An outcome analysis of 44 necrotizing fasciitis patients in a single center

Ayça Ergan Şahin; Emre Günenç

Article Details

An outcome analysis of 44 necrotizing fasciitis patients in a single center

Authors:

Ayça Ergan Şahin | Emre Günenç

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.38 Issue 2, pp.129-134

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001340974

pISSN:

1019-1941

Keywords:

Abstract:

 Objective: Necrotizing fasciitis NF is a life-threatening soft tissue infection with high mortality, requiring prompt diagnosis and surgical intervention. We have investigated the outcomes of NF patients in our center. Patients and Methods: This retrospective study analyzed 44 patients diagnosed with NF. The study aimed to explore the microbial etiology, predisposing factors, management strategies, The Laboratory Risk Indicator for Necrotizing Fasciitis LRINEC scores and their relationship to mortality. Radiological studies, including CT, MRI, and ultrasound, were used to confirm the diagnosis, followed by surgical debridement and appropriate antibiotic therapy. Results: The most common pathogen was Escherichia coli 26.9, with diabetes mellitus DM being the most frequent comorbidity 75. The mean age of patients was 54.6 years, and the overall mortality rate was 27.3. Elevated HbA1c levels and delayed surgical intervention were associated with higher mortality. However, neither LRINEC score nor the location of the infection had a significant impact on outcomes. Early debridement and control of infection were crucial for survival, particularly in patients with DM and high HbA1c. Conclusion: Our findings support the importance of early intervention and management in reducing mortality from NF. The study highlights the need for timely surgical debridement and careful management of comorbid conditions, particularly diabetes, in improving patient outcomes.

 Objective: Necrotizing fasciitis NF is a life-threatening soft tissue infection with high mortality, requiring prompt diagnosis and surgical intervention. We have investigated the outcomes of NF patients in our center. Patients and Methods: This retrospective study analyzed 44 patients diagnosed with NF. The study aimed to explore the microbial etiology, predisposing factors, management strategies, The Laboratory Risk Indicator for Necrotizing Fasciitis LRINEC scores and their relationship to mortality. Radiological studies, including CT, MRI, and ultrasound, were used to confirm the diagnosis, followed by surgical debridement and appropriate antibiotic therapy. Results: The most common pathogen was Escherichia coli 26.9, with diabetes mellitus DM being the most frequent comorbidity 75. The mean age of patients was 54.6 years, and the overall mortality rate was 27.3. Elevated HbA1c levels and delayed surgical intervention were associated with higher mortality. However, neither LRINEC score nor the location of the infection had a significant impact on outcomes. Early debridement and control of infection were crucial for survival, particularly in patients with DM and high HbA1c. Conclusion: Our findings support the importance of early intervention and management in reducing mortality from NF. The study highlights the need for timely surgical debridement and careful management of comorbid conditions, particularly diabetes, in improving patient outcomes.

 Objective: Necrotizing fasciitis NF is a life-threatening soft tissue infection with high mortality, requiring prompt diagnosis and surgical intervention. We have investigated the outcomes of NF patients in our center. Patients and Methods: This retrospective study analyzed 44 patients diagnosed with NF. The study aimed to explore the microbial etiology, predisposing factors, management strategies, The Laboratory Risk Indicator for Necrotizing Fasciitis LRINEC scores and their relationship to mortality. Radiological studies, including CT, MRI, and ultrasound, were used to confirm the diagnosis, followed by surgical debridement and appropriate antibiotic therapy. Results: The most common pathogen was Escherichia coli 26.9, with diabetes mellitus DM being the most frequent comorbidity 75. The mean age of patients was 54.6 years, and the overall mortality rate was 27.3. Elevated HbA1c levels and delayed surgical intervention were associated with higher mortality. However, neither LRINEC score nor the location of the infection had a significant impact on outcomes. Early debridement and control of infection were crucial for survival, particularly in patients with DM and high HbA1c. Conclusion: Our findings support the importance of early intervention and management in reducing mortality from NF. The study highlights the need for timely surgical debridement and careful management of comorbid conditions, particularly diabetes, in improving patient outcomes.

 Objective: Necrotizing fasciitis NF is a life-threatening soft tissue infection with high mortality, requiring prompt diagnosis and surgical intervention. We have investigated the outcomes of NF patients in our center. Patients and Methods: This retrospective study analyzed 44 patients diagnosed with NF. The study aimed to explore the microbial etiology, predisposing factors, management strategies, The Laboratory Risk Indicator for Necrotizing Fasciitis LRINEC scores and their relationship to mortality. Radiological studies, including CT, MRI, and ultrasound, were used to confirm the diagnosis, followed by surgical debridement and appropriate antibiotic therapy. Results: The most common pathogen was Escherichia coli 26.9, with diabetes mellitus DM being the most frequent comorbidity 75. The mean age of patients was 54.6 years, and the overall mortality rate was 27.3. Elevated HbA1c levels and delayed surgical intervention were associated with higher mortality. However, neither LRINEC score nor the location of the infection had a significant impact on outcomes. Early debridement and control of infection were crucial for survival, particularly in patients with DM and high HbA1c. Conclusion: Our findings support the importance of early intervention and management in reducing mortality from NF. The study highlights the need for timely surgical debridement and careful management of comorbid conditions, particularly diabetes, in improving patient outcomes.

Article Details

An outcome analysis of 44 necrotizing fasciitis patients in a single center

Authors:

Ayça Ergan Şahin | Emre Günenç

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.38 Issue 2, pp.129-134

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001340974

pISSN:

1019-1941

Necrotizing fasciitis

LRINEC

Surgical debridement

Fournier’s gangrene

Issues

Article Details

An outcome analysis of 44 necrotizing fasciitis patients in a single center

Authors: Ayça Ergan Şahin | Emre Günenç

Publisher: Marmara University

Main Topics: Surgery (Other)

Journal: Marmara Medical Journal Vol.38 Issue 2, pp.129-134

Document Type: Article

Publication Date: 5/2025

Document Language: English

Document ID (Org No.): 2001340974

pISSN: 1019-1941

Necrotizing fasciitis

LRINEC

Surgical debridement

Fournier’s gangrene

Issues

Authors:

Ayça Ergan Şahin | Emre Günenç

Publisher:

Marmara University

Main Topics:

Surgery (Other)

Journal:

Marmara Medical Journal Vol.38 Issue 2, pp.129-134

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001340974

pISSN:

1019-1941