Biologic Therapies in Autoimmune Diseases: A Review of Clinical Efficacy and Safety Trends

Muthanna A.S. Aljuboory; Zaman Atiea Sabah; Muntaha A. Abdulkareem

doi:10.29196/jubpas.v33i4.6142

Article Details

Biologic Therapies in Autoimmune Diseases: A Review of Clinical Efficacy and Safety Trends

Authors:

Muthanna A.S. Aljuboory | Zaman Atiea Sabah | Muntaha A. Abdulkareem

Publisher:

University of Babylon

Journal:

JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences Vol.33 Issue 4, pp.62-92

Document Type:

Article

Publication Date:

1/2025

Document Language:

English

Document ID (Org No.):

2001383327

pISSN:

2312-8135

DOI:

10.29196/jubpas.v33i4.6142

Keywords:

Abstract:

 Biologic therapies for rheumatologic illnesses, aimed at targeting molecules implicated in immune system mechanisms, offer an alternative to conventional treatments such as disease-altering anti-rheumatic medicines with additional immunosuppressive medications. Nonetheless, the existing limitations of biologic treatments, including the challenges of intravenous administration, the substantial prices of these pharmaceuticals, and the associated side events hinder their widespread use as first-line treatments. This review is an update on the recent research regarding the novel biologic medicines accessible. The review focuses on eight pharmaceuticals: Tocilizumab, Rituximab, Adalimumab, Ustekinumab, Infliximab Belimumab, Vedolizumab, and Secukinumab, utilized in the treatment of rheumatoid arthritis, spondyloarthritis, systemic lupus erythematosus, systemic sclerosis, or vasculitis.

Article Details

Biologic Therapies in Autoimmune Diseases: A Review of Clinical Efficacy and Safety Trends

Authors:

Muthanna A.S. Aljuboory | Zaman Atiea Sabah | Muntaha A. Abdulkareem

Publisher:

University of Babylon

Journal:

JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences Vol.33 Issue 4, pp.62-92

Document Type:

Article

Publication Date:

1/2025

Document Language:

English

Document ID (Org No.):

2001383327

pISSN:

2312-8135

DOI:

10.29196/jubpas.v33i4.6142

Biologic Therapies

rheumatoid arthritis

spondyloarthritis

systemic lupus erythematosus

systemic sclerosis.

Issues

Article Details

Biologic Therapies in Autoimmune Diseases: A Review of Clinical Efficacy and Safety Trends

Authors: Muthanna A.S. Aljuboory | Zaman Atiea Sabah | Muntaha A. Abdulkareem

Publisher: University of Babylon

Journal: JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences Vol.33 Issue 4, pp.62-92

Document Type: Article

Publication Date: 1/2025

Document Language: English

Document ID (Org No.): 2001383327

pISSN: 2312-8135

DOI: 10.29196/jubpas.v33i4.6142

Biologic Therapies

rheumatoid arthritis

spondyloarthritis

systemic lupus erythematosus

systemic sclerosis.

Issues

Authors:

Muthanna A.S. Aljuboory | Zaman Atiea Sabah | Muntaha A. Abdulkareem

Publisher:

University of Babylon

Journal:

JOURNAL OF UNIVERSITY OF BABYLON for Pure and Applied Sciences Vol.33 Issue 4, pp.62-92

Document Type:

Article

Publication Date:

1/2025

Document Language:

English

Document ID (Org No.):

2001383327

pISSN:

2312-8135

DOI:

10.29196/jubpas.v33i4.6142