The Importance of Anticardiolipin Antibody and Antiplatelet Antibody in the Development of Thrombocytopenia in Cirrhosis

Hasan YAVUZ

Article Details

The Importance of Anticardiolipin Antibody and Antiplatelet Antibody in the Development of Thrombocytopenia in Cirrhosis

Authors:

Hasan YAVUZ

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2000 Vol.30 Issue 6, pp.589-594

Document Type:

Article

Publication Date:

5/2000

Document Language:

Turkish

Document ID (Org No.):

2000757494

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Keywords:

Abstract:

 

Objective: The purpose of the  present study was to investigate the effects of  the presence of hypersplenism, antiplatelet  antibody and anticardiolipin antibody, which  are thought to be important factors, on the  development of thrombocytopenia in patients  with cirrhosis with viral etiology.  Methods: This study includes 44 patients  with cirrhosis related to HBV and HCV, and  12 healthy control subjects. Spleen size was  evaluated by ultrasonography, the presence of  antiplatelet antibody by flow cytometry, and  IgG and IgM isotypes of anticardiolipin anti-  body by enzyme immunoassay.  Results: There was a significant difference in  ultrasonographic spleen size between the  patients with and without thrombocytopenia  (p.

 

Objective: The purpose of the  present study was to investigate the effects of  the presence of hypersplenism, antiplatelet  antibody and anticardiolipin antibody, which  are thought to be important factors, on the  development of thrombocytopenia in patients  with cirrhosis with viral etiology.  Methods: This study includes 44 patients  with cirrhosis related to HBV and HCV, and  12 healthy control subjects. Spleen size was  evaluated by ultrasonography, the presence of  antiplatelet antibody by flow cytometry, and  IgG and IgM isotypes of anticardiolipin anti-  body by enzyme immunoassay.  Results: There was a significant difference in  ultrasonographic spleen size between the  patients with and without thrombocytopenia  (p.

Article Details

The Importance of Anticardiolipin Antibody and Antiplatelet Antibody in the Development of Thrombocytopenia in Cirrhosis

Authors: Hasan YAVUZ

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2000 Vol.30 Issue 6, pp.589-594

Document Type: Article

Publication Date: 5/2000

Document Language: Turkish

Document ID (Org No.): 2000757494

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Cirrhosis

thrombocytopenia

anticardiolipin antibody

antiplatelet antibody

Issues

Authors:

Hasan YAVUZ

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2000 Vol.30 Issue 6, pp.589-594

Document Type:

Article

Publication Date:

5/2000

Document Language:

Turkish

Document ID (Org No.):

2000757494

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144