Antidiabetic Effect of Cinclidotus pachylomoides Bizot (Bryophyta) Extract

Ulaş Değirmenci; Tülay Ezer

Article Details

Antidiabetic Effect of Cinclidotus pachylomoides Bizot (Bryophyta) Extract

Authors:

Ulaş Değirmenci | Tülay Ezer

Publisher:

Cankiri Karatekin University

Main Topics:

Bitki Bilimi (Diğer)

Journal:

Anatolian Bryology Vol.10 Issue 2, pp.89-94

Document Type:

Article

Publication Date:

5/2024

Document Language:

Turkish

Document ID (Org No.):

2001332887

pISSN:

2149-5920

Keywords:

Abstract:

 Type 2 diabetes T2D is recognized as one of the most important public health problems in all nations in the 21st century. Chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of various organs. Postprandial hyperglycemia is mainly caused by rapid absorption of glucose in the intestine, where α-glucosidase plays an important role in the hydrolysis of dietary carbohydrates. Inhibition of α-glucosidase is considered as an effective approach in the treatment of type 2 diabetes. Bryophytes are the second largest taxonomic group in the plant kingdom and are an integral part of biodiversity. Recently, a large number of different bioactive substances have been isolated from liverworts and mosses. In this study, the α-glucosidase enzyme inhibition effect of the extract of the moss species Cinclidotus pachylomoides Bizot Bryophyta, which was characterized for the first time by GKKS method, was investigated and it was found to have a moderate α-glucosidase enzyme inhibition effect.

 Type 2 diabetes T2D is recognized as one of the most important public health problems in all nations in the 21st century. Chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of various organs. Postprandial hyperglycemia is mainly caused by rapid absorption of glucose in the intestine, where α-glucosidase plays an important role in the hydrolysis of dietary carbohydrates. Inhibition of α-glucosidase is considered as an effective approach in the treatment of type 2 diabetes. Bryophytes are the second largest taxonomic group in the plant kingdom and are an integral part of biodiversity. Recently, a large number of different bioactive substances have been isolated from liverworts and mosses. In this study, the α-glucosidase enzyme inhibition effect of the extract of the moss species Cinclidotus pachylomoides Bizot Bryophyta, which was characterized for the first time by GKKS method, was investigated and it was found to have a moderate α-glucosidase enzyme inhibition effect.

 Type 2 diabetes T2D is recognized as one of the most important public health problems in all nations in the 21st century. Chronic hyperglycemia of diabetes is associated with long-term damage, dysfunction and failure of various organs. Postprandial hyperglycemia is mainly caused by rapid absorption of glucose in the intestine, where α-glucosidase plays an important role in the hydrolysis of dietary carbohydrates. Inhibition of α-glucosidase is considered as an effective approach in the treatment of type 2 diabetes. Bryophytes are the second largest taxonomic group in the plant kingdom and are an integral part of biodiversity. Recently, a large number of different bioactive substances have been isolated from liverworts and mosses. In this study, the α-glucosidase enzyme inhibition effect of the extract of the moss species Cinclidotus pachylomoides Bizot Bryophyta, which was characterized for the first time by GKKS method, was investigated and it was found to have a moderate α-glucosidase enzyme inhibition effect.

 Tip 2 diyabet T2D, 21. yüzyılda tüm uluslarda en önemli halk sağlığı sorunlarından biri olarak kabul edilmektedir. Diyabetin kronik hiperglisemisi, çeşitli organların uzun vadeli hasarı, işlev bozukluğu ve yetmezliği ile ilişkilidir. Postprandiyal hiperglisemi esas olarak bağırsakta glikozun hızlı emiliminden kaynaklanır ve burada α-glukozidaz diyetle alınan karbonhidratların hidrolizinde önemli bir rol oynar. Tip 2 diyabetin tedavisinde α-glukozidaz inhibisyonu etkili bir yaklaşım olarak kabul edilmektedir. Briyofitler, bitkiler aleminin ikinci büyük taksonomik grubu olup biyoçeşitliliğin ayrılmaz bir parçasıdır. Son zamanlarda ciğerotlarından ve karayosunlarından çok sayıda farklı biyoaktif madde izole edilmiştir. Bu çalışmada da GKKS yöntemiyle ilk kez karakterizasyonu yapılan karayosunu türü Cinclidotus pachylomoides Bizot Bryophyta ekstraktının α-glukozidaz enzim inhibisyon etkisi araştırılmış olup orta düzeyde α-glukozidaz enzim inhibisyon etkisi olduğu tespit edilmiştir.

Article Details

Antidiabetic Effect of Cinclidotus pachylomoides Bizot (Bryophyta) Extract

Authors:

Ulaş Değirmenci | Tülay Ezer

Publisher:

Cankiri Karatekin University

Main Topics:

Bitki Bilimi (Diğer)

Journal:

Anatolian Bryology Vol.10 Issue 2, pp.89-94

Document Type:

Article

Publication Date:

5/2024

Document Language:

Turkish

Document ID (Org No.):

2001332887

pISSN:

2149-5920

Bryophyte

Cinclidotus pachylomoides

mosses

type 2 diabetes

α-glucosidaseBriyofit

Cinclidotus pachylomoides

karayosunu

tip 2 diyabet

α-glukozidaz

Issues

Article Details

Authors: Ulaş Değirmenci | Tülay Ezer

Publisher: Cankiri Karatekin University

Main Topics: Bitki Bilimi (Diğer)

Journal: Anatolian Bryology Vol.10 Issue 2, pp.89-94

Document Type: Article

Publication Date: 5/2024

Document Language: Turkish

Document ID (Org No.): 2001332887

pISSN: 2149-5920

Issues

Authors:

Ulaş Değirmenci | Tülay Ezer

Publisher:

Cankiri Karatekin University

Main Topics:

Bitki Bilimi (Diğer)

Journal:

Anatolian Bryology Vol.10 Issue 2, pp.89-94

Document Type:

Article

Publication Date:

5/2024

Document Language:

Turkish

Document ID (Org No.):

2001332887

pISSN:

2149-5920