Comparison of Cardioplegia Given by Ready Cardioplegia Set and Liquid Set in Terms of Administration Time

Murat Ziya Bağış; Yasemin Hacanlı

Article Details

Comparison of Cardioplegia Given by Ready Cardioplegia Set and Liquid Set in Terms of Administration Time

Authors:

Murat Ziya Bağış | Yasemin Hacanlı

Publisher:

Harran University

Main Topics:

Kalp ve Damar Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 2, pp.239-244

Document Type:

Article

Publication Date:

6/2025

Document Language:

Turkish

Document ID (Org No.):

2001343942

pISSN:

1304-9623

Keywords:

Abstract:

 Background: We aimed to investigate the effect of cardioplegic solutions given with ready-made sets on the duration of administration compared to those given with liquid sets in patients undergoing open heart surgery with Cardiopulmonary Bypass in terms of postoperative morbidity and mortality. Materials and Methods: A total of 88 patients 59 males and 29 females over 18 years of age who un-derwent open heart surgery with cardiopulmonary bypass were retrospectively included in the study. The first 24 hours postoperative data of these patients were analyzed. Patients were divided into two groups according to cardioplegia administration sets. Group 1 n44: cardioplegia was administered with a prepared set, group 2 n44: cardioplegia was administered with a liquid set. Statistical analysis and comparison of the effect of cardioplegia administration times on total cross-clamp times and postoperati-ve lactate, urea, creatinine, potassium, CRP, WBC, urine levels, extubation, intensive care unit, hospitali-zation times and mortality were performed between the groups. Results: When the descriptive statistical data between the groups were analyzed, it was found that the postoperative lactate level was significantly lower p0.002, extubation time p0.001, intensive care unit stay p0.043, cross-clamp time p0.001 and total bypass time p0.001 were significantly shorter in the group using the ready-made set compared to the group using the liquid set. However, there was no significant difference in mortality between the groups p0.246. Conclusions: Although extubation time, intensive care unit stay, cross-clamping time and total bypass time were shorter in the group given cardioplegia with ready-made sets, it was found that ready-made and liquid sets had similar outcomes in terms of mortality.

 Background: We aimed to investigate the effect of cardioplegic solutions given with ready-made sets on the duration of administration compared to those given with liquid sets in patients undergoing open heart surgery with Cardiopulmonary Bypass in terms of postoperative morbidity and mortality. Materials and Methods: A total of 88 patients 59 males and 29 females over 18 years of age who un-derwent open heart surgery with cardiopulmonary bypass were retrospectively included in the study. The first 24 hours postoperative data of these patients were analyzed. Patients were divided into two groups according to cardioplegia administration sets. Group 1 n44: cardioplegia was administered with a prepared set, group 2 n44: cardioplegia was administered with a liquid set. Statistical analysis and comparison of the effect of cardioplegia administration times on total cross-clamp times and postoperati-ve lactate, urea, creatinine, potassium, CRP, WBC, urine levels, extubation, intensive care unit, hospitali-zation times and mortality were performed between the groups. Results: When the descriptive statistical data between the groups were analyzed, it was found that the postoperative lactate level was significantly lower p0.002, extubation time p0.001, intensive care unit stay p0.043, cross-clamp time p0.001 and total bypass time p0.001 were significantly shorter in the group using the ready-made set compared to the group using the liquid set. However, there was no significant difference in mortality between the groups p0.246. Conclusions: Although extubation time, intensive care unit stay, cross-clamping time and total bypass time were shorter in the group given cardioplegia with ready-made sets, it was found that ready-made and liquid sets had similar outcomes in terms of mortality.

 Background: We aimed to investigate the effect of cardioplegic solutions given with ready-made sets on the duration of administration compared to those given with liquid sets in patients undergoing open heart surgery with Cardiopulmonary Bypass in terms of postoperative morbidity and mortality. Materials and Methods: A total of 88 patients 59 males and 29 females over 18 years of age who un-derwent open heart surgery with cardiopulmonary bypass were retrospectively included in the study. The first 24 hours postoperative data of these patients were analyzed. Patients were divided into two groups according to cardioplegia administration sets. Group 1 n44: cardioplegia was administered with a prepared set, group 2 n44: cardioplegia was administered with a liquid set. Statistical analysis and comparison of the effect of cardioplegia administration times on total cross-clamp times and postoperati-ve lactate, urea, creatinine, potassium, CRP, WBC, urine levels, extubation, intensive care unit, hospitali-zation times and mortality were performed between the groups. Results: When the descriptive statistical data between the groups were analyzed, it was found that the postoperative lactate level was significantly lower p0.002, extubation time p0.001, intensive care unit stay p0.043, cross-clamp time p0.001 and total bypass time p0.001 were significantly shorter in the group using the ready-made set compared to the group using the liquid set. However, there was no significant difference in mortality between the groups p0.246. Conclusions: Although extubation time, intensive care unit stay, cross-clamping time and total bypass time were shorter in the group given cardioplegia with ready-made sets, it was found that ready-made and liquid sets had similar outcomes in terms of mortality.

 Amaç: Kardiyopulmoner Bypass eşliğinde açık kalp cerrahisi uygulanan hastalarda hazır setler ile verilen kardiyoplejik solüsyonların, sıvı setler ile verilenlere göre veriliş sürelerine etkisi incelenerek postoperatif morbidite ve mortalite yönünden araştırılmasını amaçladık. Materyal ve metod: Kardiyopulmoner baypas ile açık kalp ameliyatı geçiren 18 yaş üstü toplam 88 hasta 59 erkek ve 29 kadın retrospektif olarak çalışmaya dahil edildi. Bu hastalara ait ilk 24 saatlik postoperatif bilgiler incelendi. Hastalar kardiyopleji verilme setlerine göre iki gruba ayrıldı. Grup 1 n 44: hazır set ile kardiyopleji verilen grup, grup 2 n44: sıvı sette hazırlanarak kardiyopleji verilen grup. Gruplar arasında kardiyopleji veriliş sürelerinin toplam kros klemp sürelerine etkisi ve postoperatif laktat, üre, kreatinin, potasyum, CRP, WBC, idrar seviyeleri ile ekstübasyon, yoğun bakım, hastanede yatış süreleri ve mortalite-nin istatistiksel analizi ve karşılaştırmaları yapıldı. Bulgular: Gruplar arasında tanımlayıcı istatistik verileri incelendiğinde sıvı set kullanılan grup ile karşılaştı-rıldığında; hazır set kullanılan grupta postoperatif laktat düzeyinin anlamlı olarak daha düşük p0,002, ekstübasyon süresi p0,001, yoğun bakım ünitesinde kalış süresi p0,043, kros klemp süresi p0,001 ve total bypass süresinin de p0,001 anlamlı olarak daha kısa olduğu tespit edildi.Ancak, gruplar arasında mortalite açısından anlamlı bir farklılık olmadığı saptandı p0,246. Sonuç: Hazır set ile kardiyopleji verilen grupta ekstübasyon süresi, yoğun bakım ünitesinde kalış süresi, kros klemp süresi ve total bypass süresi daha kısa olsa da hazır setler ile sıvı setlerin mortalite açısından benzer sonlanımlara sahip olduğu saptandı.

Article Details

Comparison of Cardioplegia Given by Ready Cardioplegia Set and Liquid Set in Terms of Administration Time

Authors:

Murat Ziya Bağış | Yasemin Hacanlı

Publisher:

Harran University

Main Topics:

Kalp ve Damar Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 2, pp.239-244

Document Type:

Article

Publication Date:

6/2025

Document Language:

Turkish

Document ID (Org No.):

2001343942

pISSN:

1304-9623

Cardioplegia

Cardiopulmonary Bypass

Myocardial ProtectionKardiyopleji

Kardiyopulmoner Bypass

Miyokardiyal Koruma

Issues

Article Details

Comparison of Cardioplegia Given by Ready Cardioplegia Set and Liquid Set in Terms of Administration Time

Authors: Murat Ziya Bağış | Yasemin Hacanlı

Publisher: Harran University

Main Topics: Kalp ve Damar Cerrahisi

Journal: Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 2, pp.239-244

Document Type: Article

Publication Date: 6/2025

Document Language: Turkish

Document ID (Org No.): 2001343942

pISSN: 1304-9623

Cardioplegia

Cardiopulmonary Bypass

Myocardial ProtectionKardiyopleji

Kardiyopulmoner Bypass

Miyokardiyal Koruma

Issues

Authors:

Murat Ziya Bağış | Yasemin Hacanlı

Publisher:

Harran University

Main Topics:

Kalp ve Damar Cerrahisi

Journal:

Harran Üniversitesi Tıp Fakültesi Dergisi Vol.22 Issue 2, pp.239-244

Document Type:

Article

Publication Date:

6/2025

Document Language:

Turkish

Document ID (Org No.):

2001343942

pISSN:

1304-9623