EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS

Ezgican ULAÇ; Pelin KÖSEOĞLU YILMAZ; Ufuk KOLAK

doi:https://doi.org/10.3153/FH19005

Article Details

EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS

Authors:

Ezgican ULAÇ | Pelin KÖSEOĞLU YILMAZ | Ufuk KOLAK

Main Topics:

Life sciences

Journal:

Food and Health 2019 Vol.5 Issue 1, pp.39-47

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000419996

DOI:

https://doi.org/10.3153/FH19005

Abstract:

 


The
aim of this study was to determine total phenolic and total flavonoid contents,
antioxidant and anticholinesterase activities of the hexane, acetone and
ethanol extracts prepared from mantle, rosemary, thistle, mallow and nettle
commonly consumed for medicinal and nutraceutical purposes in Turkey and all
around the world. DPPH free radical, ABTS cation radical and superoxide anion
radical scavenging assays, and Ellman method were used to establish the antioxidant
and anticholinesterase potential of the extracts, respectively. Total phenolic
and total flavonoid contents of the mantle ethanol extract were found to be the
richest extract among the others. Mantle ethanol and thistle hexane extracts in
DPPH free radical scavenging method (88.03% and 88.07%, respectively), and acetone and ethanol extracts of mantle and
rosemary in ABTS cation radical scavenging assay showed the highest
inhibition (88.60% and 89.73%, respectively)
at 100 μg/mL concentration. None of the
extracts exhibited superoxide anion radical scavenging activity. Nettle ethanol
extract indicated higher butyrylcholinesterase inhibitory activity (92.68%)
than galanthamine, mallow acetone extract as galanthamine, mantle hexane,
mallow hexane and ethanol, and nettle acetone extracts almost as galanthamine.
To our knowledge, ABTS cation radical and superoxide anion radical scavenging
activities, and anticholinesterase potential of the extracts prepared from
mantle leaves and flowers, anticholinesterase effect of thistle seeds extracts,
ABTS cation radical scavenging activity and butyrylcholinesterase inhibitory
activity of the extracts prepared from mallow leaves and flowers were investigated
for the first time in this study.



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Article Details

EVALUATION OF ANTIOXIDANT AND CHOLINESTERASE INHIBITORY ACTIVITIES OF SOME MEDICINAL PLANTS

Authors: Ezgican ULAÇ | Pelin KÖSEOĞLU YILMAZ | Ufuk KOLAK

Main Topics: Life sciences

Journal: Food and Health 2019 Vol.5 Issue 1, pp.39-47

Document Type: Article

Publication Date: 12/2018

Document Language: English

Document ID (Org No.): 2000419996

DOI: https://doi.org/10.3153/FH19005

Issues

Authors:

Ezgican ULAÇ | Pelin KÖSEOĞLU YILMAZ | Ufuk KOLAK

Main Topics:

Life sciences

Journal:

Food and Health 2019 Vol.5 Issue 1, pp.39-47

Document Type:

Article

Publication Date:

12/2018

Document Language:

English

Document ID (Org No.):

2000419996

DOI:

https://doi.org/10.3153/FH19005