Non-obstructive acute CoronarySyndrome and Khat chewing

Mohammed Ben Mohammed Alsaadi; Khadeja Shafiq  Aman; Ahmed Saeed Almansoob

Article Details

Non-obstructive acute CoronarySyndrome and Khat chewing

Authors:

Mohammed Ben Mohammed Alsaadi | Khadeja Shafiq Aman | Ahmed Saeed Almansoob

Publisher:

University of Aden

Main Topics:

critical stenosis

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.423-436

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534910

pISSN:

2788-9327

Keywords:

Abstract:

 Nonobstructive coronary artery disease (NCAD)occurs in 10% to 25% of patients undergoing elective coronary angiography, while nonobstructive acute coronary syndrome (NACS) accounts up to 6% of patients with troponin-positive ACS. In Yemen, prior studies have assessed outcomes among myocardial infarction (MI)khat chewers, who had nonobstructive lesions on angiography. However; correlation between NACS and Khat use is yet not discussed. Our study aimed to defining the clinical outcomes of patients, presenting with unstable angina (UA) or non ST segment elevation myocardial infarction (NSTEMI), but had stenosis ≤ 50% on angiography. Our main goal is to show the association between outcomes and khat chewing among patients with NASC. Data for this retrospective study were obtained from the sector of health care and related clinics at the Yemeni Petroleum Company in Aden- from January 2005 through September 2010. The study group consisting of 114 to ACS patients was divided into two subgroups: patients with stenosis < 20% and patients with stenosis more than 20 but less than50%. They were compared with patients in a control group (n=213), who had critical coronary stenosis, sufficient enough to warrantenough (≥70%) percutaneous coronary intervention (PCI). Our results showed that patients with NACS were more likely to be female, younger, with fewer risk factors, compared to the control. MI or PCI occurred was in 1.75 % or 3.5% of patients with NACS and in 5.16% or 17.37% (respectively) of patients with critical obstructive ACS. Cardiac death was observed less frequently in patients with NACS, compared to those with critical obstructive disease (1.75 % vs 4.23%). Sub analysis of the study group showed that, the 2nd subgroup patients (stenosis 20%-50%) were older male with an increasing frequency of nondiabetic patients and heavy khat chewing, compared to the 1st subgroup (stenosis.

Article Details

Non-obstructive acute CoronarySyndrome and Khat chewing

Authors:

Mohammed Ben Mohammed Alsaadi | Khadeja Shafiq Aman | Ahmed Saeed Almansoob

Publisher:

University of Aden

Main Topics:

critical stenosis

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.423-436

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534910

pISSN:

2788-9327

Acute coronary syndrome

khat chewing

nonobstructive stenosis

critical stenosis

Issues

Article Details

Non-obstructive acute CoronarySyndrome and Khat chewing

Authors: Mohammed Ben Mohammed Alsaadi | Khadeja Shafiq Aman | Ahmed Saeed Almansoob

Publisher: University of Aden

Main Topics: critical stenosis

Journal: University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.423-436

Document Type: Article

Publication Date: 8/2016

Document Language: English

Document ID (Org No.): 2001534910

pISSN: 2788-9327

Acute coronary syndrome

khat chewing

nonobstructive stenosis

critical stenosis

Issues

Authors:

Mohammed Ben Mohammed Alsaadi | Khadeja Shafiq Aman | Ahmed Saeed Almansoob

Publisher:

University of Aden

Main Topics:

critical stenosis

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.423-436

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534910

pISSN:

2788-9327