Investigation of Biochemical Properties of Acetone O-(4-chlorophenylsulfonyl)oxime and Acetone O-(2-naphthylsulfonyl)oxime

Pınar Yalçın; Abdurrahman Dündar; Veysi Okumuş

Article Details

Investigation of Biochemical Properties of Acetone O-(4-chlorophenylsulfonyl)oxime and Acetone O-(2-naphthylsulfonyl)oxime

Authors:

Pınar Yalçın | Abdurrahman Dündar | Veysi Okumuş

Publisher:

Mus Alparslan University

Main Topics:

Biyomedikal Bilimler ve Teknolojiler

Journal:

Hendese Teknik Bilimler ve Mühendislik Dergisi Vol.1 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001315949

pISSN:

3023-7777

Keywords:

Abstract:

 The purpose of this study is to survey if acetone O-4 chlorophenylsulfonyl oxime and acetone O-2-naphtylsülphonyloxime compounds have antimicrobial and antioxidant properties or not. For this purpose, the antioxidant activity of the compounds was tested using the DPPH free radical method and the method of determining the antibacterial activity of newly synthesized compounds. As a result, compound 1a shows better antioxidant activity than compound 2a at all tested concentrations. The antibacterial activities of sulfonate derivatives on Staphylococcus aureus, Bacillus sps, Escherichia coli, and Klebsiella pneumoniae strains were investigated and it was determined that all compounds showed partial antibacterial activity for S. aureus, E. coli, and K. pneumoniae strains.

 The purpose of this study is to survey if acetone O-4 chlorophenylsulfonyl oxime and acetone O-2-naphtylsülphonyloxime compounds have antimicrobial and antioxidant properties or not. For this purpose, the antioxidant activity of the compounds was tested using the DPPH free radical method and the method of determining the antibacterial activity of newly synthesized compounds. As a result, compound 1a shows better antioxidant activity than compound 2a at all tested concentrations. The antibacterial activities of sulfonate derivatives on Staphylococcus aureus, Bacillus sps, Escherichia coli, and Klebsiella pneumoniae strains were investigated and it was determined that all compounds showed partial antibacterial activity for S. aureus, E. coli, and K. pneumoniae strains.

 The purpose of this study is to survey if acetone O-4 chlorophenylsulfonyl oxime and acetone O-2-naphtylsülphonyloxime compounds have antimicrobial and antioxidant properties or not. For this purpose, the antioxidant activity of the compounds was tested using the DPPH free radical method and the method of determining the antibacterial activity of newly synthesized compounds. As a result, compound 1a shows better antioxidant activity than compound 2a at all tested concentrations. The antibacterial activities of sulfonate derivatives on Staphylococcus aureus, Bacillus sps, Escherichia coli, and Klebsiella pneumoniae strains were investigated and it was determined that all compounds showed partial antibacterial activity for S. aureus, E. coli, and K. pneumoniae strains.

 Bu çalışmanın amacı, aseton O-4 klorofenilsülfonil oksim ve aseton O-2-naftilsülfoniloksim bileşiklerinin antimikrobiyal ve antioksidan özelliklere sahip olup olmadığını araştırmaktır. Bu amaçla bileşiklerin antioksidan aktiviteleri DPPH serbest radikal yöntemi ile antioksidan ve antibakteriyel aktivitelerinin belirlenmiştir. Sonuç olarak bileşik 1a, test edilen tüm konsantrasyonlarda bileşik 2adan daha iyi antioksidan aktivite gösterir. Sülfonat türevlerinin Staphylococcus aureus, Bacillus sps, Escherichia coli ve Klebsiella pneumoniae suşları üzerindeki antibakteriyel aktiviteleri araştırılmış ve tüm bileşiklerin S. aureus, E. coli ve K. pneumoniae suşlarına karşı kısmi antibakteriyel aktivite gösterdiği tespit edilmiştir.

Article Details

Investigation of Biochemical Properties of Acetone O-(4-chlorophenylsulfonyl)oxime and Acetone O-(2-naphthylsulfonyl)oxime

Authors:

Pınar Yalçın | Abdurrahman Dündar | Veysi Okumuş

Publisher:

Mus Alparslan University

Main Topics:

Biyomedikal Bilimler ve Teknolojiler

Journal:

Hendese Teknik Bilimler ve Mühendislik Dergisi Vol.1 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001315949

pISSN:

3023-7777

Acetone O-(4-chlorophenylsulfonyl)oxime

Acetone O-(2-naphtylsülphonyl)Oxime

Antimicrobial activity

Antioxidant activity

Docking

ADMETAseton

Aseton oksim

Antimikrobiyal aktivite

Antioksidan aktivite

Docking

ADMET

Issues

Article Details

Authors: Pınar Yalçın | Abdurrahman Dündar | Veysi Okumuş

Publisher: Mus Alparslan University

Main Topics: Biyomedikal Bilimler ve Teknolojiler

Journal: Hendese Teknik Bilimler ve Mühendislik Dergisi Vol.1 Issue 1, pp.7-11

Document Type: Article

Publication Date: 4/2024

Document Language: English

Document ID (Org No.): 2001315949

pISSN: 3023-7777

Issues

Authors:

Pınar Yalçın | Abdurrahman Dündar | Veysi Okumuş

Publisher:

Mus Alparslan University

Main Topics:

Biyomedikal Bilimler ve Teknolojiler

Journal:

Hendese Teknik Bilimler ve Mühendislik Dergisi Vol.1 Issue 1, pp.7-11

Document Type:

Article

Publication Date:

4/2024

Document Language:

English

Document ID (Org No.):

2001315949

pISSN:

3023-7777