Is there any effect of long term alpha-adrenergic blocker and a single dose antibiotic usage in reducing febrile urinary tract infections after prostate biopsy?

Kubilay Sarıkaya; Muhammed Arif İbiş

Article Details

Is there any effect of long term alpha-adrenergic blocker and a single dose antibiotic usage in reducing febrile urinary tract infections after prostate biopsy?

Authors:

Kubilay Sarıkaya | Muhammed Arif İbiş

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.1-6

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001282271

pISSN:

2636-8579

Keywords:

Abstract:

 Aim: To investigate whether the using long term alpha-adrenergic blockers before biopsy has an effect on preventing febrile urinary tract infections FUI secondary to biopsy in patients undergoing prostate biopsy due to elevated prostate specific antigen PSA . Material and Method: The data of 2558 patients who underwent transrectal ultrasonography-guided prostate biopsy TRUSBX due to elevated PSA in our clinic between January 2008 and July 2021 were analyzed retrospectively. The patients were divided into two groups as those who used alpha-blockers for a minimum of three months or longer before biopsy Group 1 and those who did not use alpha-blockers before applying to the outpatient clinic Group 2 . Demographic data of the groups and post-biopsy FUI development rates were compared. Results: It was observed that 1340 52.4 of the patients were using alpha-blockers Group 1 and 1218 47.6 did not Group 2 . The median age of the patients in the pre-biopsy groups was similar Group 168 IQR9 years and Group 268 IQR9 years, p0.887. There was no significant difference between the groups in terms of median prostate volume Group157 31 ml and Group 258 34 ml, p0.199. The median PSA value was found to be significantly higher in Group 1 than in Group 2 10.50 5.40 ngdl vs 10.35 6.80 ngdl, p0.026. Postvoid residual urine volume PVR was found to be significantly higher in Group 2 Group 140 30 ml and Group260 90 ml, p0.001. Similarly, the frequency of FUI development after biopsy was found to be significantly higher in Group 2 Group 117 1.3 and Group 265 5.3 , p0.001. Conclusion: The use of alpha-adrenergic blockers for a minimum of three months or longer before prostate biopsy significantly reduces the incidence of FUI that may develop secondary to biopsy.

 Aim: To investigate whether the using long term alpha-adrenergic blockers before biopsy has an effect on preventing febrile urinary tract infections FUI secondary to biopsy in patients undergoing prostate biopsy due to elevated prostate specific antigen PSA . Material and Method: The data of 2558 patients who underwent transrectal ultrasonography-guided prostate biopsy TRUSBX due to elevated PSA in our clinic between January 2008 and July 2021 were analyzed retrospectively. The patients were divided into two groups as those who used alpha-blockers for a minimum of three months or longer before biopsy Group 1 and those who did not use alpha-blockers before applying to the outpatient clinic Group 2 . Demographic data of the groups and post-biopsy FUI development rates were compared. Results: It was observed that 1340 52.4 of the patients were using alpha-blockers Group 1 and 1218 47.6 did not Group 2 . The median age of the patients in the pre-biopsy groups was similar Group 168 IQR9 years and Group 268 IQR9 years, p0.887. There was no significant difference between the groups in terms of median prostate volume Group157 31 ml and Group 258 34 ml, p0.199. The median PSA value was found to be significantly higher in Group 1 than in Group 2 10.50 5.40 ngdl vs 10.35 6.80 ngdl, p0.026. Postvoid residual urine volume PVR was found to be significantly higher in Group 2 Group 140 30 ml and Group260 90 ml, p0.001. Similarly, the frequency of FUI development after biopsy was found to be significantly higher in Group 2 Group 117 1.3 and Group 265 5.3 , p0.001. Conclusion: The use of alpha-adrenergic blockers for a minimum of three months or longer before prostate biopsy significantly reduces the incidence of FUI that may develop secondary to biopsy.

 Aim: To investigate whether the using long term alpha-adrenergic blockers before biopsy has an effect on preventing febrile urinary tract infections FUI secondary to biopsy in patients undergoing prostate biopsy due to elevated prostate specific antigen PSA . Material and Method: The data of 2558 patients who underwent transrectal ultrasonography-guided prostate biopsy TRUSBX due to elevated PSA in our clinic between January 2008 and July 2021 were analyzed retrospectively. The patients were divided into two groups as those who used alpha-blockers for a minimum of three months or longer before biopsy Group 1 and those who did not use alpha-blockers before applying to the outpatient clinic Group 2 . Demographic data of the groups and post-biopsy FUI development rates were compared. Results: It was observed that 1340 52.4 of the patients were using alpha-blockers Group 1 and 1218 47.6 did not Group 2 . The median age of the patients in the pre-biopsy groups was similar Group 168 IQR9 years and Group 268 IQR9 years, p0.887. There was no significant difference between the groups in terms of median prostate volume Group157 31 ml and Group 258 34 ml, p0.199. The median PSA value was found to be significantly higher in Group 1 than in Group 2 10.50 5.40 ngdl vs 10.35 6.80 ngdl, p0.026. Postvoid residual urine volume PVR was found to be significantly higher in Group 2 Group 140 30 ml and Group260 90 ml, p0.001. Similarly, the frequency of FUI development after biopsy was found to be significantly higher in Group 2 Group 117 1.3 and Group 265 5.3 , p0.001. Conclusion: The use of alpha-adrenergic blockers for a minimum of three months or longer before prostate biopsy significantly reduces the incidence of FUI that may develop secondary to biopsy.

 Aim: To investigate whether the using long term alpha-adrenergic blockers before biopsy has an effect on preventing febrile urinary tract infections FUI secondary to biopsy in patients undergoing prostate biopsy due to elevated prostate specific antigen PSA . Material and Method: The data of 2558 patients who underwent transrectal ultrasonography-guided prostate biopsy TRUSBX due to elevated PSA in our clinic between January 2008 and July 2021 were analyzed retrospectively. The patients were divided into two groups as those who used alpha-blockers for a minimum of three months or longer before biopsy Group 1 and those who did not use alpha-blockers before applying to the outpatient clinic Group 2 . Demographic data of the groups and post-biopsy FUI development rates were compared. Results: It was observed that 1340 52.4 of the patients were using alpha-blockers Group 1 and 1218 47.6 did not Group 2 . The median age of the patients in the pre-biopsy groups was similar Group 168 IQR9 years and Group 268 IQR9 years, p0.887. There was no significant difference between the groups in terms of median prostate volume Group157 31 ml and Group 258 34 ml, p0.199. The median PSA value was found to be significantly higher in Group 1 than in Group 2 10.50 5.40 ngdl vs 10.35 6.80 ngdl, p0.026. Postvoid residual urine volume PVR was found to be significantly higher in Group 2 Group 140 30 ml and Group260 90 ml, p0.001. Similarly, the frequency of FUI development after biopsy was found to be significantly higher in Group 2 Group 117 1.3 and Group 265 5.3 , p0.001. Conclusion: The use of alpha-adrenergic blockers for a minimum of three months or longer before prostate biopsy significantly reduces the incidence of FUI that may develop secondary to biopsy.

Article Details

Is there any effect of long term alpha-adrenergic blocker and a single dose antibiotic usage in reducing febrile urinary tract infections after prostate biopsy?

Authors:

Kubilay Sarıkaya | Muhammed Arif İbiş

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.1-6

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001282271

pISSN:

2636-8579

Urinary tract infection

prostate

core needle biopsy

Urinary tract infection

prostate

core needle biopsy

Issues

Article Details

Is there any effect of long term alpha-adrenergic blocker and a single dose antibiotic usage in reducing febrile urinary tract infections after prostate biopsy?

Authors: Kubilay Sarıkaya | Muhammed Arif İbiş

Publisher: MediHealth Academy Yayıncılık

Main Topics: Sağlık Kurumları Yönetimi

Journal: Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.1-6

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001282271

pISSN: 2636-8579

Urinary tract infection

prostate

core needle biopsy

Urinary tract infection

prostate

core needle biopsy

Issues

Authors:

Kubilay Sarıkaya | Muhammed Arif İbiş

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Sağlık Kurumları Yönetimi

Journal:

Journal of Health Sciences and Medicine Vol.6 Issue 1, pp.1-6

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001282271

pISSN:

2636-8579