Breast Cancer during Pregnancy = سرطان الثدي خلال فترة الحمل

Kamal Eldein H. Mohamed; Maawia Elsadig

doi:10.12816/0030337

Article Details

Breast Cancer during Pregnancy = سرطان الثدي خلال فترة الحمل

Authors:

Kamal Eldein H. Mohamed | Maawia Elsadig

Publisher:

Sudan Medical Association

Main Topics:

Medicine

Journal:

Sudan Medical Journal 2016 Vol.52 Issue 2, pp.49-53

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

92835

Frequency:

Tri-Annual

pISSN:

04914481

DOI:

10.12816/0030337

Descriptors:

Keywords:

Abstract:

 Breast cancer is the most common cancer during pregnancy, with an average of one case per 3000 pregnancies. It has been estimated that up to 3% of breast cancer occur during pregnancy, almost 80% of all breast lumps during pregnancy are benign. Surgical treatment can be done safely during all trimesters of pregnancy. Chemotherapy is contraindicated during the first trimester of pregnancy, due to its teratogenic effects, but can be given safely during the second and third trimesters. Delivery shouldn‟t be induced before the 37thweeks.
Diagnosis
The physiological changes which occur during pregnancy in the breast may delay diagnosis, as small lumps may be difficult to detect. The diagnosis, like in non-pregnant women, is based on the triad of clinical assessment, imaging (US and mammography with good shielding), and tissue biopsy (Trucut). Clinical examination of the breast during antenatal care should be a routine.
Mammography can be done during pregnancy, experts agree that craniocauadal and mediolateral views with adequate shielding to maintain fetal dose below the permissible radiation dose can be performed, but due to the increased density and vascularity of the breasts during pregnancy interpretation may be difficult. With proper shielding the estimated dose of radiation of 2 views is 200- 400 mCgy, and a sensitivity of 78 - 90% was reported. However, US is more accessible, very useful and has high sensitivity and
specificity and can differentiate between solid and cystic masses. Trucut biopsy offers a reliable diagnostic tool with a sensitivity around 90%, and an extra benefit of receptors assay unlike Fine Needle Aspiration which may be misleading during pregnancy. The predominant type of breast cancer during pregnancy is invasive ductal cancer as in non pregnant women

 يحدث سرطان الثدي عند النساء اثناء الحمل بمعدل حاله واحده في كل 300 حمل يمكن عمل انواع الجراحة المختلفة اثناء الحمل ويمكن اعطاء العلاج الكيميائي اثناء الثلث الثاني والاخير للحمل بدون ثأثير سلبي كثير على المولود ولا يعطي العلاج الكيميائي اثناء الثلث الاول للحمل لانه يضر الجنين كثيرا وممكن عمل الجراحة للثدي اثناء الحمل بسلام اما العلاج بالهرمون بعقار التاموكسيفين فيجب تجنبه لانه يسبب تشوهات خلقية للجنين عموما العلاج الكيميائي لسرطان الثدي اثناء الحمل ممكن وبدون مخاطر على الجنين ونتائجه جيده ويمكن ان يؤدي لتفادي اجراء عملية ازالة الثدي .

Article Details

Breast Cancer during Pregnancy = سرطان الثدي خلال فترة الحمل

Authors:

Kamal Eldein H. Mohamed | Maawia Elsadig

Publisher:

Sudan Medical Association

Main Topics:

Medicine

Journal:

Sudan Medical Journal 2016 Vol.52 Issue 2, pp.49-53

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

92835

Frequency:

Tri-Annual

pISSN:

04914481

DOI:

10.12816/0030337

Descriptors:

BREAST CANCER

CANCER

CHEMOTHERAPY

GESTATION PERIOD

PREGNANT WOMEN

Breast Cancer

Pregnancy

Chemotherapy

Issues

Article Details

Authors: Kamal Eldein H. Mohamed | Maawia Elsadig

Publisher: Sudan Medical Association

Main Topics: Medicine

Journal: Sudan Medical Journal 2016 Vol.52 Issue 2, pp.49-53

Document Type: Article

Publication Date: 8/2016

Document Language: English

Document ID (Org No.): 92835

Frequency: Tri-Annual

pISSN: 04914481

DOI: 10.12816/0030337

Descriptors:

Issues

Authors:

Kamal Eldein H. Mohamed | Maawia Elsadig

Publisher:

Sudan Medical Association

Main Topics:

Medicine

Journal:

Sudan Medical Journal 2016 Vol.52 Issue 2, pp.49-53

Document Type:

Article

Publication Date:

8/2016

Document Language:

English

Document ID (Org No.):

92835

Frequency:

Tri-Annual

pISSN:

04914481

DOI:

10.12816/0030337