COMPARISON OF THE EFFECTIVENESS OF CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE ON SURGICAL SITE INFECTION IN PRIMARY TOTAL KNEE ARTHROPLASTY

Selda Urfa; Büşra Saygın; Yasemin Cicibaş; Bekir Ballı; Dudu Ayşe Gülkan; Süleyman Akkuzu; Fatih İnci

Article Details

COMPARISON OF THE EFFECTIVENESS OF CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE ON SURGICAL SITE INFECTION IN PRIMARY TOTAL KNEE ARTHROPLASTY

Authors:

Selda Urfa | Büşra Saygın | Yasemin Cicibaş | Bekir Ballı | Dudu Ayşe Gülkan | Süleyman Akkuzu | Fatih İnci

Publisher:

Süleyman Demirel University

Main Topics:

Clinical Sciences | Health Care Administration

Journal:

Medical Journal of Süleyman Demirel University Vol.30 Issue 3, pp.372-379

Document Type:

Article

Publication Date:

9/2023

Document Language:

Turkish

Document ID (Org No.):

2001299101

pISSN:

1300-7416

Keywords:

Abstract:

 Objective Patient skin is a major source for pathogenic microorganisms. Before surgery, it is a standard method to clean the skin with antiseptics and remove these pathogens from the surgical area. Chlorhexidine gluconate CG and Povidone iodine PI are two different antiseptics recommended for this purpose. Although there are many studies showing the effectiveness of these antiseptics in contaminated surgeries, studies reporting their effectiveness in clean surgeries are limited. In this study, it was aimed to compare the effectiveness of chlorhexidine gluconate on surgical site infection with povidone iodine in primary total knee arthroplasty, which is a clean surgery. Material and Method The data of a total of 245 primary total knee arthroplasty patients who used CG 110 patients and PI 135 patients for surgical site skin cleansing were analyzed. The patients were divided into 2 groups as KG group and PI group according to the antiseptic used. Demographic characteristics of the groups were similar p0.05. In the KG group, swab samples taken from the surgical field before and after surgery were microbiologically examined and the immediate efficacy of chlorhexidine gluconate on surgical site asepsis was evaluated as the primary outcome of the study. Complication of infection in the surgical field in both groups; superficial infection minor complication and deep infection major complication were recorded. As a secondary outcome of the study, surgical site complications were compared between both groups. Results At least one pathogenic microorganism was grown in all swab samples taken from the surgical area before the use of CG, while there was no growth in any of the swab samples taken after using CG. Complications of the surgical field in the KG and PI groups, respectively; minor complications 4.54 vs. 5.18 and major complications 0.9 vs. 1.8 were found. There was no statistically significant difference between the groups in terms of minor and major complications p0.05. In the primary result of the study, when chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical field, and as a secondary result, there is no difference between the groups in the comparison of chlorhexidine gluconate with povidone iodine in terms of its effectiveness in surgical site infection. Conclusion This study is one of the rare studies evaluating the efficacy of antiseptics in primary total knee arthroplasty, which is a clean surgery. When chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical area and is as effective as povidone iodine in preventing surgical site infection.

 Objective Patient skin is a major source for pathogenic microorganisms. Before surgery, it is a standard method to clean the skin with antiseptics and remove these pathogens from the surgical area. Chlorhexidine gluconate CG and Povidone iodine PI are two different antiseptics recommended for this purpose. Although there are many studies showing the effectiveness of these antiseptics in contaminated surgeries, studies reporting their effectiveness in clean surgeries are limited. In this study, it was aimed to compare the effectiveness of chlorhexidine gluconate on surgical site infection with povidone iodine in primary total knee arthroplasty, which is a clean surgery. Material and Method The data of a total of 245 primary total knee arthroplasty patients who used CG 110 patients and PI 135 patients for surgical site skin cleansing were analyzed. The patients were divided into 2 groups as KG group and PI group according to the antiseptic used. Demographic characteristics of the groups were similar p0.05. In the KG group, swab samples taken from the surgical field before and after surgery were microbiologically examined and the immediate efficacy of chlorhexidine gluconate on surgical site asepsis was evaluated as the primary outcome of the study. Complication of infection in the surgical field in both groups; superficial infection minor complication and deep infection major complication were recorded. As a secondary outcome of the study, surgical site complications were compared between both groups. Results At least one pathogenic microorganism was grown in all swab samples taken from the surgical area before the use of CG, while there was no growth in any of the swab samples taken after using CG. Complications of the surgical field in the KG and PI groups, respectively; minor complications 4.54 vs. 5.18 and major complications 0.9 vs. 1.8 were found. There was no statistically significant difference between the groups in terms of minor and major complications p0.05. In the primary result of the study, when chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical field, and as a secondary result, there is no difference between the groups in the comparison of chlorhexidine gluconate with povidone iodine in terms of its effectiveness in surgical site infection. Conclusion This study is one of the rare studies evaluating the efficacy of antiseptics in primary total knee arthroplasty, which is a clean surgery. When chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical area and is as effective as povidone iodine in preventing surgical site infection.

 Objective Patient skin is a major source for pathogenic microorganisms. Before surgery, it is a standard method to clean the skin with antiseptics and remove these pathogens from the surgical area. Chlorhexidine gluconate CG and Povidone iodine PI are two different antiseptics recommended for this purpose. Although there are many studies showing the effectiveness of these antiseptics in contaminated surgeries, studies reporting their effectiveness in clean surgeries are limited. In this study, it was aimed to compare the effectiveness of chlorhexidine gluconate on surgical site infection with povidone iodine in primary total knee arthroplasty, which is a clean surgery. Material and Method The data of a total of 245 primary total knee arthroplasty patients who used CG 110 patients and PI 135 patients for surgical site skin cleansing were analyzed. The patients were divided into 2 groups as KG group and PI group according to the antiseptic used. Demographic characteristics of the groups were similar p0.05. In the KG group, swab samples taken from the surgical field before and after surgery were microbiologically examined and the immediate efficacy of chlorhexidine gluconate on surgical site asepsis was evaluated as the primary outcome of the study. Complication of infection in the surgical field in both groups; superficial infection minor complication and deep infection major complication were recorded. As a secondary outcome of the study, surgical site complications were compared between both groups. Results At least one pathogenic microorganism was grown in all swab samples taken from the surgical area before the use of CG, while there was no growth in any of the swab samples taken after using CG. Complications of the surgical field in the KG and PI groups, respectively; minor complications 4.54 vs. 5.18 and major complications 0.9 vs. 1.8 were found. There was no statistically significant difference between the groups in terms of minor and major complications p0.05. In the primary result of the study, when chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical field, and as a secondary result, there is no difference between the groups in the comparison of chlorhexidine gluconate with povidone iodine in terms of its effectiveness in surgical site infection. Conclusion This study is one of the rare studies evaluating the efficacy of antiseptics in primary total knee arthroplasty, which is a clean surgery. When chlorhexidine gluconate is used in primary total knee arthroplasty, it creates complete asepsis in the surgical area and is as effective as povidone iodine in preventing surgical site infection.

 Amaç Hasta cildi patojen mikroorganizmalar için majör bir kaynaktır. Cerrahi öncesinde, cilt temizliğinin antiseptiklerle yapılarak bu patojenlerin cerrahi alandan uzaklaştırılması standart bir yöntemdir. Klorheksidin glukonat KG ve Povidon iyot Pİ bu amaç için önerilen iki farklı antiseptiktir. Bu antiseptiklerin kontamine cerrahilerdeki etkinliğini gösteren çok sayıda çalışma olmasına rağmen, temiz cerrahilerdeki etkinliğini bildiren çalışmalar kısıtlıdır. Bu çalışmada, temiz cerrahi olan primer total diz artroplastisinde klorheksidin glukonatın cerrahi alan enfeksiyonuna etkinliğinin povidon iyot ile karşılaştırılması amaçlandı. Gereç ve Yöntem Cerrahi alan cilt temizliğinde KG 110 hasta ve Pİ 135 hasta kullanılan toplam 245 primer total diz artroplastisi hastasının verileri incelendi. Hastalar kullanılan antiseptiğe göre KG grubu ve Pİ grubu olarak 2 gruba ayrıldı. Grupların demografik özellikleri benzerdi p0,05. KG grubunda, cerrahi alandan cerrahi öncesi ve sonrasında alınan sürüntü örnekleri mikrobiyolojik olarak incelendi ve çalışmanın birincil sonucu olarak KGnin cerrahi alan asepsisine anlık etkinliği değerlendirildi. Her iki grupta cerrahi alanda gelişen enfeksiyon komplikasyonu; yüzeyel enfeksiyon minör komplikasyon ve derin enfeksiyon majör komplikasyon olarak kaydedildi. Çalışmanın ikincil sonucu olarak cerrahi alan komplikasyonları her iki grup arasında karşılaştırıldı. Bulgular KG kullanılmadan önce cerrahi alandan alınan sürüntü örneklerinin hepsinde en az bir patojen mikroorganizma ürerken, KG kullanıldıktan sonra alınan sürüntü örneklerinin hiçbirinde üreme olmadı. KG ve Pİ grubunda cerrahi alan komplikasyonları sırasıyla; minör komplikasyonlar 4,54 ve 5,18 ve majör komplikasyonlar 0,9 ve 1,8 olarak bulundu. Minör ve majör komplikasyonlar açısından gruplar arasında istatistiksel anlamlı fark bulunmadı p0,05. Çalışmanın birincil sonucunda, primer total diz artroplastisinde klorheksidin glukonat kullanıldığında cerrahi alanda tam bir asepsi oluşturmaktadır ve ikincil sonuç olarak cerrahi alan enfeksiyonuna etkinliği açısından klorheksidin glukonatın povidon iyot ile karşılaştırılmasında gruplar arasında fark olmadığı sonucu elde edildi. Sonuç Bu çalışma temiz cerrahi olan primer total diz artroplastisinde antiseptiklerin etkinliğini değerlendiren nadir çalışmalardan biridir. Primer total diz artroplastisinde klorheksidin glukonat kullanıldığında cerrahi alanda tam bir asepsi oluşturmaktadır ve cerrahi alan enfeksiyonunu önlemede povidon iyot gibi etkindir.

Article Details

COMPARISON OF THE EFFECTIVENESS OF CHLORHEXIDINE GLUCONATE AND POVIDONE IODINE ON SURGICAL SITE INFECTION IN PRIMARY TOTAL KNEE ARTHROPLASTY

Authors:

Selda Urfa | Büşra Saygın | Yasemin Cicibaş | Bekir Ballı | Dudu Ayşe Gülkan | Süleyman Akkuzu | Fatih İnci

Publisher:

Süleyman Demirel University

Main Topics:

Clinical Sciences | Health Care Administration

Journal:

Medical Journal of Süleyman Demirel University Vol.30 Issue 3, pp.372-379

Document Type:

Article

Publication Date:

9/2023

Document Language:

Turkish

Document ID (Org No.):

2001299101

pISSN:

1300-7416

Asepsis

Chlorhexidine gluconate

Povidone iodine

Primary total knee arthroplasty

Surgical site infectionAsepsi

Cerrahi alan enfeksiyonu

Klorheksidin glukonat

Povidon iyot

Primer total diz artroplastisi

Issues

Article Details

Authors: Selda Urfa | Büşra Saygın | Yasemin Cicibaş | Bekir Ballı | Dudu Ayşe Gülkan | Süleyman Akkuzu | Fatih İnci

Publisher: Süleyman Demirel University

Main Topics: Clinical Sciences | Health Care Administration

Journal: Medical Journal of Süleyman Demirel University Vol.30 Issue 3, pp.372-379

Document Type: Article

Publication Date: 9/2023

Document Language: Turkish

Document ID (Org No.): 2001299101

pISSN: 1300-7416

Issues

Authors:

Selda Urfa | Büşra Saygın | Yasemin Cicibaş | Bekir Ballı | Dudu Ayşe Gülkan | Süleyman Akkuzu | Fatih İnci

Publisher:

Süleyman Demirel University

Main Topics:

Clinical Sciences | Health Care Administration

Journal:

Medical Journal of Süleyman Demirel University Vol.30 Issue 3, pp.372-379

Document Type:

Article

Publication Date:

9/2023

Document Language:

Turkish

Document ID (Org No.):

2001299101

pISSN:

1300-7416