Ultrastructure of rat umbilical cord stroma-derived mesenchymal stem cells

Ahmet CEYLAN; Özge ÖZGENÇ; Korhan ALTUNBAŞ; Petek KORKUSUZ; Asuman ÖZEN

Article Details

Ultrastructure of rat umbilical cord stroma-derived mesenchymal stem cells

Authors:

Ahmet CEYLAN | Özge ÖZGENÇ | Korhan ALTUNBAŞ | Petek KORKUSUZ | Asuman ÖZEN

Publisher:

TUBITAK

Journal:

Turkish Journal of Veterinary and Animal Sciences 2017 Vol.41 Issue 4, pp.464-470

Document Type:

Article

Publication Date:

8/2017

Document Language:

English

Document ID (Org No.):

2000764875

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128

Abstract:

 

 
                         Being multipotent progenitor cells, mesenchymal stem cells continue to attract attention as a promising tool for cell-based therapy and tissue engineering. However, research on the ultrastructure of these cells is rather scarce. This study was aimed at the investigation of the transmission electron microscopic ultrastructure and morphology of mesenchymal stem cells isolated from the stroma of rat umbilical cord using the explant culture method. At the end of the third passage, some of the cells isolated from the stroma of the umbilical cord were harvested for electron microscopic examination. The remaining cells were induced for osteogenic, chondrogenic, and adipogenic differentiation. On the basis of the results obtained, it was concluded that mesenchymal stem cells derived from the stroma of the umbilical cord display morphological features similar to those of other types of mesenchymal stem cells and can be used as an alternative cell source in cell-based therapy owing to the advantages they offer.

Article Details

Ultrastructure of rat umbilical cord stroma-derived mesenchymal stem cells

Authors: Ahmet CEYLAN | Özge ÖZGENÇ | Korhan ALTUNBAŞ | Petek KORKUSUZ | Asuman ÖZEN

Publisher: TUBITAK

Journal: Turkish Journal of Veterinary and Animal Sciences 2017 Vol.41 Issue 4, pp.464-470

Document Type: Article

Publication Date: 8/2017

Document Language: English

Document ID (Org No.): 2000764875

Frequency: Bimonthly

eISSN: 1303-6181

pISSN: 1300-0128

Issues

Authors:

Ahmet CEYLAN | Özge ÖZGENÇ | Korhan ALTUNBAŞ | Petek KORKUSUZ | Asuman ÖZEN

Publisher:

TUBITAK

Journal:

Turkish Journal of Veterinary and Animal Sciences 2017 Vol.41 Issue 4, pp.464-470

Document Type:

Article

Publication Date:

8/2017

Document Language:

English

Document ID (Org No.):

2000764875

Frequency:

Bimonthly

eISSN:

1303-6181

pISSN:

1300-0128