Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment

Yaşar Kemal Duymaz

Article Details

Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment

Authors:

Yaşar Kemal Duymaz

Publisher:

Istanbul University

Main Topics:

Otorhinolaryngology

Journal:

The Turkish Journal of Ear Nose and Throat Vol.34 Issue 1, pp.8-12

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001319172

pISSN:

2602-4837

Keywords:

Abstract:

 Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature. Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018. Nonlaryngeal head and neck malignancies and inaccessible patient records were excluded. The study evaluated factors including tumor location, tumor stage, lymph node metastasis, surgical approach, complications, histopathological findings, and adjuvant therapy. Statistical analysis involved descriptive methods, frequencies, and ratios, with outcomes compared to existing literature. Results: The cohort primarily consisted of male patients 91.7 with an average age of 58.04 years. Squamous cell carcinoma was the predominant histopathological type 98.8, exhibiting various degrees of differentiation. Most patients presented with advanced-stage disease III or IV, with 53.6 undergoing total laryngectomy. Neck dissection was performed in 95.2 of cases, and 69 received postoperative radiotherapy. The 5-year overall survival rate was 72.2, with a recurrence rate of 7.1. Conclusion: This study reveals that supraglottic laryngeal cancer, predominantly affecting older males, is frequently diagnosed at advanced stages. Surgical intervention resulted in a 5-year survival rate consistent with existing literature. Despite the limitation of its retrospective design and the small, single-center sample, the findings support current treatment modalities while underscoring the importance of early detection and further research.

 Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature. Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018. Nonlaryngeal head and neck malignancies and inaccessible patient records were excluded. The study evaluated factors including tumor location, tumor stage, lymph node metastasis, surgical approach, complications, histopathological findings, and adjuvant therapy. Statistical analysis involved descriptive methods, frequencies, and ratios, with outcomes compared to existing literature. Results: The cohort primarily consisted of male patients 91.7 with an average age of 58.04 years. Squamous cell carcinoma was the predominant histopathological type 98.8, exhibiting various degrees of differentiation. Most patients presented with advanced-stage disease III or IV, with 53.6 undergoing total laryngectomy. Neck dissection was performed in 95.2 of cases, and 69 received postoperative radiotherapy. The 5-year overall survival rate was 72.2, with a recurrence rate of 7.1. Conclusion: This study reveals that supraglottic laryngeal cancer, predominantly affecting older males, is frequently diagnosed at advanced stages. Surgical intervention resulted in a 5-year survival rate consistent with existing literature. Despite the limitation of its retrospective design and the small, single-center sample, the findings support current treatment modalities while underscoring the importance of early detection and further research.

 Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature. Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018. Nonlaryngeal head and neck malignancies and inaccessible patient records were excluded. The study evaluated factors including tumor location, tumor stage, lymph node metastasis, surgical approach, complications, histopathological findings, and adjuvant therapy. Statistical analysis involved descriptive methods, frequencies, and ratios, with outcomes compared to existing literature. Results: The cohort primarily consisted of male patients 91.7 with an average age of 58.04 years. Squamous cell carcinoma was the predominant histopathological type 98.8, exhibiting various degrees of differentiation. Most patients presented with advanced-stage disease III or IV, with 53.6 undergoing total laryngectomy. Neck dissection was performed in 95.2 of cases, and 69 received postoperative radiotherapy. The 5-year overall survival rate was 72.2, with a recurrence rate of 7.1. Conclusion: This study reveals that supraglottic laryngeal cancer, predominantly affecting older males, is frequently diagnosed at advanced stages. Surgical intervention resulted in a 5-year survival rate consistent with existing literature. Despite the limitation of its retrospective design and the small, single-center sample, the findings support current treatment modalities while underscoring the importance of early detection and further research.

 Objective: This study sought to retrospectively examine the clinical outcomes of patients treated for supraglottic laryngeal cancer at a single center over a decade, assess the efficacy of surgical interventions, and evaluate survival rates in comparison to current literature. Materials and Methods: A retrospective analysis was conducted on 84 patients diagnosed with supraglottic laryngeal cancer who underwent surgical treatment between January 2008 and December 2018. Nonlaryngeal head and neck malignancies and inaccessible patient records were excluded. The study evaluated factors including tumor location, tumor stage, lymph node metastasis, surgical approach, complications, histopathological findings, and adjuvant therapy. Statistical analysis involved descriptive methods, frequencies, and ratios, with outcomes compared to existing literature. Results: The cohort primarily consisted of male patients 91.7 with an average age of 58.04 years. Squamous cell carcinoma was the predominant histopathological type 98.8, exhibiting various degrees of differentiation. Most patients presented with advanced-stage disease III or IV, with 53.6 undergoing total laryngectomy. Neck dissection was performed in 95.2 of cases, and 69 received postoperative radiotherapy. The 5-year overall survival rate was 72.2, with a recurrence rate of 7.1. Conclusion: This study reveals that supraglottic laryngeal cancer, predominantly affecting older males, is frequently diagnosed at advanced stages. Surgical intervention resulted in a 5-year survival rate consistent with existing literature. Despite the limitation of its retrospective design and the small, single-center sample, the findings support current treatment modalities while underscoring the importance of early detection and further research.

Article Details

Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment

Authors:

Yaşar Kemal Duymaz

Publisher:

Istanbul University

Main Topics:

Otorhinolaryngology

Journal:

The Turkish Journal of Ear Nose and Throat Vol.34 Issue 1, pp.8-12

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001319172

pISSN:

2602-4837

Supraglottic laryngeal cancer

squamous cell carcinoma

neck dissection

total laryngectomy

partial laryngectomy

Issues

Article Details

Clinical Outcomes of Supraglottic Laryngeal Cancer: Insights from a Decade of Surgical Treatment

Authors: Yaşar Kemal Duymaz

Publisher: Istanbul University

Main Topics: Otorhinolaryngology

Journal: The Turkish Journal of Ear Nose and Throat Vol.34 Issue 1, pp.8-12

Document Type: Article

Publication Date: 3/2024

Document Language: English

Document ID (Org No.): 2001319172

pISSN: 2602-4837

Supraglottic laryngeal cancer

squamous cell carcinoma

neck dissection

total laryngectomy

partial laryngectomy

Issues

Authors:

Yaşar Kemal Duymaz

Publisher:

Istanbul University

Main Topics:

Otorhinolaryngology

Journal:

The Turkish Journal of Ear Nose and Throat Vol.34 Issue 1, pp.8-12

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001319172

pISSN:

2602-4837