Effects of diltiazem on renal function

S. TOPÇU; S. SAĞIR; F. CANDAN; S. İÇAĞASIOĞLU; C. YILDIRIR

Article Details

Effects of diltiazem on renal function

Authors:

S. TOPÇU | S. SAĞIR | F. CANDAN | S. İÇAĞASIOĞLU | C. YILDIRIR

Publisher:

Marmara University

Main Topics:

Diseases

Journal:

Marmara Medical Journal 1995 Vol.8 Issue 1, pp.11-14

Document Type:

Article

Publication Date:

12/1994

Document Language:

Turkish

Document ID (Org No.):

2000547353

Frequency:

Monthly

eISSN:

1309-9469

pISSN:

1019-1941

Abstract:

 


We planned to investigate the effect of diltiazem on

urine volume, urine sodium (Na+) and potassium (K+) excretion and glomerular filtration rate (GFR). Twenty healthy men, aged between 23 and 36 (mean age: 29 ± 0.87) were examined. A double - blind placebo controlled study was completed by weekly intervals in 3 periods. In each period, first day no drug was given, the second day placebo, the third day diltiazem (30 mg or 60 mg) or placebo was given.

In the first 6 hour period following diltiazem 30 or 60 mg administration, increases in GFR (p0.05). In the next 18 hour period, we observed that diltiazem did not affect

the excretion of K+ urine volume and GFR (p> 0.05), but increased the excretion of Na+ (p<0.05).

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Article Details

Effects of diltiazem on renal function

Authors: S. TOPÇU | S. SAĞIR | F. CANDAN | S. İÇAĞASIOĞLU | C. YILDIRIR

Publisher: Marmara University

Main Topics: Diseases

Journal: Marmara Medical Journal 1995 Vol.8 Issue 1, pp.11-14

Document Type: Article

Publication Date: 12/1994

Document Language: Turkish

Document ID (Org No.): 2000547353

Frequency: Monthly

eISSN: 1309-9469

pISSN: 1019-1941

Issues

Authors:

S. TOPÇU | S. SAĞIR | F. CANDAN | S. İÇAĞASIOĞLU | C. YILDIRIR

Publisher:

Marmara University

Main Topics:

Diseases

Journal:

Marmara Medical Journal 1995 Vol.8 Issue 1, pp.11-14

Document Type:

Article

Publication Date:

12/1994

Document Language:

Turkish

Document ID (Org No.):

2000547353

Frequency:

Monthly

eISSN:

1309-9469

pISSN:

1019-1941