CEREBROSPINAL FLUID (CSF) IL-17A, IL-17F, IL-34 AND CXCL-13 LEVELS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS/MND) PATIENTS

Hayriye ORALLAR; Şeyda KARABÖRK; Bihter Gökçe BOZAT; Şule AYDIN TÜRKOĞLU

Article Details

CEREBROSPINAL FLUID (CSF) IL-17A, IL-17F, IL-34 AND CXCL-13 LEVELS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS/MND) PATIENTS

Authors:

Hayriye ORALLAR | Şeyda KARABÖRK | Bihter Gökçe BOZAT | Şule AYDIN TÜRKOĞLU

Publisher:

E-Journal of New World Sciences Academy

Main Topics:

Promotion of health

Journal:

Medical Sciences 2019 Vol.14 Issue 3, pp.154-162

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

2000827227

Frequency:

Quarterly

eISSN:

1308-7312

Keywords:

Abstract:

 


In this study, our clinic follow-up ALS/MND diagnose the cerebrospinal fluid of patients (CSF), IL-17A, IL-17F, IL-34 cytokines and CXCL-13 chemokine to evaluate the levels. that were determined by ELISA. In our study, significantly higher in the patient group and the proinflammatory cytokine, IL-17A and IL-17F of endothelial cells, fibroblasts and also known to be expressed in neurones. However, CXCL13 level is considered among the patient group and the control group was not statistically significant difference. IL-34 also to be increased when compared to the patient group (n=4) than the control group (n=6), a recently described cytokine due to the IL-34 Th17 with modulating immune pathogenesis and immune with cytokines released from cells in a short time to be involved ALS/MND such as rare as to be made further studies for the diagnosis of a disease to a powerful new biomarker may and science has been suggested to contribute in this respect. 

.

 


     In this study, our clinic follow-up ALS/MND diagnose
the cerebrospinal fluid of patients (CSF), IL-17A, IL-17F, IL-34 cytokines and
CXCL-13 chemokine to evaluate the levels. that were determined by ELISA. In our
study, significantly higher in the patient group and the proinflammatory
cytokine, IL-17A and IL-17F of endothelial cells, fibroblasts and also known to
be expressed in neurones. However, CXCL-13 level is considered among the
patient group and the control group was not statistically significant difference.
IL-34 also to be increased when compared to the patient group (n=4) than the
control group (n=6), a recently described cytokine due to the IL-34 Th17 with
modulating immune pathogenesis and immune with cytokines released from cells in
a short time to be involved ALS/MND such as rare as to be made further studies
for the diagnosis of a disease to a powerful new biomarker may and science has
been suggested to contribute in this respect.




.

Article Details

CEREBROSPINAL FLUID (CSF) IL-17A, IL-17F, IL-34 AND CXCL-13 LEVELS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS/MND) PATIENTS

Authors:

Hayriye ORALLAR | Şeyda KARABÖRK | Bihter Gökçe BOZAT | Şule AYDIN TÜRKOĞLU

Publisher:

E-Journal of New World Sciences Academy

Main Topics:

Promotion of health

Journal:

Medical Sciences 2019 Vol.14 Issue 3, pp.154-162

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

2000827227

Frequency:

Quarterly

eISSN:

1308-7312

ALS/MND

IL-17

IL-34

CXCL-13

Patient

Issues

Article Details

CEREBROSPINAL FLUID (CSF) IL-17A, IL-17F, IL-34 AND CXCL-13 LEVELS IN AMYOTROPHIC LATERAL SCLEROSIS (ALS/MND) PATIENTS

Authors: Hayriye ORALLAR | Şeyda KARABÖRK | Bihter Gökçe BOZAT | Şule AYDIN TÜRKOĞLU

Publisher: E-Journal of New World Sciences Academy

Main Topics: Promotion of health

Journal: Medical Sciences 2019 Vol.14 Issue 3, pp.154-162

Document Type: Article

Publication Date: 7/2019

Document Language: English

Document ID (Org No.): 2000827227

Frequency: Quarterly

eISSN: 1308-7312

ALS/MND

IL-17

IL-34

CXCL-13

Patient

Issues

Authors:

Hayriye ORALLAR | Şeyda KARABÖRK | Bihter Gökçe BOZAT | Şule AYDIN TÜRKOĞLU

Publisher:

E-Journal of New World Sciences Academy

Main Topics:

Promotion of health

Journal:

Medical Sciences 2019 Vol.14 Issue 3, pp.154-162

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

2000827227

Frequency:

Quarterly

eISSN:

1308-7312