Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

Enver ÜÇBİLEK; Bahri ABAYLI; Mahmut Bakir KOYUNCU; Durdane MIDIKLI; Süveyda GÖZÜKÜÇÜK; Alper AKDAĞ; Osman ÖZDOĞAN; Engin ALTINTAŞ; Orhan SEZGİN

Article Details

Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

Authors:

Enver ÜÇBİLEK | Bahri ABAYLI | Mahmut Bakir KOYUNCU | Durdane MIDIKLI | Süveyda GÖZÜKÜÇÜK | Alper AKDAĞ | Osman ÖZDOĞAN | Engin ALTINTAŞ | Orhan SEZGİN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.66-71

Document Type:

Article

Publication Date:

1/2016

Document Language:

Turkish

Document ID (Org No.):

2000752301

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: The most common hepatitis C virus (HCV) genotype in Turkey is genotype 1. However, there has not been a study about the distribution of HCV genotypes among intravenous drug users (IVDUs) in the Çukurova region of Turkey. This study was planned to understand if there is a difference between IVDUs and the normal population.  Materials and methods: Between May 2010 and May 2014, anti-HCV positive IVDUs who applied to the 6 hospitals in the Çukurova region of Turkey were included in this study. Their HCV genotypes were studied.   Results: Ninety-seven anti-HCV positive IVDUs were screened in terms of HCV RNA and genotype. Ten were excluded from the study because their HCV RNA results were negative. Fifty-one of the 87 patients (58.6%) had genotype 3. Genotype 2 was detected in 26 (29.9%) and genotype 1 was detected in 10 (11.5%) patients.   Conclusion: HCV genotypes seem to be different between the normal population and IVDUs according to studies worldwide. Among IVDUs, we detected a dominance of genotype 3 and genotype 2, which is apparently different from the normal population. The reason for this difference can be simply explained by infection through shared needles. However, there may still be a different immunological response in IVDUs, the investigation of which may lead to further studies.

Article Details

Distribution of hepatitis C virus genotypes among intravenous drug users in the Çukurova region of Turkey

Authors: Enver ÜÇBİLEK | Bahri ABAYLI | Mahmut Bakir KOYUNCU | Durdane MIDIKLI | Süveyda GÖZÜKÜÇÜK | Alper AKDAĞ | Osman ÖZDOĞAN | Engin ALTINTAŞ | Orhan SEZGİN

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.66-71

Document Type: Article

Publication Date: 1/2016

Document Language: Turkish

Document ID (Org No.): 2000752301

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Enver ÜÇBİLEK | Bahri ABAYLI | Mahmut Bakir KOYUNCU | Durdane MIDIKLI | Süveyda GÖZÜKÜÇÜK | Alper AKDAĞ | Osman ÖZDOĞAN | Engin ALTINTAŞ | Orhan SEZGİN

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2016 Vol.46 Issue 1, pp.66-71

Document Type:

Article

Publication Date:

1/2016

Document Language:

Turkish

Document ID (Org No.):

2000752301

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144