Cytomorphological findings in diagnosis of Warthin tumor

Fatma Fulya KÖYBAŞIOĞLU; Binnur ÖNAL; Ünsal HAN; Ayşegül ADABAĞ; Ahmet ŞAHPAZ

doi:https://doi.org/10.3906/sag-1901-215

Article Details

Cytomorphological findings in diagnosis of Warthin tumor

Authors:

Fatma Fulya KÖYBAŞIOĞLU | Binnur ÖNAL | Ünsal HAN | Ayşegül ADABAĞ | Ahmet ŞAHPAZ

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.148-154

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000749687

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

DOI:

https://doi.org/10.3906/sag-1901-215

Abstract:

 

Background/aim: To define the cytomorphologic findings leading to difficulties in diagnosis of Warthin tumors  WTs .Materials and methods: Forty-eight histopathologically diagnosed WT patients who had fine needle aspiration cytology preoperatively were  reevaluated  for  defining  the  presence  or  absence  of  lymphocytes,  oncocytic  cell  layer,  oncocytic  cell  papillae,  granular  debris  background,  mucoid  background,  macrophages,  polymorphonuclear  cells,  mast  cells,  squamous-like  cells,  atypical  vacuolated  cytoplasmic cells, and giant cells.Results: Forty-seven tumors were in the parotid gland and one in the submandibular gland. There were 37  77%  male and 11  23%  female  patients.  Cytopathologically  in  36  patients  the  diagnosis  was  benign  neoplasm   WT ;  in  6,  other  benign  entities;  and  in  6,  suspicious for malignancy. The main characteristic cytomorphologic features of WTs were as follows: 92% lymphoid cells, 83% oncocytic cell layers, and 67% granular debris background. These percentages were 67%, 17%, and 17% in the benign cytology group and 67%, 50%, and 17% in the suspicious for malignancy group, respectively.Conclusion: Absence or lack of main features of WTs with or without presence of squamous-like cells, vacuolated cytoplasmic cells, and inflammatory reaction may cause diagnostic dilemma. The presence of the mast cells accompanied by epithelial tissue was striking for WT diagnosis.

Article Details

Cytomorphological findings in diagnosis of Warthin tumor

Authors: Fatma Fulya KÖYBAŞIOĞLU | Binnur ÖNAL | Ünsal HAN | Ayşegül ADABAĞ | Ahmet ŞAHPAZ

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.148-154

Document Type: Article

Publication Date: 12/2019

Document Language: English

Document ID (Org No.): 2000749687

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

DOI: https://doi.org/10.3906/sag-1901-215

Issues

Authors:

Fatma Fulya KÖYBAŞIOĞLU | Binnur ÖNAL | Ünsal HAN | Ayşegül ADABAĞ | Ahmet ŞAHPAZ

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2020 Vol.50 Issue 1, pp.148-154

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000749687

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

DOI:

https://doi.org/10.3906/sag-1901-215