Characteristics of pediatric patients with chronic cough: data from a pediatric immunology and allergy outpatient clinic

Hilal Ünsal

Article Details

Characteristics of pediatric patients with chronic cough: data from a pediatric immunology and allergy outpatient clinic

Authors:

Hilal Ünsal

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Çocuk İmmünolojisi ve Alerji Hastalıkları | Alerji

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 1, pp.75-79

Document Type:

Article

Publication Date:

12/2025

Document Language:

English

Document ID (Org No.):

2001338922

pISSN:

2636-8579

Keywords:

Abstract:

 Aims: Chronic cough is a common complaint in childhood. A differential diagnosis is very important in children with a chronic cough. We aimed to investigate the etiology and underlying risk factors of chronic cough in children. Methods: Patients aged 1-18 years who were referred to Sincan Training and Research Hospital Pediatric Immunology and Allergy Outpatient Clinic were included. Demographic, clinical and laboratory features of patients were recorded. Results: The study included 403 children with a median age of 8 years IQR 6-12 53 males. 30 of patients had allergic rhinitis AR, 4.7 of patients had atopic dermatitis AD, and 2 patients had food allergy FA history. 7819.3 patients also complained of dyspnea and 9 2.2 patients had a diagnosis of cardiovascular disease. 245 60.8 asthma-wheezy infant, 107 26.6 post-infectious cough, 36 9 postnasal drip syndrome, 9 2.2 gastroesophageal reflux and 6 1.5 psychogenic cough were detected in the whole group. The number of patients with accompanying dyspnea 76 28.5 and familial history of atopy 113 42.3 were higher in the asthma-wheezy infant group than others group p0.001 vs. p0.001. Skin prick tests were performed in 273 patients and the presence of aeroallergen sensitivity was shown in 122 30.2 patients. Immunoglobulin deficiency was detected in 43 10.7 patients. Serum IgG, IgA, and IgM levels were low in 26 6.5, 18 4.4, and 12 3 patients, respectively. Conclusion: We found the most common reasons are asthma and post-infectious cough in patients. Chronic cough can be the first symptom of primary immunodeficiency diseases and systemic diseases. A detailed history is necessary to avoid unnecessary procedures, treatments and to avoid delay in diagnosis.

 Aims: Chronic cough is a common complaint in childhood. A differential diagnosis is very important in children with a chronic cough. We aimed to investigate the etiology and underlying risk factors of chronic cough in children. Methods: Patients aged 1-18 years who were referred to Sincan Training and Research Hospital Pediatric Immunology and Allergy Outpatient Clinic were included. Demographic, clinical and laboratory features of patients were recorded. Results: The study included 403 children with a median age of 8 years IQR 6-12 53 males. 30 of patients had allergic rhinitis AR, 4.7 of patients had atopic dermatitis AD, and 2 patients had food allergy FA history. 7819.3 patients also complained of dyspnea and 9 2.2 patients had a diagnosis of cardiovascular disease. 245 60.8 asthma-wheezy infant, 107 26.6 post-infectious cough, 36 9 postnasal drip syndrome, 9 2.2 gastroesophageal reflux and 6 1.5 psychogenic cough were detected in the whole group. The number of patients with accompanying dyspnea 76 28.5 and familial history of atopy 113 42.3 were higher in the asthma-wheezy infant group than others group p0.001 vs. p0.001. Skin prick tests were performed in 273 patients and the presence of aeroallergen sensitivity was shown in 122 30.2 patients. Immunoglobulin deficiency was detected in 43 10.7 patients. Serum IgG, IgA, and IgM levels were low in 26 6.5, 18 4.4, and 12 3 patients, respectively. Conclusion: We found the most common reasons are asthma and post-infectious cough in patients. Chronic cough can be the first symptom of primary immunodeficiency diseases and systemic diseases. A detailed history is necessary to avoid unnecessary procedures, treatments and to avoid delay in diagnosis.

 Aims: Chronic cough is a common complaint in childhood. A differential diagnosis is very important in children with a chronic cough. We aimed to investigate the etiology and underlying risk factors of chronic cough in children. Methods: Patients aged 1-18 years who were referred to Sincan Training and Research Hospital Pediatric Immunology and Allergy Outpatient Clinic were included. Demographic, clinical and laboratory features of patients were recorded. Results: The study included 403 children with a median age of 8 years IQR 6-12 53 males. 30 of patients had allergic rhinitis AR, 4.7 of patients had atopic dermatitis AD, and 2 patients had food allergy FA history. 7819.3 patients also complained of dyspnea and 9 2.2 patients had a diagnosis of cardiovascular disease. 245 60.8 asthma-wheezy infant, 107 26.6 post-infectious cough, 36 9 postnasal drip syndrome, 9 2.2 gastroesophageal reflux and 6 1.5 psychogenic cough were detected in the whole group. The number of patients with accompanying dyspnea 76 28.5 and familial history of atopy 113 42.3 were higher in the asthma-wheezy infant group than others group p0.001 vs. p0.001. Skin prick tests were performed in 273 patients and the presence of aeroallergen sensitivity was shown in 122 30.2 patients. Immunoglobulin deficiency was detected in 43 10.7 patients. Serum IgG, IgA, and IgM levels were low in 26 6.5, 18 4.4, and 12 3 patients, respectively. Conclusion: We found the most common reasons are asthma and post-infectious cough in patients. Chronic cough can be the first symptom of primary immunodeficiency diseases and systemic diseases. A detailed history is necessary to avoid unnecessary procedures, treatments and to avoid delay in diagnosis.

 Amaç: Kronik öksürük çocukluk çağında sık görülen bir şikayettir. Kronik öksürüğü olan çocuklarda ayırıcı tanı çok önemlidir. Çocuklarda kronik öksürüğün etiyolojisini ve altta yatan risk faktörlerini araştırmayı amaçladık. Yöntemler: Sincan Eğitim ve Araştırma Hastanesi Çocuk İmmünoloji ve Alerji Polikliniğine sevk edilen 1-18 yaş arası hastalar çalışmaya dahil edildi. Hastaların demografik, klinik ve laboratuvar özellikleri kaydedildi. Sonuçlar: Çalışmaya ortanca yaşı 8 yıl IQR 6-12 olan 403 çocuk dahil edildi 53 erkek. Hastaların 30unda alerjik rinit AR, 4,7sinde atopik dermatit AD ve 2sinde gıda alerjisi FA öyküsü vardı. 78 19,3 hastada ayrıca dispne şikayeti vardı ve 9 2,2 hastada kardiyovasküler hastalık tanısı vardı. Tüm grupta 245 60,8 astım-hırıltılı bebek, 107 26,6 postenfeksiyöz öksürük, 36 9 postnazal damla sendromu, 9 2,2 gastroözofageal reflü ve 6 1,5 psikojenik öksürük tespit edildi. Eşlik eden dispnesi olan hasta sayısı 76 28,5 ve ailede atopi öyküsü olan hasta sayısı 113 42,3 astım-hırıltılı bebek grubunda diğer gruplardan daha fazlaydı p0,001 vs. p0,001. 273 hastaya deri prick testi yapıldı ve 122 30,2 hastada aeroalerjen duyarlılığı varlığı gösterildi. 43 10,7 hastada immünglobulin eksikliği tespit edildi. Serum IgG, IgA ve IgM düzeyleri sırasıyla 26 6,5, 18 4,4 ve 12 3 hastada düşüktü. Sonuç: Hastalarda en sık görülen nedenlerin astım ve enfeksiyon sonrası öksürük olduğunu bulduk. Kronik öksürük, primer immün yetmezlik hastalıkları ve sistemik hastalıkların ilk belirtisi olabilir. Gereksiz prosedürlerden, tedavilerden kaçınmak ve tanıda gecikmeyi önlemek için ayrıntılı bir öykü gereklidir.

Article Details

Characteristics of pediatric patients with chronic cough: data from a pediatric immunology and allergy outpatient clinic

Authors:

Hilal Ünsal

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Çocuk İmmünolojisi ve Alerji Hastalıkları | Alerji

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 1, pp.75-79

Document Type:

Article

Publication Date:

12/2025

Document Language:

English

Document ID (Org No.):

2001338922

pISSN:

2636-8579

Asthma

chronic cough

children

immunoglobulinAstım

kronik öksürük

çocuklar

immünoglobulin

Issues

Article Details

Authors: Hilal Ünsal

Publisher: MediHealth Academy Yayıncılık

Main Topics: Çocuk İmmünolojisi ve Alerji Hastalıkları | Alerji

Journal: Journal of Health Sciences and Medicine Vol.8 Issue 1, pp.75-79

Document Type: Article

Publication Date: 12/2025

Document Language: English

Document ID (Org No.): 2001338922

pISSN: 2636-8579

Issues

Authors:

Hilal Ünsal

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Çocuk İmmünolojisi ve Alerji Hastalıkları | Alerji

Journal:

Journal of Health Sciences and Medicine Vol.8 Issue 1, pp.75-79

Document Type:

Article

Publication Date:

12/2025

Document Language:

English

Document ID (Org No.):

2001338922

pISSN:

2636-8579