Clinical and Lab-Assessed Antibiotic Resistance Pattern of Uropathogens among Women with Acute Uncomplicated Cystitis

Abdelkhalik , Ahmed M.; Agha , Mohamed M.; Zaki , Ahmed M.; Tahoun , Ahmed

Article Details

Clinical and Lab-Assessed Antibiotic Resistance Pattern of Uropathogens among Women with Acute Uncomplicated Cystitis

Authors:

Abdelkhalik , Ahmed M. | Agha , Mohamed M. | Zaki , Ahmed M. | Tahoun , Ahmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.73 Issue 11, pp.7860-7868

Document Type:

Article

Publication Date:

10/2018

Document Language:

English

Document ID (Org No.):

135504

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

Keywords:

Abstract:

 Background: acute uncomplicated cystitis (AUC) in females is among the most frequent infections in community. Treatment of AUC in Egypt usually based on empirical therapy.Objectives: To determine the most common uropathogens and their pattern of resistance to commonly used antimicrobials aiming at finding a proper antibiotic which can be used as effective empirical therapy in AUC.Patients and Methods: Observational, hospital based, cross sectional study was performed. Three hundred and twelve female patients were recruited for the study with positive urine culture and clinical symptoms correlate with AUC during the period from December 2017 to August 2018.Results: Eight organisms were isolated. E. coli was the most common uropathogen and was isolated from 231 cases (74%). The next most common was Pseudomonas which was detected in 41 cases (13.1%). Other organisms include MRSA (6.1%), Klebsiella (2.2%), Enterococcus spp. (1.9%), proteus (1.3%), Acinetobacter and Staph. aureus (0.6%) each. Isolated uropathogens in this study were least resistant to Nitrofurantoin (47.1%). The highest resistance rate was to TMP/SMZ (87.8%). Resistance pattern to quinolones were 64.1%, 67% and 60.6% to Ciprofloxacin, Norfloxacinand and Levofloxacin respectively.Conclusion: The most common cause of community acquired AUC was E. coli. Nitrofurantoin can be used as a first line empirical therapy for AUC as it showed the least resistance pattern (47.1%). Antimicrobial resistance is a crucial issue which evolves continuously and thus more studies must be carried out in different regions and constanttime intervals.

Article Details

Clinical and Lab-Assessed Antibiotic Resistance Pattern of Uropathogens among Women with Acute Uncomplicated Cystitis

Authors:

Abdelkhalik , Ahmed M. | Agha , Mohamed M. | Zaki , Ahmed M. | Tahoun , Ahmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.73 Issue 11, pp.7860-7868

Document Type:

Article

Publication Date:

10/2018

Document Language:

English

Document ID (Org No.):

135504

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

CYSTITIS

URINARY TRACT DISEASES

ANTIBIOTICS

WOMEN

PATIENTS

EGYPT

Urinary Tract Infection

Acute Uncomplicated Cystitis

Antibiotic Resistance Pattern

Issues

Article Details

Authors: Abdelkhalik , Ahmed M. | Agha , Mohamed M. | Zaki , Ahmed M. | Tahoun , Ahmed

Publisher: Pan Arab League of Continuous Medical Education

Main Topics: Medicine

Journal: The Egyptian Journal of Hospital Medicine 2018 Vol.73 Issue 11, pp.7860-7868

Document Type: Article

Publication Date: 10/2018

Document Language: English

Document ID (Org No.): 135504

Frequency: Quarterly

eISSN: 20907125

pISSN: 16872002

Descriptors:

Issues

Authors:

Abdelkhalik , Ahmed M. | Agha , Mohamed M. | Zaki , Ahmed M. | Tahoun , Ahmed

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2018 Vol.73 Issue 11, pp.7860-7868

Document Type:

Article

Publication Date:

10/2018

Document Language:

English

Document ID (Org No.):

135504

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002