Efficacy of Intravenous Iron Therapy in Female Patients with Iron Deficiency Anemia

Sevgi Güneş; Naci Ömer Alayunt; Osman Özüdoğru

Article Details

Efficacy of Intravenous Iron Therapy in Female Patients with Iron Deficiency Anemia

Authors:

Sevgi Güneş | Naci Ömer Alayunt | Osman Özüdoğru

Publisher:

Bingol University

Main Topics:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Journal:

Türk Doğa ve Fen Dergisi Vol.12 Issue 4, pp.134-138

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307726

pISSN:

2149-6366

Keywords:

Abstract:

 Abstract: In this study, it was aimed to show the efficacy of intravenous IV ferric carboxymaltose treatment for iron deficiency anemia IDA, which is a public health problem due to its high prevalence in the world and in Turkey. Since it is the first study in the region, its importance is increasing even more. Eighty female diagnosed with IDA and treated with IV iron carboxymaltose, who applied to Siirt Training and Research Hospital Internal Diseases Polyclinics between June 2018 and September 2019, were included in the study. After obtaining voluntary consent of female patients, biochemical data of pre- and post-treatment were included in the study retrospectively. After treatment, hemoglobin HGB, hematocrit HTC, mean cell volume MCV, ferritin, iron and B12 values increased statistically p0.05. In addition, platelet PLT, total iron binding capacity TIBC and folate values were statistically significantly lower p0.05. The study is important in terms of revealing the female IDA profile in the region and showing the positive results of IV iron therapy data. It is thought that the study can be a guide in finding solutions to irrational drug use, prolongation of the treatment period and high expenditures while creating IDA treatment protocols.

 Abstract: In this study, it was aimed to show the efficacy of intravenous IV ferric carboxymaltose treatment for iron deficiency anemia IDA, which is a public health problem due to its high prevalence in the world and in Turkey. Since it is the first study in the region, its importance is increasing even more. Eighty female diagnosed with IDA and treated with IV iron carboxymaltose, who applied to Siirt Training and Research Hospital Internal Diseases Polyclinics between June 2018 and September 2019, were included in the study. After obtaining voluntary consent of female patients, biochemical data of pre- and post-treatment were included in the study retrospectively. After treatment, hemoglobin HGB, hematocrit HTC, mean cell volume MCV, ferritin, iron and B12 values increased statistically p0.05. In addition, platelet PLT, total iron binding capacity TIBC and folate values were statistically significantly lower p0.05. The study is important in terms of revealing the female IDA profile in the region and showing the positive results of IV iron therapy data. It is thought that the study can be a guide in finding solutions to irrational drug use, prolongation of the treatment period and high expenditures while creating IDA treatment protocols.

 Abstract: In this study, it was aimed to show the efficacy of intravenous IV ferric carboxymaltose treatment for iron deficiency anemia IDA, which is a public health problem due to its high prevalence in the world and in Turkey. Since it is the first study in the region, its importance is increasing even more. Eighty female diagnosed with IDA and treated with IV iron carboxymaltose, who applied to Siirt Training and Research Hospital Internal Diseases Polyclinics between June 2018 and September 2019, were included in the study. After obtaining voluntary consent of female patients, biochemical data of pre- and post-treatment were included in the study retrospectively. After treatment, hemoglobin HGB, hematocrit HTC, mean cell volume MCV, ferritin, iron and B12 values increased statistically p0.05. In addition, platelet PLT, total iron binding capacity TIBC and folate values were statistically significantly lower p0.05. The study is important in terms of revealing the female IDA profile in the region and showing the positive results of IV iron therapy data. It is thought that the study can be a guide in finding solutions to irrational drug use, prolongation of the treatment period and high expenditures while creating IDA treatment protocols.

 Bu çalışmada, dünyada ve Türkiyede prevalansının yüksek olması nedeniyle bir halk sağlığı sorunu olan demir eksikliği anemisinde DEA intravenöz İV ferrik karboksimaltoz tedavisinin etkinliğinin gösterilmesi amaçlandı. Bölgedeki ilk çalışma olması nedeniyle önemi daha da artmaktadır. Haziran 2018-Eylül 2019 tarihleri arasında Siirt Eğitim ve Araştırma Hastanesi İç Hastalıkları Polikliniğine başvuran, DEA tanılı ve İV demir karboksimaltoz tedavisi uygulanan 80 kadın çalışmaya dahil edildi. Kadın hastalardan gönüllü onam alındıktan sonra tedavi öncesi ve sonrası biyokimyasal veriler retrospektif olarak çalışmaya dahil edildi. Tedavi sonrası hemoglobin HGB, hematokrit HTC, ortalama hücre hacmi MCV, ferritin, demir ve B12 değerleri istatistiksel olarak arttı p0.05. p0.05. Ayrıca trombosit PLT, toplam demir bağlama kapasitesi TIBC ve folat değerleri istatistiksel olarak anlamlı derecede düşüktü p0.05. Çalışma bölgedeki kadın DEA profilini ortaya koyması ve İV demir tedavisi verilerinin olumlu sonuçlarını göstermesi açısından önemlidir. Çalışmanın DEA tedavi protokolleri oluşturulurken akılcı olmayan ilaç kullanımına, tedavi süresinin uzamasına ve yüksek tedavi harcamalarına çözüm bulunmasında yol gösterici olabileceği düşünülmektedir.

Article Details

Efficacy of Intravenous Iron Therapy in Female Patients with Iron Deficiency Anemia

Authors:

Sevgi Güneş | Naci Ömer Alayunt | Osman Özüdoğru

Publisher:

Bingol University

Main Topics:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Journal:

Türk Doğa ve Fen Dergisi Vol.12 Issue 4, pp.134-138

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307726

pISSN:

2149-6366

Iron deficiency anemia

Iron replacement

Intravenous carboxymaltose

Serum TIBC

Serum folateDemir eksikliği anemisi

Demir replasmanı

İntravenoz karboksimaltoz

Serum TIBC

Serum folat

Issues

Article Details

Authors: Sevgi Güneş | Naci Ömer Alayunt | Osman Özüdoğru

Publisher: Bingol University

Main Topics: Sağlık Hizmetleri ve Sistemleri (Diğer)

Journal: Türk Doğa ve Fen Dergisi Vol.12 Issue 4, pp.134-138

Document Type: Article

Publication Date: 12/2023

Document Language: English

Document ID (Org No.): 2001307726

pISSN: 2149-6366

Issues

Authors:

Sevgi Güneş | Naci Ömer Alayunt | Osman Özüdoğru

Publisher:

Bingol University

Main Topics:

Sağlık Hizmetleri ve Sistemleri (Diğer)

Journal:

Türk Doğa ve Fen Dergisi Vol.12 Issue 4, pp.134-138

Document Type:

Article

Publication Date:

12/2023

Document Language:

English

Document ID (Org No.):

2001307726

pISSN:

2149-6366