Risk factors for coronary artery disease in young patients with stable angina pectoris

Mustafa DURAN; Deniz ELÇİK; Sani Namik MURAT; Fatih ÖKSÜZ; İbrahim Etem ÇELİK

Article Details

Risk factors for coronary artery disease in young patients with stable angina pectoris

Authors:

Mustafa DURAN | Deniz ELÇİK | Sani Namik MURAT | Fatih ÖKSÜZ | İbrahim Etem ÇELİK

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.993-998

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

2000749952

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144

Abstract:

 

Background/aim: We aimed to investigate the relationship between risk factors and the presence of coronary artery disease (CAD) in a young population with stable angina pectoris (SAP).Materials  and  methods:  A  total  of571  individuals  younger  than  60  years  old,  admitted  to  the  outpatient  clinic  with  chest  pain  and  referred for coronary angiography between January 2015 and December 2017, were included in the study. All clinical and biochemical parameters were documented in the hospital records. Coronary angiography of patients was monitored from records. The individuals were divided into two groups. The patient group consisted of 363 individuals with at least one-vessel stenosis of ≥70%, and the control group consisted of 208 individuals with normal coronary angiography. We compared the traditional and nontraditional risk factors of these two groups in terms of the presence of CAD.Results: Prevalence  of  male  sex  and  smoking  were  higher  in  the  patient  group,  and  the  prevalence  of  hypertension  and  diabetes  were  similar  in  the  two  groups.  In  the  patient  group,  mean  age,  blood  cholesterols,  serum  gamma-glutamyltransferase,  hemoglobin,  and  white  blood  cell  and  lymphocyte  levels  were  higher,  while  estimated  glomerular  filtration  rate  (eGFR),  high-density  lipoprotein  cholesterol (HDL-C), platelets, and neutrophil/lymphocyte and platelet/lymphocyte ratios were lower. Low eGFR and HDL-C levels, older age, male sex, smoking, and high levels of low-density lipoprotein cholesterol and lymphocytes were independent risk factors for the presence of CAD in young patients.Conclusion: Contrary  to  studies  performed  in  the  elderly,  traditional  and  nontraditional  risk  factors  could  not  exactly  predict  the  presence of CAD in a young population with SAP.

Article Details

Risk factors for coronary artery disease in young patients with stable angina pectoris

Authors: Mustafa DURAN | Deniz ELÇİK | Sani Namik MURAT | Fatih ÖKSÜZ | İbrahim Etem ÇELİK

Publisher: TUBITAK

Journal: Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.993-998

Document Type: Article

Publication Date: 7/2019

Document Language: English

Document ID (Org No.): 2000749952

Frequency: Bimonthly

eISSN: 1303-6165

pISSN: 1300-0144

Issues

Authors:

Mustafa DURAN | Deniz ELÇİK | Sani Namik MURAT | Fatih ÖKSÜZ | İbrahim Etem ÇELİK

Publisher:

TUBITAK

Journal:

Turkish Journal of Medical Sciences 2019 Vol.49 Issue 4, pp.993-998

Document Type:

Article

Publication Date:

7/2019

Document Language:

English

Document ID (Org No.):

2000749952

Frequency:

Bimonthly

eISSN:

1303-6165

pISSN:

1300-0144