Importance of prognostic nutritional index in on-pump coronary artery bypass graft surgery

Arif GUCU

doi:https://doi.org/10.18621/eurj.947388

Article Details

Importance of prognostic nutritional index in on-pump coronary artery bypass graft surgery

Authors:

Arif GUCU

Publisher:

Prusa Medical Publishing

Main Topics:

Diseases

Journal:

The European Research Journal 2021 Vol.7 Issue 4, pp.432-439

Document Type:

Article

Publication Date:

7/2021

Document Language:

English

Document ID (Org No.):

2000661924

Frequency:

Bimonthly

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.947388

Abstract:

 


Objectives: A simple and appropriate risk index is still required to show the patient's nutritional status undergoing coronary artery bypass graft (CABG) surgery. This study aimed to evaluate the Prognostic Nutritional Index (PNI) value as a predictor of in-hospital mortality in patients undergoing CABG surgery. 

Methods: In this study, we scanned the medical data of 742 patients’ who underwent on-pump CABG surgery retrospectively. Patients' were divided into two groups based on the PNI cut-off value (high-risk group, PNI < 45.85, n = 230; low-risk group, PNI ≥ 45.85, n = 512). 

Results: To analyze the factors affecting in-hospital mortality in the postoperative period, univariate and multivariate logistic regression analysis was performed. In univariate analysis, advanced age (Odds ratio (OR): 1.219, 95% confidence interval (CI): 1.194-2.669, p < 0.001), left ventricular ejection fraction (LVEF) (OR: 3.471, 95% CI: 2.854-6.927, p < 0.001), total perfusion time (OR: 0.876, 95% CI: 0.690-0.954, p = 0.012), intra-aortic balloon pump (IABP) use (OR: 2.148, 95% CI: 1.394-2.889, p = 0.002), preoperative high creatinine (OR: 1.229, 95% CI: 1.066-2.118, p = 0.019), low lymphocyte count (OR: 0.879, 95% CI: 0.789-0.945, p = 0.017), low albumin (OR: 1.682, 95% CI: 1.433-2.765, p = 0.003), high C-reactive protein (CRP) (OR: 1.0.790, 95% CI: 0.678-0.927, p = 0.042) and low PNI (OR: 1.290, 95% CI: 1.119-1.654, p < 0.001) were correlated with the postoperative mortality. In multivariate logistic regression analysis, advanced age (OR: 1.145, 95% CI: 1.110-1.938, p = 0.017), LVEF (OR: 2.916, 95% CI: 1.768-4.928, p < 0.001), IABP use (OR: 1.880, 95% CI: 1.350-2.554, p = 0.032) and PNI (OR: 0.932, 95% CI: 0.889-0.978, p = 0.004) were independent predictors of mortality. 

Conclusions: In on-pump CABG surgery, postoperative mortality is associated with low preoperative PNI, and can be a useful and suitable parameter for preoperative risk evaluation.

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Article Details

Importance of prognostic nutritional index in on-pump coronary artery bypass graft surgery

Authors: Arif GUCU

Publisher: Prusa Medical Publishing

Main Topics: Diseases

Journal: The European Research Journal 2021 Vol.7 Issue 4, pp.432-439

Document Type: Article

Publication Date: 7/2021

Document Language: English

Document ID (Org No.): 2000661924

Frequency: Bimonthly

eISSN: 2149-3189

DOI: https://doi.org/10.18621/eurj.947388

Issues

Authors:

Arif GUCU

Publisher:

Prusa Medical Publishing

Main Topics:

Diseases

Journal:

The European Research Journal 2021 Vol.7 Issue 4, pp.432-439

Document Type:

Article

Publication Date:

7/2021

Document Language:

English

Document ID (Org No.):

2000661924

Frequency:

Bimonthly

eISSN:

2149-3189

DOI:

https://doi.org/10.18621/eurj.947388