Assessment of the Role of Non-classical Human Leucocytic Antigens A-G (Hla-G) Variations on Hydatid Disease

Ateeq , Nayera S.; Hussein , Eman M.; Yahai , Nehal S.; Elzagawy , Sherine

Article Details

Assessment of the Role of Non-classical Human Leucocytic Antigens A-G (Hla-G) Variations on Hydatid Disease

Authors:

Ateeq , Nayera S. | Hussein , Eman M. | Yahai , Nehal S. | Elzagawy , Sherine

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2025 Vol.55 Issue 2, pp.217-224

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

273262

Frequency:

Tri-Annual

pISSN:

11100583

Descriptors:

Keywords:

Abstract:

 In Egypt, cystic echinococcosis (CE) is a public health problem that categorizes patients into susceptible or resistant groups referring to the immune system, particularly human leukocytic antigen (HLA) Class I & II. In the present study, relation between non-classical HLA -G alleles and the CE was achieved in a retrospective case-control study in Ismailia province. The study included 33 diseased and Control groups matching age, sex, and residence. To identify HLA-G alleles, Polymerase Chain Reaction (PCR) was performed. The frequency of non-classical HLA-G alleles indicated a significant difference between the two study groups in only two (0103 and 0105) out of seven. Allele 0103 was absent in 17 out of 33 (54.5%) patients, while it lacked in 2 control persons (6.1%), however the allele 0105 was lacking in 16 out of 33 (48.5%) patients, while it missed in 3 control persons (9.1%). Regarding cyst sizes, < 5 cm and ≥ 5 cm showed significant differences. There were no significant differences in HLA-G distri-bution concerning the affected organs.

Article Details

Assessment of the Role of Non-classical Human Leucocytic Antigens A-G (Hla-G) Variations on Hydatid Disease

Authors:

Ateeq , Nayera S. | Hussein , Eman M. | Yahai , Nehal S. | Elzagawy , Sherine

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2025 Vol.55 Issue 2, pp.217-224

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

273262

Frequency:

Tri-Annual

pISSN:

11100583

Descriptors:

CYSTIC DISEASES

HYDATIDOSIS

LEUKOCYTES

THERAPY

GENES

Hydatid Cyst

HLA-G

Genotyping

Cyst

Issues

Article Details

Authors: Ateeq , Nayera S. | Hussein , Eman M. | Yahai , Nehal S. | Elzagawy , Sherine

Publisher: The Egyptian Society of Parasitology

Main Topics: Medicine

Journal: Journal of the Egyptian Society of Parasitology 2025 Vol.55 Issue 2, pp.217-224

Document Type: Article

Publication Date: 8/2025

Document Language: English

Document ID (Org No.): 273262

Frequency: Tri-Annual

pISSN: 11100583

Descriptors:

Issues

Authors:

Ateeq , Nayera S. | Hussein , Eman M. | Yahai , Nehal S. | Elzagawy , Sherine

Publisher:

The Egyptian Society of Parasitology

Main Topics:

Medicine

Journal:

Journal of the Egyptian Society of Parasitology 2025 Vol.55 Issue 2, pp.217-224

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

273262

Frequency:

Tri-Annual

pISSN:

11100583