Alterations in Lipid Peroxidation and Some Trace Elements Concentrations in Sera and Tissues Homogenates of Women with Benign and Malignant Cervix and Uterine Tumors

Hathama Razooki Hasan; Shatha Abd AL-Wadood Al-Shammaree

Article Details

Alterations in Lipid Peroxidation and Some Trace Elements Concentrations in Sera and Tissues Homogenates of Women with Benign and Malignant Cervix and Uterine Tumors

Authors:

Hathama Razooki Hasan | Shatha Abd AL-Wadood Al-Shammaree

Publisher:

Yarmouk University : The Deanship of Research and Graduate Studies

Main Topics:

Medicine

Journal:

Jordan Journal of Chemistry 2011 Vol.6 Issue 4, pp.453-465

Document Type:

Article

Publication Date:

12/2011

Document Language:

English

Document ID (Org No.):

27633

Frequency:

Quarterly

pISSN:

18149111

Descriptors:

Keywords:

Abstract:

 The levels of sera and tissues homogenates malondialdehyde MDA (one of the lipidperoxidation products), was measured by Hirayama et.al spectrophotometry method, and thesera concentrations of some trace elements: Copper (cu), Iron (Fe), and Zinc (Zn) wereevaluated in patients with benign cervix (n=28), malignant cervix (n=20), benign uterine tumors(n=33), and malignant uterine tumors (n=28),as measured by using flame atomic absorptionspectrophotometer. A significant increase (P<0.05) in MDA concentration were found in sera ofall above mentioned groups when compared with that of control group. However there were ahigh significant increase (P<0.005) in sera of pre-menopausal groups of patients with benign,malignant cervix and uterine tumors among the other groups. Tissues homogenates MDA levelsshowed significant increase (P<0.05) in case of cervix pre-malignancy (n=10), cervix (n=20) anduterus cancer (n=28) groups when compared with that of the other groups (n=68). The resultsindicated a significant decrease (P<0.05) in sera (Zn) concentration and a significant increase(P<0.05) in both sera (Cu) and (Fe) concentration in uterus and cervix cancer groups whencompared with that of the other groups.

Article Details

Alterations in Lipid Peroxidation and Some Trace Elements Concentrations in Sera and Tissues Homogenates of Women with Benign and Malignant Cervix and Uterine Tumors

Authors:

Hathama Razooki Hasan | Shatha Abd AL-Wadood Al-Shammaree

Publisher:

Yarmouk University : The Deanship of Research and Graduate Studies

Main Topics:

Medicine

Journal:

Jordan Journal of Chemistry 2011 Vol.6 Issue 4, pp.453-465

Document Type:

Article

Publication Date:

12/2011

Document Language:

English

Document ID (Org No.):

27633

Frequency:

Quarterly

pISSN:

18149111

Descriptors:

UTERINE DISEASES

NEOPLASMS

ZINC

TRACE ELEMENTS

COPPER

BLOOD SERUM

ANTIOXIDANTS

DISEASE RESISTANCE

Malondialdehyde

Zinc

Copper

Iron

Uterus tumors

Cervix tumor

Issues

Article Details

Authors: Hathama Razooki Hasan | Shatha Abd AL-Wadood Al-Shammaree

Publisher: Yarmouk University : The Deanship of Research and Graduate Studies

Main Topics: Medicine

Journal: Jordan Journal of Chemistry 2011 Vol.6 Issue 4, pp.453-465

Document Type: Article

Publication Date: 12/2011

Document Language: English

Document ID (Org No.): 27633

Frequency: Quarterly

pISSN: 18149111

Descriptors:

Issues

Authors:

Hathama Razooki Hasan | Shatha Abd AL-Wadood Al-Shammaree

Publisher:

Yarmouk University : The Deanship of Research and Graduate Studies

Main Topics:

Medicine

Journal:

Jordan Journal of Chemistry 2011 Vol.6 Issue 4, pp.453-465

Document Type:

Article

Publication Date:

12/2011

Document Language:

English

Document ID (Org No.):

27633

Frequency:

Quarterly

pISSN:

18149111