Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators

Esra Akyüz Özkan; Demet Gür Vural

Article Details

Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators

Authors:

Esra Akyüz Özkan | Demet Gür Vural

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.340-345

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001300274

pISSN:

2619-9203

Keywords:

Abstract:

 Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate TA samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator HMV. Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 bioMeriux, France automated identification system. The patients age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia VAP patients, 72 79 were male and mean age was 91.64  64.07 months. The most common reason for referral was fever and dyspnea and 43.76 of the patients were diagnosed with cerebral palsyepilepsy and 10.4 with syndromes. Of the samples; 12 13.3 were defined as Gram-positive and 79 86.7 as Gram-negative. Pseudomonas aeruginosa was detected in 44 48.4 samples, Serratia marcescens in 9 9.9, Klebsiella spp. in 8 8.8 and Staphylococcus aureus was in 12 13.3 samples. Carbapenem resistance was 18.75 for Pseudomonas aeruginosa, 16 for Klebsiella spp, 12.5 for Escherichia coli and 12 for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.

 Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate TA samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator HMV. Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 bioMeriux, France automated identification system. The patients age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia VAP patients, 72 79 were male and mean age was 91.64  64.07 months. The most common reason for referral was fever and dyspnea and 43.76 of the patients were diagnosed with cerebral palsyepilepsy and 10.4 with syndromes. Of the samples; 12 13.3 were defined as Gram-positive and 79 86.7 as Gram-negative. Pseudomonas aeruginosa was detected in 44 48.4 samples, Serratia marcescens in 9 9.9, Klebsiella spp. in 8 8.8 and Staphylococcus aureus was in 12 13.3 samples. Carbapenem resistance was 18.75 for Pseudomonas aeruginosa, 16 for Klebsiella spp, 12.5 for Escherichia coli and 12 for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.

 Purpose: To investigate the underlying diseases, and complaints of patients upon admission, isolated microorganisms from tracheal aspirate TA samples and their resistance to antibiotics in patients followed up with a home mechanic ventilator HMV. Materials and Methods: Between January 1, 2020 and January 1, 2021, TA cultures, identification of bacteria and their antibiotic susceptibilities were evaluated by VITEK 2 bioMeriux, France automated identification system. The patients age, gender, underlying diseases, duration of home ventilator use, complaints, and laboratory data were reviewed. Results: Of the 91 prediagnosed ventilator-associated pneumonia VAP patients, 72 79 were male and mean age was 91.64  64.07 months. The most common reason for referral was fever and dyspnea and 43.76 of the patients were diagnosed with cerebral palsyepilepsy and 10.4 with syndromes. Of the samples; 12 13.3 were defined as Gram-positive and 79 86.7 as Gram-negative. Pseudomonas aeruginosa was detected in 44 48.4 samples, Serratia marcescens in 9 9.9, Klebsiella spp. in 8 8.8 and Staphylococcus aureus was in 12 13.3 samples. Carbapenem resistance was 18.75 for Pseudomonas aeruginosa, 16 for Klebsiella spp, 12.5 for Escherichia coli and 12 for Acinetobacter baumannii. Conclusion: TA culture should be taken from patients with HMV who were admitted with signs of infection such as fever and respiratory distress and treatment should be arranged according to the result. It was observed that the TA culture antibiotic resistance rates of the patients with HMV were lower than the TA cultures sent from the patients hospitalized in the intensive care unit in the literature.

 Amaç: Evde mekanik ventilator EMV ile takip edilen hastaların altta yatan hastalıkları, başvuru şikayetleri, trakeal aspirat TA kültürlerinden alınan örneklerden izole edilen mikroorganizmalar ve antibiyotiklere dirençlerinin araştırılması amaçlandı. Araçlar ve Yöntem: 1 Ocak 2020  1 Ocak 2021 tarihleri arasında TA kültürleri, bakterilerin tanımlanması ve antibiyotik duyarlılıkları VITEK 2 bioMeriux, Fransa otomatik tanımlama sistemi ile değerlendirildi. Hasta dosyalarından hastaların yaşı, cinsiyeti, altta yatan hastalıkları, evde ventilatör kullanım süreleri, şikayetleri ve laboratuvar verileri incelendi. Bulgular: Çalışmada incelenen 91 ventilatör ilişkili pnömoni VİP hastalarının 72si 79 erkek ve ortalama yaş 91.64  64.07 ay idi. En sık başvuru nedeni ateş ve nefes darlığı olup, hastaların 43.76sı serebral palsiepilepsi ve 10.4ü sendrom tanısı aldı. Örneklerden; 12si 13.3 Gram pozitif, 79u 86.7 Gram negatif olarak tanımlandı. 44 48.4 örnekte Pseudomonas aeruginosa, 9 9.9 örnekte Serratia marcescens, 8 8.8 örnekte Klebsiella spp, 12 13.3 örnekte Staphylococcus aureus tespit edildi. Karbapenem direnci Pseudomonas aeruginosa için 18.75, Klebsiella spp için 16, Escherichia coli için 12.5 ve Acinetobacter baumannii için 12 idi. Sonuç: Ateş ve solunum sıkıntısı gibi enfeksiyon bulguları ile başvuran EMV hastalardan TA kültürü alınmalı ve sonuca göre tedavi düzenlenmelidir. Evde EMV ile takip edilen hastaların TA kültürü antibiyotik direnç oranlarının literatürdeki yoğun bakımda yatan hastalardan gönderilen TA kültürlerine göre daha düşük olduğu gözlendi.

Article Details

Evaluation of Tracheal Aspirate Cultures of Patients Followed with Home Mechanical Ventilators

Authors:

Esra Akyüz Özkan | Demet Gür Vural

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.340-345

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001300274

pISSN:

2619-9203

Antibiotic resistance

tracheal aspirate

home mechanical ventilation

pediatricsantibiyotik direnci

trakeal aspirat

evde mekanik ventilasyon

pediatri

Issues

Article Details

Authors: Esra Akyüz Özkan | Demet Gür Vural

Publisher: Kirsehir Ahi Evran University

Main Topics: Klinik Tıp Bilimleri

Journal: Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.340-345

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001300274

pISSN: 2619-9203

Issues

Authors:

Esra Akyüz Özkan | Demet Gür Vural

Publisher:

Kirsehir Ahi Evran University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Ahi Evran Tıp Dergisi Vol.7 Issue 3, pp.340-345

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001300274

pISSN:

2619-9203