The Effect of Hepatosteatosis on the Course of Chest CT Severity Scores in COVID-19 Patients

Ahmet Turan Kaya; Burcu Akman; Veysel Kaya; Şirin Çetin

Article Details

The Effect of Hepatosteatosis on the Course of Chest CT Severity Scores in COVID-19 Patients

Authors:

Ahmet Turan Kaya | Burcu Akman | Veysel Kaya | Şirin Çetin

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 5, pp.491-496

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001301333

pISSN:

2602-3741

Keywords:

Abstract:

 BackgroundAims: In the literature, the temporal variation of CT severity score CT-SS values on consecutive CTs, which is an indicator of pneumonia severity, according to the presence of hepatosteatosis was not evaluated. We aimed to investigate the effect of hepatosteatosis on the temporal change of CT-SS in COVID-19 patients. Material and Methods: Our retrospective study included 472 RT-PCR positive COVID-19 patients   18 years old admitted to our hospital between December 2021 and January 2022. Chest CT severity scores ranging from 0 to 5 were assigned to each lobe of the lung and total CT-SS was obtained. For quantitative analysis, if the hepaticsplenic attenuation ratio was 1, hepatosteatosis was defined. Wilcoxon test was used to evaluate the temporal changes of CT-SS values relative to the presence of hepatosteatosis. p0.05 was considered statistically significant. Results: Of the total 472 patients, 255472 54 were hepatosteatosis-positive. The frequency of hepatosteatosis was significantly higher in male patients, 167255 65.5 p0.001. The mean age was 64.0414.35 years. There was no significant difference between ICU admission and hepatosteatosis groups p0.269. There was no significant difference between mortality and the presence of hepatosteatosis p0.429. There was a significant increase between the 1st and the 2nd CT-SS in patients with hepatosteatosis p0.001. The increase in the second CT-SS was higher in patients with hepatosteatosis than in patients without hepatosteatosis. Conclusion: Hepatosteatosis may be an indicator of poor prognosis in the temporal change of pneumonia severity in COVID-19 patients.

 BackgroundAims: In the literature, the temporal variation of CT severity score CT-SS values on consecutive CTs, which is an indicator of pneumonia severity, according to the presence of hepatosteatosis was not evaluated. We aimed to investigate the effect of hepatosteatosis on the temporal change of CT-SS in COVID-19 patients. Material and Methods: Our retrospective study included 472 RT-PCR positive COVID-19 patients   18 years old admitted to our hospital between December 2021 and January 2022. Chest CT severity scores ranging from 0 to 5 were assigned to each lobe of the lung and total CT-SS was obtained. For quantitative analysis, if the hepaticsplenic attenuation ratio was 1, hepatosteatosis was defined. Wilcoxon test was used to evaluate the temporal changes of CT-SS values relative to the presence of hepatosteatosis. p0.05 was considered statistically significant. Results: Of the total 472 patients, 255472 54 were hepatosteatosis-positive. The frequency of hepatosteatosis was significantly higher in male patients, 167255 65.5 p0.001. The mean age was 64.0414.35 years. There was no significant difference between ICU admission and hepatosteatosis groups p0.269. There was no significant difference between mortality and the presence of hepatosteatosis p0.429. There was a significant increase between the 1st and the 2nd CT-SS in patients with hepatosteatosis p0.001. The increase in the second CT-SS was higher in patients with hepatosteatosis than in patients without hepatosteatosis. Conclusion: Hepatosteatosis may be an indicator of poor prognosis in the temporal change of pneumonia severity in COVID-19 patients.

 BackgroundAims: In the literature, the temporal variation of CT severity score CT-SS values on consecutive CTs, which is an indicator of pneumonia severity, according to the presence of hepatosteatosis was not evaluated. We aimed to investigate the effect of hepatosteatosis on the temporal change of CT-SS in COVID-19 patients. Material and Methods: Our retrospective study included 472 RT-PCR positive COVID-19 patients   18 years old admitted to our hospital between December 2021 and January 2022. Chest CT severity scores ranging from 0 to 5 were assigned to each lobe of the lung and total CT-SS was obtained. For quantitative analysis, if the hepaticsplenic attenuation ratio was 1, hepatosteatosis was defined. Wilcoxon test was used to evaluate the temporal changes of CT-SS values relative to the presence of hepatosteatosis. p0.05 was considered statistically significant. Results: Of the total 472 patients, 255472 54 were hepatosteatosis-positive. The frequency of hepatosteatosis was significantly higher in male patients, 167255 65.5 p0.001. The mean age was 64.0414.35 years. There was no significant difference between ICU admission and hepatosteatosis groups p0.269. There was no significant difference between mortality and the presence of hepatosteatosis p0.429. There was a significant increase between the 1st and the 2nd CT-SS in patients with hepatosteatosis p0.001. The increase in the second CT-SS was higher in patients with hepatosteatosis than in patients without hepatosteatosis. Conclusion: Hepatosteatosis may be an indicator of poor prognosis in the temporal change of pneumonia severity in COVID-19 patients.

 Amaç: Literatürde pnömoni şiddetinin bir göstergesi olan BT şiddet skoru BT-ŞS değerlerinin, ardışık BT lerde hepatosteatoz varlığına göre zamansal değişimi değerlendirilmemiştir. COVID-19 hastalarında, hepatosteatozun BT-ŞS nin geçici değişimi üzerindeki etkisini araştırmayı amaçladık. Materyal ve Metotlar: Retrospektif çalışmamıza Aralık 2021 ile Ocak 2022 tarihleri arasında hastanemize başvuran 472 RT-PCR pozitif COVID-19 hastası   18 yaş dâhil edildi. Akciğerin her lobuna 0 ile 5 arasında değişen toraks BT şiddet skorları atandı ve toplam BT-ŞS elde edildi. Kantitatif analiz için hepatikdalak atenüasyon oranı 1 ise, hepatosteatoz tanımlandı. BT-ŞS değerlerinin hepatosteatoz varlığına göre zamansal değişimlerini değerlendirmek için Wilcoxon testi kullanıldı. p0,05 istatistiksel olarak anlamlı kabul edildi. Bulgular: Toplam 472 hastanın 255472si 54 hepatosteatoz pozitifti. Hepatosteatoz sıklığı, erkek hastalarda anlamlı olarak yüksekti, 167255 65,5 p0,001. Ortalama yaş 64.0414.35 idi. Yoğun bakıma yatış ve hepatosteatoz grupları arasında anlamlı fark yoktu p0,269. Mortalite ile hepatosteatoz varlığı arasında anlamlı fark yoktu p0,429. Hepatosteatozlu hastalarda 1. ve 2. BT-ŞS arasında anlamlı artış vardı p0.001. İkinci CT-SSdeki artış hepatosteatozlu hastalarda hepatosteatozsuz hastalara göre daha yüksekti. Sonuç: Hepatosteatoz, COVID-19 hastalarında pnömoni şiddetinin geçici değişiminde kötü prognozun bir göstergesi olabilir.

Article Details

The Effect of Hepatosteatosis on the Course of Chest CT Severity Scores in COVID-19 Patients

Authors:

Ahmet Turan Kaya | Burcu Akman | Veysel Kaya | Şirin Çetin

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 5, pp.491-496

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001301333

pISSN:

2602-3741

COVID-19

Computed tomography severity score

hepatosteatosis

hepatic-to-splenic attenuation ratioCOVID-19

Bilgisayarlı Tomografi şiddet skoru

hepatosteatoz

hepatik-dalak atenüasyon oranı

Issues

Article Details

Authors: Ahmet Turan Kaya | Burcu Akman | Veysel Kaya | Şirin Çetin

Publisher: Selcuk University

Main Topics: Klinik Tıp Bilimleri

Journal: Genel Tıp Dergisi Vol.33 Issue 5, pp.491-496

Document Type: Article

Publication Date: 10/2023

Document Language: English

Document ID (Org No.): 2001301333

pISSN: 2602-3741

Issues

Authors:

Ahmet Turan Kaya | Burcu Akman | Veysel Kaya | Şirin Çetin

Publisher:

Selcuk University

Main Topics:

Klinik Tıp Bilimleri

Journal:

Genel Tıp Dergisi Vol.33 Issue 5, pp.491-496

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001301333

pISSN:

2602-3741