Blood Apelin-36 Level in Patients with Depression

Meltem Puşuroğlu; İlkay Bahçeci; Mehmet Baltacıoğlu; Bülent Bahçeci; Yunus Emre İbik

Article Details

Blood Apelin-36 Level in Patients with Depression

Authors:

Meltem Puşuroğlu | İlkay Bahçeci | Mehmet Baltacıoğlu | Bülent Bahçeci | Yunus Emre İbik

Publisher:

Recep Tayyip Erdoğan University

Main Topics:

Psikiyatri

Journal:

Rize Tıp Dergisi Vol.1 Issue 1, pp.1-8

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001313650

pISSN:

2791-7231

Keywords:

Abstract:

 Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability. Biochemical parameters that can be used in the diagnosis and follow-up of Major Depressive Disorders severity are important for clinicians. The aim of our study was to investigate blood apelin levels in patients with Major Depressive Disorder as a marker for disease severity and diagnosis. Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls. Hamilton Depression Scale was applied to the patient group. Blood apelin-36 levels were measured in both groups. Results: Plasma apelin-36 level was 0.3630.102 ngml min-max: 0.173-0.611 in the patient group and 1.1400.738 ngml min-max: 0.323-2.547 in the healthy control group. Blood apelin-36 level of the patient group was statistically significantly lower than that of the healthy control group p0.001. Conclusion: Blood apelin levels were found to be low in patients with Major Depressive Disorder. Apelin is an endogenous peptide with important physiological roles and looks promising as a biomarker. Its utility for the diagnosis and follow-up of mood disorders requires further investigation. In this respect, our research contributes to the literature.

 Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability. Biochemical parameters that can be used in the diagnosis and follow-up of Major Depressive Disorders severity are important for clinicians. The aim of our study was to investigate blood apelin levels in patients with Major Depressive Disorder as a marker for disease severity and diagnosis. Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls. Hamilton Depression Scale was applied to the patient group. Blood apelin-36 levels were measured in both groups. Results: Plasma apelin-36 level was 0.3630.102 ngml min-max: 0.173-0.611 in the patient group and 1.1400.738 ngml min-max: 0.323-2.547 in the healthy control group. Blood apelin-36 level of the patient group was statistically significantly lower than that of the healthy control group p0.001. Conclusion: Blood apelin levels were found to be low in patients with Major Depressive Disorder. Apelin is an endogenous peptide with important physiological roles and looks promising as a biomarker. Its utility for the diagnosis and follow-up of mood disorders requires further investigation. In this respect, our research contributes to the literature.

 Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability. Biochemical parameters that can be used in the diagnosis and follow-up of Major Depressive Disorders severity are important for clinicians. The aim of our study was to investigate blood apelin levels in patients with Major Depressive Disorder as a marker for disease severity and diagnosis. Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls. Hamilton Depression Scale was applied to the patient group. Blood apelin-36 levels were measured in both groups. Results: Plasma apelin-36 level was 0.3630.102 ngml min-max: 0.173-0.611 in the patient group and 1.1400.738 ngml min-max: 0.323-2.547 in the healthy control group. Blood apelin-36 level of the patient group was statistically significantly lower than that of the healthy control group p0.001. Conclusion: Blood apelin levels were found to be low in patients with Major Depressive Disorder. Apelin is an endogenous peptide with important physiological roles and looks promising as a biomarker. Its utility for the diagnosis and follow-up of mood disorders requires further investigation. In this respect, our research contributes to the literature.

 Abstract Aim: Major Depressive Disorder is an important health problem leading to significant disability. Biochemical parameters that can be used in the diagnosis and follow-up of Major Depressive Disorders severity are important for clinicians. The aim of our study was to investigate blood apelin levels in patients with Major Depressive Disorder as a marker for disease severity and diagnosis. Materials and Methods: The study included 30 patients diagnosed with Major Depressive Disorder and 31 healthy controls. Hamilton Depression Scale was applied to the patient group. Blood apelin-36 levels were measured in both groups. Results: Plasma apelin-36 level was 0.3630.102 ngml min-max: 0.173-0.611 in the patient group and 1.1400.738 ngml min-max: 0.323-2.547 in the healthy control group. Blood apelin-36 level of the patient group was statistically significantly lower than that of the healthy control group p0.001. Conclusion: Blood apelin levels were found to be low in patients with Major Depressive Disorder. Apelin is an endogenous peptide with important physiological roles and looks promising as a biomarker. Its utility for the diagnosis and follow-up of mood disorders requires further investigation. In this respect, our research contributes to the literature.

Article Details

Blood Apelin-36 Level in Patients with Depression

Authors:

Meltem Puşuroğlu | İlkay Bahçeci | Mehmet Baltacıoğlu | Bülent Bahçeci | Yunus Emre İbik

Publisher:

Recep Tayyip Erdoğan University

Main Topics:

Psikiyatri

Journal:

Rize Tıp Dergisi Vol.1 Issue 1, pp.1-8

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001313650

pISSN:

2791-7231

Depression

Apelin

Mood Disorders

Issues

Article Details

Blood Apelin-36 Level in Patients with Depression

Authors: Meltem Puşuroğlu | İlkay Bahçeci | Mehmet Baltacıoğlu | Bülent Bahçeci | Yunus Emre İbik

Publisher: Recep Tayyip Erdoğan University

Main Topics: Psikiyatri

Journal: Rize Tıp Dergisi Vol.1 Issue 1, pp.1-8

Document Type: Article

Publication Date: 3/2024

Document Language: English

Document ID (Org No.): 2001313650

pISSN: 2791-7231

Depression

Apelin

Mood Disorders

Issues

Authors:

Meltem Puşuroğlu | İlkay Bahçeci | Mehmet Baltacıoğlu | Bülent Bahçeci | Yunus Emre İbik

Publisher:

Recep Tayyip Erdoğan University

Main Topics:

Psikiyatri

Journal:

Rize Tıp Dergisi Vol.1 Issue 1, pp.1-8

Document Type:

Article

Publication Date:

3/2024

Document Language:

English

Document ID (Org No.):

2001313650

pISSN:

2791-7231