Determinants of Anticoagulation Control in Patients Receiving Warfarin Therapy

Al-Shaer , Mohammad Hossam Eldeen; Mohammad , Mohammad Gouda; Ahmed , Islam Galal Sayed; Ibrahim , Ahmed Mohammed Badawy

Article Details

Determinants of Anticoagulation Control in Patients Receiving Warfarin Therapy

Authors:

Al-Shaer , Mohammad Hossam Eldeen | Mohammad , Mohammad Gouda | Ahmed , Islam Galal Sayed | Ibrahim , Ahmed Mohammed Badawy

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2020 Vol.81 Issue 7, pp.2389-2394

Document Type:

Article

Publication Date:

10/2020

Document Language:

English

Document ID (Org No.):

233454

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

Keywords:

Abstract:

 Background: Warfarin, nowadays is considered one of the most prescribed anticoagulant medications. In England for example, there is at least 1% of the whole population being prescribed warfarin. Despite the emergence of new agents of anticoagulants like NOACS, warfarin still prevail in most prescriptions knowing that it can’t be substituted in certain indications. Objectives: To assess different factors associated with International Normalized Ratio (INR) control in patients who are on warfarin therapy for different indications. Methods: A retrospective cohort study conducted in National Heart Institute Outpatient Anticoagulation Clinic over six-month period. It included 250 patients on warfarin therapy for different indications. Results: After calculating Time in Therapeutic Range (TTR) of each patient the level of anticoagulation control was determined using the following cut off values: a) Good control: TTR>70%, b) Intermediate control: TTR 50 -70 %, c) Poor control: TTR <50%. Majority of patients in our study 62% had poor control with TTR less than 50%. Conclusion: Majority of patients have poor anticoagulation control by means of TTR. Male gender, higher education and employment status are associated with higher mean TTR and better anticoagulation control. Male gender and employment were significant predictors for good INR control.

Article Details

Determinants of Anticoagulation Control in Patients Receiving Warfarin Therapy

Authors:

Al-Shaer , Mohammad Hossam Eldeen | Mohammad , Mohammad Gouda | Ahmed , Islam Galal Sayed | Ibrahim , Ahmed Mohammed Badawy

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2020 Vol.81 Issue 7, pp.2389-2394

Document Type:

Article

Publication Date:

10/2020

Document Language:

English

Document ID (Org No.):

233454

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002

Descriptors:

CARDIOVASCULAR DISEASES

BLOOD COAGULATION

WARFARIN

DRUGS

PATIENTS

EGYPT

Anticoagulation

INR Control

Warfarin

Issues

Article Details

Authors: Al-Shaer , Mohammad Hossam Eldeen | Mohammad , Mohammad Gouda | Ahmed , Islam Galal Sayed | Ibrahim , Ahmed Mohammed Badawy

Publisher: Pan Arab League of Continuous Medical Education

Main Topics: Medicine

Journal: The Egyptian Journal of Hospital Medicine 2020 Vol.81 Issue 7, pp.2389-2394

Document Type: Article

Publication Date: 10/2020

Document Language: English

Document ID (Org No.): 233454

Frequency: Quarterly

eISSN: 20907125

pISSN: 16872002

Descriptors:

Issues

Authors:

Al-Shaer , Mohammad Hossam Eldeen | Mohammad , Mohammad Gouda | Ahmed , Islam Galal Sayed | Ibrahim , Ahmed Mohammed Badawy

Publisher:

Pan Arab League of Continuous Medical Education

Main Topics:

Medicine

Journal:

The Egyptian Journal of Hospital Medicine 2020 Vol.81 Issue 7, pp.2389-2394

Document Type:

Article

Publication Date:

10/2020

Document Language:

English

Document ID (Org No.):

233454

Frequency:

Quarterly

eISSN:

20907125

pISSN:

16872002