Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

Tuba MERT; Tuğçe FAFAL; Bijen KIVÇAK; H. Tansel ÖZTÜRK

Article Details

Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

Authors:

Tuba MERT | Tuğçe FAFAL | Bijen KIVÇAK | H. Tansel ÖZTÜRK

Publisher:

Hacettepe University

Journal:

Hacettepe University Journal of the Faculty of Pharmacy 2010 Issue 1, pp.17-24

Document Type:

Article

Publication Date:

12/2009

Document Language:

English

Document ID (Org No.):

2000454409

Frequency:

Quarterly

eISSN:

2458-8806

Abstract:

 

The antimicrobial and cytotoxic activities of n-hexane, methanol,  ethanol, ethyl acetate and water extracts of Alcea rosea L. flowers were  investigated. The antimicrobial activities of the extracts were reported  against Escherichia coli ATCC 29998, Escherichia coli ATCC 25922, Escherichia  coli ATCC 11230, Staphylococcus aureus ATCC 6538, Staphylococcus  aureus ATCC 29213, Staphylococcus epidermidis ATCC 12228, Salmonella  thyphimurium CCM 5445, Enterobacter cloacae ATCC 13047, Enterococcus  faecalis ATCC 29212, Pseudomonas aeroginosa ATCC 27853  as bacteria and Candida albicans ATCC 10239 as yeastlike fungi by disc  diffusion method.  These extracts were also tested for cytotoxic activity by brine shrimp  assay. Ethyl acetate extract showed cytotoxic activity against brine  shrimp.

 

Bu çalışmada, Alcea rosea L.’nin çiceklerinin n-hegzan, metanol, etanol,  etil asetat ve su ekstrelerinin, antimikrobiyal ve sitotoksik aktiviteleri  değerlendirildi. Ekstrelerin antimikrobiyal aktiviteleri, bakteri olarak  Escherichia coli ATCC 29998, Escherichia coli ATCC 25922, ATCC 29213,  Staphylococcus epidermidis ATCC 12228, Salmonella thyphimurium CCM  5445, Enterobacter cloacae ATCC 13047, Enterococcus faecalis ATCC  29212, Pseudomonas aeroginosa ATCC 27853 ve mantar olarak Candida  albicans ATCC 10239 ’ a karşı disk difüzyon metodu ile tayin edildi.  Ekstrelerin sitotoksik aktiviteleri Brine shrimp yöntemiyle  değerlendirildi. Etil asetat ekstresi Brine shrimp’e karşı sitotoksik aktivite  gösterdi.

Article Details

Antimicrobial and Cytotoxic Activities of the Extracts Obtained from the Flowers of Alcea Rosea L.

Authors: Tuba MERT | Tuğçe FAFAL | Bijen KIVÇAK | H. Tansel ÖZTÜRK

Publisher: Hacettepe University

Journal: Hacettepe University Journal of the Faculty of Pharmacy 2010 Issue 1, pp.17-24

Document Type: Article

Publication Date: 12/2009

Document Language: English

Document ID (Org No.): 2000454409

Frequency: Quarterly

eISSN: 2458-8806

Issues

Authors:

Tuba MERT | Tuğçe FAFAL | Bijen KIVÇAK | H. Tansel ÖZTÜRK

Publisher:

Hacettepe University

Journal:

Hacettepe University Journal of the Faculty of Pharmacy 2010 Issue 1, pp.17-24

Document Type:

Article

Publication Date:

12/2009

Document Language:

English

Document ID (Org No.):

2000454409

Frequency:

Quarterly

eISSN:

2458-8806