Histopathological patterns of inflammation in benign and malignant prostatic diseases. Inflammation as risk factors for prostate cancer among Yemeni patients

Muna Anwer Kutb; Hussun Saeed Jezan

Article Details

Histopathological patterns of inflammation in benign and malignant prostatic diseases. Inflammation as risk factors for prostate cancer among Yemeni patients

Authors:

Muna Anwer Kutb | Hussun Saeed Jezan

Publisher:

University of Aden

Main Topics:

Yemen

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.409-421

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534909

pISSN:

2788-9327

Keywords:

Abstract:

 Prostatic diseases are responsible for significant morbidity and mortality among adult males worldwide. Most frequently encountered diseases affecting prostate are prostatitis, benign prostatic hyperplasia (BPH) and prostatic cancer.
Paraffin blocks of prostatic tissues of 694 biopsies were selected retrospectively, from the private laboratories in Aden governorate – Yemen from January 2010 – March 2015. Hematoxylin and eosin slides for the corresponding paraffin-embedded formalin-fixed blocks were examined to identify and confirm the presence and type of inflammation in benign prostatic lesions, prostatic intraepithelial neoplasia and carcinoma. Data were entered to the SPSS program (version 22), obtaining frequencies, percentages and chi-square tests. The risk of malignancy associated with inflammation was estimated compared to those having non-inflammatory prostatic lesions. The tests were conducted with the 95% confidence interval and p-values of ≤ 0.05 were considered statistically significant. 
Inflammation was found commonly in benign prostatic hyperplasia{78.2%}, in prostatic intraepithelial neoplasia {7.7%} and prostate cancer (92.3%}, most of which was chronic(ptwo folds).

Article Details

Histopathological patterns of inflammation in benign and malignant prostatic diseases. Inflammation as risk factors for prostate cancer among Yemeni patients

Authors:

Muna Anwer Kutb | Hussun Saeed Jezan

Publisher:

University of Aden

Main Topics:

Yemen

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.409-421

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534909

pISSN:

2788-9327

Chronic inflammation

benign prostatic lesions

prostate cancer

Yemen

Issues

Article Details

Histopathological patterns of inflammation in benign and malignant prostatic diseases. Inflammation as risk factors for prostate cancer among Yemeni patients

Authors: Muna Anwer Kutb | Hussun Saeed Jezan

Publisher: University of Aden

Main Topics: Yemen

Journal: University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.409-421

Document Type: Article

Publication Date: 8/2016

Document Language: English

Document ID (Org No.): 2001534909

pISSN: 2788-9327

Chronic inflammation

benign prostatic lesions

prostate cancer

Yemen

Issues

Authors:

Muna Anwer Kutb | Hussun Saeed Jezan

Publisher:

University of Aden

Main Topics:

Yemen

Journal:

University of Aden Journal of Natural and Applied Sciences Vol.20 Issue 2, pp.409-421

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

2001534909

pISSN:

2788-9327