THE EFFECT OF MENOPAUSE ON NADPH OXIDASE LEVELS AFTER NON-SURGICAL PERIODONTAL TREATMENTS ON PATIENTS WITH PERIODONTITIS

Mahmut KAYAALTI; Vildan BOSTANCI; Halef DOGAN

doi:https://doi.org/10.7126/cumudj.1000295

Article Details

THE EFFECT OF MENOPAUSE ON NADPH OXIDASE LEVELS AFTER NON-SURGICAL PERIODONTAL TREATMENTS ON PATIENTS WITH PERIODONTITIS

Authors:

Mahmut KAYAALTI | Vildan BOSTANCI | Halef DOGAN

Main Topics:

Promotion of health

Journal:

Cumhuriyet Dental Journal 2021 Vol.24 Issue 4, pp.415-426

Document Type:

Article

Publication Date:

1/2022

Document Language:

English

Document ID (Org No.):

2000734159

DOI:

https://doi.org/10.7126/cumudj.1000295

Abstract:

 

ABSTRACT
Objectives: This study evaluated the clinical parameters [ plaque index (PI), gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL) ] and the levels of Nadph Oxidase (NOX-1)  in gingival crevicular fluid (GCF) samples of pre-menopausal and post-menopausal periodontally healthy and periodontitis patients.
Materials and Methods: Study included pre-menopausal periodontitis 15, post-menopausal periodontitis 15, pre-menopausal periodontally healthy 15 and post-menopausal periodontally healthy 15; a total of 60 individuals were included.
Results: Clinical periodontal evaluation indices in the 6th week after treatment were found to be statistically significantly lower than the initial values of PI, GI, PPD, CAL in the periodontitis groups(p<0.05). Pre-treatment baseline NOX-1 values were singificantly higher in both periodontitis groups than healthy groups (p<0.05).  While the pre-menopausal and post-menopausal periodontitis groups before treatment had similar PI, PPD and CAL  values, the GI was found to be significantly higher in the post-menopausal periodontitis group(p <0.05).  While NOX-1 values in pre-treatment GCF samples were similar in pre-menopausal and post-menopausal periodontitis groups, NOX-1 values in the post-menopausal periodontitis group at the 6th week after treatment were found to be statistically higher than the pre-menopausal periodontitis group (p <0.05).
Conclusion: According to the results of our study, oxidative stress that increases with menopause may negatively affect the healing potential after periodontal treatment. Accordingly, antioxidant supplementation can be predicted with hormone replacement during this period.

Article Details

THE EFFECT OF MENOPAUSE ON NADPH OXIDASE LEVELS AFTER NON-SURGICAL PERIODONTAL TREATMENTS ON PATIENTS WITH PERIODONTITIS

Authors: Mahmut KAYAALTI | Vildan BOSTANCI | Halef DOGAN

Main Topics: Promotion of health

Journal: Cumhuriyet Dental Journal 2021 Vol.24 Issue 4, pp.415-426

Document Type: Article

Publication Date: 1/2022

Document Language: English

Document ID (Org No.): 2000734159

DOI: https://doi.org/10.7126/cumudj.1000295

Issues

Authors:

Mahmut KAYAALTI | Vildan BOSTANCI | Halef DOGAN

Main Topics:

Promotion of health

Journal:

Cumhuriyet Dental Journal 2021 Vol.24 Issue 4, pp.415-426

Document Type:

Article

Publication Date:

1/2022

Document Language:

English

Document ID (Org No.):

2000734159

DOI:

https://doi.org/10.7126/cumudj.1000295