The Relationship between Clinico-Pathological Variables and Axillary Lymph Node Status in Breast Cancer in a Single Cancer Center in Jordan

Majdi A. Al Soudi; Ali D. Al Eboos; Omar M. Abu Al-Aish; Hytham S. Erbaihat; Raed Y. Al Jarrah

doi:10.12816/0011363

Article Details

The Relationship between Clinico-Pathological Variables and Axillary Lymph Node Status in Breast Cancer in a Single Cancer Center in Jordan

Authors:

Majdi A. Al Soudi | Ali D. Al Eboos | Omar M. Abu Al-Aish | Hytham S. Erbaihat | Raed Y. Al Jarrah

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2015 Vol.22 Issue 2, pp.35-40

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

64145

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0011363

Descriptors:

Keywords:

Abstract:

 Objective: To determine the relationship between axillary lymph node involvement and clinico-pathological variables in a single cancer center in Jordan.
Methods: This retrospective study was conducted in Al-Hussein Hospital in Amman from Jan 2011 till Jan 2013. This study revised the histopathology reports of 204 patients who all underwent modified radical mastectomy for invasive breast cancer. Various clinico-pathological factors of age, estrogen/progesterone receptor status, tumor size, histological type and grade were statistically correlated with lymph node involvement using contingency tables and P values.
Results: Axillary lymph node involvement was noted in 152 (74.5%) with an average of five nodesinvolved (range 1-41). Mean age was 51.3 years. Around eighty percent of patients were above 40 yearsold and had involved lymph node whereas only twenty percent were below 40 years with involvedlymph node. Average tumor size was 3.5cm with 67.1% between 2-5cm (T2). The most common tumortype and grade was invasive ductal carcinoma (NOS) (170 patients (83.3%)) and grade 2 (119 patient(58.3%)). The Majority of tumors were both ER and PR positive 75%. Tumor grade, size andhistological type significantly correlated with lymph node involvement whereas age and receptor statushad no significant correlation.
Conclusion: The majority of patients in our centre present with node positive breast cancer. In a Jordanian population, as has been demonstrated in the world literature, there is a statistically significant relation between axillary lymph node involvement and tumor, size, grade and type and that age is not an independent predictor for node positivist.

Article Details

The Relationship between Clinico-Pathological Variables and Axillary Lymph Node Status in Breast Cancer in a Single Cancer Center in Jordan

Authors:

Majdi A. Al Soudi | Ali D. Al Eboos | Omar M. Abu Al-Aish | Hytham S. Erbaihat | Raed Y. Al Jarrah

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2015 Vol.22 Issue 2, pp.35-40

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

64145

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0011363

Descriptors:

AXILLARY NODE

LYMPH

LYMPHATIC DISEASES

BREAST CANCER

PATHOLOGY

PROGNOSTIC FEATURES

Axillary Metastasis

Breast Cancer

Lymph Node Involvement

Prognostic Factors

Issues

Article Details

Authors: Majdi A. Al Soudi | Ali D. Al Eboos | Omar M. Abu Al-Aish | Hytham S. Erbaihat | Raed Y. Al Jarrah

Publisher: Jordanian Medical services - Jordanian Armed Forces

Main Topics: Medicine

Journal: Journal of the Royal Medical Services 2015 Vol.22 Issue 2, pp.35-40

Document Type: Article

Publication Date: 6/2015

Document Language: English

Document ID (Org No.): 64145

Frequency: Quarterly

eISSN: 20788711

pISSN: 20788703

DOI: 10.12816/0011363

Descriptors:

Issues

Authors:

Majdi A. Al Soudi | Ali D. Al Eboos | Omar M. Abu Al-Aish | Hytham S. Erbaihat | Raed Y. Al Jarrah

Publisher:

Jordanian Medical services - Jordanian Armed Forces

Main Topics:

Medicine

Journal:

Journal of the Royal Medical Services 2015 Vol.22 Issue 2, pp.35-40

Document Type:

Article

Publication Date:

6/2015

Document Language:

English

Document ID (Org No.):

64145

Frequency:

Quarterly

eISSN:

20788711

pISSN:

20788703

DOI:

10.12816/0011363