mayıs University

Main Topics:

Medical Biochemistry - Proteins | Peptides and Proteomics

Journal:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 2, pp.253-258

Document Type:

Article

Publication Date:

5/2024

Document Language:

English

Document ID (Org No.):

2001317643

pISSN:

1309-4483

Keywords:

Abstract:

 Periodontitis is known as one of the most prevalent inflammatory oral diseases. Glucocorticoid hormones such as cortisol, produced by the hypothalamuspituitaryadrenal axis can influence all processes and tissues in human body homeostasis. Typically, the glucocorticoids have been regarded as anti-inflammatory substances and have pro-inflammatory effect in the body. The aim of this study was to evaluate the effect of non-surgical periodontal treatment NPT on cortisol levels in patients with moderate chronic periodontitis MCP. Saliva samples were collected from 42 participants with MCP before and two months after scaling and root planing SRP. Salivary cortisol levels SCLs were measured by electrochemiluminescence immunoassay method. The relationship between clinical periodontal parameters such as gingival index GI and probing pocket depth PPD with cortisol levels was assessed and analyzed by statistical analysis. was statistically analyzed The SCLs were significantly lower after treatment than before treatment p0.02. The GI and PPD showed significant differences p0.001, p0.001, respectively. There was a positive relationship between these periodontal parameters and cortisol levels, the correlation between GI and cortisol levels was not statistically significant p  0.19 and there was a borderline significant correlation between PPD and SCLs p  0.06. In the present study, the SCLs were related to NPT. The treatment improved clinical periodontal parameters.

 Periodontitis is known as one of the most prevalent inflammatory oral diseases. Glucocorticoid hormones such as cortisol, produced by the hypothalamuspituitaryadrenal axis can influence all processes and tissues in human body homeostasis. Typically, the glucocorticoids have been regarded as anti-inflammatory substances and have pro-inflammatory effect in the body. The aim of this study was to evaluate the effect of non-surgical periodontal treatment NPT on cortisol levels in patients with moderate chronic periodontitis MCP. Saliva samples were collected from 42 participants with MCP before and two months after scaling and root planing SRP. Salivary cortisol levels SCLs were measured by electrochemiluminescence immunoassay method. The relationship between clinical periodontal parameters such as gingival index GI and probing pocket depth PPD with cortisol levels was assessed and analyzed by statistical analysis. was statistically analyzed The SCLs were significantly lower after treatment than before treatment p0.02. The GI and PPD showed significant differences p0.001, p0.001, respectively. There was a positive relationship between these periodontal parameters and cortisol levels, the correlation between GI and cortisol levels was not statistically significant p  0.19 and there was a borderline significant correlation between PPD and SCLs p  0.06. In the present study, the SCLs were related to NPT. The treatment improved clinical periodontal parameters.

 Periodontitis is known as one of the most prevalent inflammatory oral diseases. Glucocorticoid hormones such as cortisol, produced by the hypothalamuspituitaryadrenal axis can influence all processes and tissues in human body homeostasis. Typically, the glucocorticoids have been regarded as anti-inflammatory substances and have pro-inflammatory effect in the body. The aim of this study was to evaluate the effect of non-surgical periodontal treatment NPT on cortisol levels in patients with moderate chronic periodontitis MCP. Saliva samples were collected from 42 participants with MCP before and two months after scaling and root planing SRP. Salivary cortisol levels SCLs were measured by electrochemiluminescence immunoassay method. The relationship between clinical periodontal parameters such as gingival index GI and probing pocket depth PPD with cortisol levels was assessed and analyzed by statistical analysis. was statistically analyzed The SCLs were significantly lower after treatment than before treatment p0.02. The GI and PPD showed significant differences p0.001, p0.001, respectively. There was a positive relationship between these periodontal parameters and cortisol levels, the correlation between GI and cortisol levels was not statistically significant p  0.19 and there was a borderline significant correlation between PPD and SCLs p  0.06. In the present study, the SCLs were related to NPT. The treatment improved clinical periodontal parameters.

 Periodontitis is known as one of the most prevalent inflammatory oral diseases. Glucocorticoid hormones such as cortisol, produced by the hypothalamuspituitaryadrenal axis can influence all processes and tissues in human body homeostasis. Typically, the glucocorticoids have been regarded as anti-inflammatory substances and have pro-inflammatory effect in the body. The aim of this study was to evaluate the effect of non-surgical periodontal treatment NPT on cortisol levels in patients with moderate chronic periodontitis MCP. Saliva samples were collected from 42 participants with MCP before and two months after scaling and root planing SRP. Salivary cortisol levels SCLs were measured by electrochemiluminescence immunoassay method. The relationship between clinical periodontal parameters such as gingival index GI and probing pocket depth PPD with cortisol levels was assessed and analyzed by statistical analysis. was statistically analyzed The SCLs were significantly lower after treatment than before treatment p0.02. The GI and PPD showed significant differences p0.001, p0.001, respectively. There was a positive relationship between these periodontal parameters and cortisol levels, the correlation between GI and cortisol levels was not statistically significant p  0.19 and there was a borderline significant correlation between PPD and SCLs p  0.06. In the present study, the SCLs were related to NPT. The treatment improved clinical periodontal parameters.

Article Details

The effect of scaling and root planing on salivary cortisol levels in patients with moderate chronic periodontitis

Authors:

Sohrab Halalkhor | Mozhgan Abootalebzadeh | Majid Fereidooni | Nahid Neamati

Publisher:

Ondokuz Mayıs University

Main Topics:

Medical Biochemistry - Proteins | Peptides and Proteomics

Journal:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 2, pp.253-258

Document Type:

Article

Publication Date:

5/2024

Document Language:

English

Document ID (Org No.):

2001317643

pISSN:

1309-4483

Glucocorticoid

Cortisol

Scaling and root planing

Chronic periodontitis

Saliva

Issues

Article Details

The effect of scaling and root planing on salivary cortisol levels in patients with moderate chronic periodontitis

Authors: Sohrab Halalkhor | Mozhgan Abootalebzadeh | Majid Fereidooni | Nahid Neamati

Publisher: Ondokuz Mayıs University

Main Topics: Medical Biochemistry - Proteins | Peptides and Proteomics

Journal: Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 2, pp.253-258

Document Type: Article

Publication Date: 5/2024

Document Language: English

Document ID (Org No.): 2001317643

pISSN: 1309-4483

Glucocorticoid

Cortisol

Scaling and root planing

Chronic periodontitis

Saliva

Issues

Authors:

Sohrab Halalkhor | Mozhgan Abootalebzadeh | Majid Fereidooni | Nahid Neamati

Publisher:

Ondokuz Mayıs University

Main Topics:

Medical Biochemistry - Proteins | Peptides and Proteomics

Journal:

Deneysel ve Klinik Tıp Dergisi Vol.41 Issue 2, pp.253-258

Document Type:

Article

Publication Date:

5/2024

Document Language:

English

Document ID (Org No.):

2001317643

pISSN:

1309-4483