Salivary IgA in Chronic Kidney Disease Patients Undergoing Hemodialysis in Missan Governorate

Faris Abid Hatem; Zaheda Jassim Mohammad

doi:10.12816/0015295

Article Details

Salivary IgA in Chronic Kidney Disease Patients Undergoing Hemodialysis in Missan Governorate

Authors:

Faris Abid Hatem | Zaheda Jassim Mohammad

Publisher:

College of Dentistry : University of Baghdad

Main Topics:

Medicine

Journal:

Journal of Baghdad College of Dentistry 2015 Vol.27 Issue 2, pp.54-57

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

71264

Frequency:

Quarterly

eISSN:

23115270

pISSN:

16800087

DOI:

10.12816/0015295

Descriptors:

Keywords:

Abstract:

 Background: Chronic kidney disease is a worldwide health problem, with adverse outcomes of cardiovasculardisease and premature death, can be divided into five stages, depending on how severe the damage is to thekidneys, or the level of decrease in kidney function, the final stage of chronic kidney disease is called end-stagerenal disease, salivary immunoglobulin A is the main immunoglobulin found in mucous secretions, including tears,saliva, colostrum and secretions from the genitourinary tract gastrointestinal tract, prostate and respiratoryepithelium. It is also found in small amounts in blood.This study aimedto measuresalivary flow rate andsalivaryimmunoglobulin Alevels in chronic kidney disease patients on hemodialysis treatment in comparison withhealthy control subjects.Materials and Methods: Ninety (90) subjects were participated in this study; 45 Patients undergoing hemodialysis withchronic kidney diseases; 45 health control subjects. Saliva collected was measured and levels of salivaryimmunoglobulin A were measured by Enzyme Link Immunosorbent Assay (Elisa).
Results:The present studyrevealed that the mean value of salivary flow rate in chronic kidney disease patients was(0.34 ± 0.19) ml/min, while for healthy control subjects was (1.02 ± 0.39) ml/min, there wasstatisticallysignificantlydecrease in salivary flow rate ofchronic kidney disease on hemodialysis patients as compared to control healthysubjects.The present study revealed that the (Mean±SD) of the immunoglobulin A in chronic kidney disease patientson hemodialysis (388.81±227.86) μg./ml, while in control group (273.98±155.89) μg./ml, the result revealed statisticallysignificant increase in chronic kidney disease patients on hemodialysis as compared to control subjects.
Conclusions: Salivary immunoglobulin (IgA) reflects the functional capacity of the glands. Increased concentrationof this component is usually marker of a poor general condition.

Article Details

Salivary IgA in Chronic Kidney Disease Patients Undergoing Hemodialysis in Missan Governorate

Authors:

Faris Abid Hatem | Zaheda Jassim Mohammad

Publisher:

College of Dentistry : University of Baghdad

Main Topics:

Medicine

Journal:

Journal of Baghdad College of Dentistry 2015 Vol.27 Issue 2, pp.54-57

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

71264

Frequency:

Quarterly

eISSN:

23115270

pISSN:

16800087

DOI:

10.12816/0015295

Descriptors:

MOUTH DISEASES

SALIVARY GLANDS

DISEASES OF SALIVARY GLANDS

KIDNEY DISEASES

MEDICAL RESEARCH

IRAQ

Chronic Kidney Disease

Hemodialysis

Salivary Flow Rate and Salivary Immunoglobulin A.

Issues

Article Details

Authors: Faris Abid Hatem | Zaheda Jassim Mohammad

Publisher: College of Dentistry : University of Baghdad

Main Topics: Medicine

Journal: Journal of Baghdad College of Dentistry 2015 Vol.27 Issue 2, pp.54-57

Document Type: Article

Publication Date: 6/2015

Document Language: English

Document ID (Org No.): 71264

Frequency: Quarterly

eISSN: 23115270

pISSN: 16800087

DOI: 10.12816/0015295

Descriptors:

Issues

Authors:

Faris Abid Hatem | Zaheda Jassim Mohammad

Publisher:

College of Dentistry : University of Baghdad

Main Topics:

Medicine

Journal:

Journal of Baghdad College of Dentistry 2015 Vol.27 Issue 2, pp.54-57

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

71264

Frequency:

Quarterly

eISSN:

23115270

pISSN:

16800087

DOI:

10.12816/0015295