Quasielastic light scattering studies of polypeptides: evidence for chain extension in solution

Bahattin M. BAYSAL; Çiğdem KARADAĞ

Article Details

Quasielastic light scattering studies of polypeptides: evidence for chain extension in solution

Authors:

Bahattin M. BAYSAL | Çiğdem KARADAĞ

Publisher:

TUBITAK

Journal:

Turkish Journal of Chemistry 2013 Vol.37 Issue 4, pp.480-491

Document Type:

Article

Publication Date:

3/2013

Document Language:

Turkish

Document ID (Org No.):

2000727362

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527

Abstract:

 

Dynamic light scattering and viscosimetric methods were used to study   polypeptides including polyleucine, poly (g-benzyl-L-glutamate),   poly (a-L-glutamic acid), and polyproline II. Chain extension   showing rod-like and flexible conformations occurred in poly(g  -benzyl-L-glutamate) and polyproline II solutions as these solutions were   diluted in glacial acetic acid or in a mixed solvent of acetic acid and   dichloromethane. The elongation of chains in poly(g  -benzyl-L-glutamate) and polyproline II solutions was studied by dynamic   light scattering and viscosimetric methods. This nonenzymatic growth of   peptide chains provides data on primordial synthesis of protein molecules in   the absence of cell machinery and for this reason these reactions may yield   valuable data for further studies.

 

Dynamic light scattering and viscosimetric methods were used to study   polypeptides including polyleucine, poly (g-benzyl-L-glutamate),   poly (a-L-glutamic acid), and polyproline II. Chain extension   showing rod-like and flexible conformations occurred in poly(g  -benzyl-L-glutamate) and polyproline II solutions as these solutions were   diluted in glacial acetic acid or in a mixed solvent of acetic acid and   dichloromethane. The elongation of chains in poly(g  -benzyl-L-glutamate) and polyproline II solutions was studied by dynamic   light scattering and viscosimetric methods. This nonenzymatic growth of   peptide chains provides data on primordial synthesis of protein molecules in   the absence of cell machinery and for this reason these reactions may yield   valuable data for further studies.

Article Details

Quasielastic light scattering studies of polypeptides: evidence for chain extension in solution

Authors: Bahattin M. BAYSAL | Çiğdem KARADAĞ

Publisher: TUBITAK

Journal: Turkish Journal of Chemistry 2013 Vol.37 Issue 4, pp.480-491

Document Type: Article

Publication Date: 3/2013

Document Language: Turkish

Document ID (Org No.): 2000727362

Frequency: Bimonthly

eISSN: 1303-6130

pISSN: 1300-0527

Issues

Authors:

Bahattin M. BAYSAL | Çiğdem KARADAĞ

Publisher:

TUBITAK

Journal:

Turkish Journal of Chemistry 2013 Vol.37 Issue 4, pp.480-491

Document Type:

Article

Publication Date:

3/2013

Document Language:

Turkish

Document ID (Org No.):

2000727362

Frequency:

Bimonthly

eISSN:

1303-6130

pISSN:

1300-0527