High versus low dialysate sodium: a single-center small-scale prospective study

Sara İleri

Article Details

High versus low dialysate sodium: a single-center small-scale prospective study

Authors:

Sara İleri

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Nefroloji

Journal:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.196-200

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343187

pISSN:

2718-0115

Keywords:

Abstract:

 Aims: The matter of dialysate sodium concentration has become progressively substantial in the last 50 years, when dialysis modalities have advanced quickly. In many studies, it has been established that dialysate sodium value is correlated with blood pressure alternance, hypervolemia, interdialytic weight gain IDWG, and chronic inflammation. However, there is no clear knowledge about its direct effect on inflammation. In this study, we profited from high-sensitivity C-reactive protein hs-CRP, which is a helpful marker, to survey the inflammation correlation with dialysate sodium DNa. Methods: 109 non-diabetic hemodialysis patients were enrolled in the study. All patients participating in the study were new onset, less than 6 months dialysis patients and met KtV of 1.4 at minimum criteria. Results: They were divided into two groups: group 1, low dialysate sodium 137 mmolL and group 2, conventional dialysate sodium 140 mmolL and followed-up for two months. During the follow-up period, serum hs-CRP levels were measured and categorized as baseline, 1st month and second month level. Conclusion: As a result, no statistically remarkable disparity between the groups were determined in terms of serum hs-CRP levels at baseline, 1st month, and 2nd month of the study p0.05. We did not establish any significant differences that would make it worth ignoring some symptoms symptoms such as cramps and hypotension.

 Aims: The matter of dialysate sodium concentration has become progressively substantial in the last 50 years, when dialysis modalities have advanced quickly. In many studies, it has been established that dialysate sodium value is correlated with blood pressure alternance, hypervolemia, interdialytic weight gain IDWG, and chronic inflammation. However, there is no clear knowledge about its direct effect on inflammation. In this study, we profited from high-sensitivity C-reactive protein hs-CRP, which is a helpful marker, to survey the inflammation correlation with dialysate sodium DNa. Methods: 109 non-diabetic hemodialysis patients were enrolled in the study. All patients participating in the study were new onset, less than 6 months dialysis patients and met KtV of 1.4 at minimum criteria. Results: They were divided into two groups: group 1, low dialysate sodium 137 mmolL and group 2, conventional dialysate sodium 140 mmolL and followed-up for two months. During the follow-up period, serum hs-CRP levels were measured and categorized as baseline, 1st month and second month level. Conclusion: As a result, no statistically remarkable disparity between the groups were determined in terms of serum hs-CRP levels at baseline, 1st month, and 2nd month of the study p0.05. We did not establish any significant differences that would make it worth ignoring some symptoms symptoms such as cramps and hypotension.

 Aims: The matter of dialysate sodium concentration has become progressively substantial in the last 50 years, when dialysis modalities have advanced quickly. In many studies, it has been established that dialysate sodium value is correlated with blood pressure alternance, hypervolemia, interdialytic weight gain IDWG, and chronic inflammation. However, there is no clear knowledge about its direct effect on inflammation. In this study, we profited from high-sensitivity C-reactive protein hs-CRP, which is a helpful marker, to survey the inflammation correlation with dialysate sodium DNa. Methods: 109 non-diabetic hemodialysis patients were enrolled in the study. All patients participating in the study were new onset, less than 6 months dialysis patients and met KtV of 1.4 at minimum criteria. Results: They were divided into two groups: group 1, low dialysate sodium 137 mmolL and group 2, conventional dialysate sodium 140 mmolL and followed-up for two months. During the follow-up period, serum hs-CRP levels were measured and categorized as baseline, 1st month and second month level. Conclusion: As a result, no statistically remarkable disparity between the groups were determined in terms of serum hs-CRP levels at baseline, 1st month, and 2nd month of the study p0.05. We did not establish any significant differences that would make it worth ignoring some symptoms symptoms such as cramps and hypotension.

 Aims: The matter of dialysate sodium concentration has become progressively substantial in the last 50 years, when dialysis modalities have advanced quickly. In many studies, it has been established that dialysate sodium value is correlated with blood pressure alternance, hypervolemia, interdialytic weight gain IDWG, and chronic inflammation. However, there is no clear knowledge about its direct effect on inflammation. In this study, we profited from high-sensitivity C-reactive protein hs-CRP, which is a helpful marker, to survey the inflammation correlation with dialysate sodium DNa. Methods: 109 non-diabetic hemodialysis patients were enrolled in the study. All patients participating in the study were new onset, less than 6 months dialysis patients and met KtV of 1.4 at minimum criteria. Results: They were divided into two groups: group 1, low dialysate sodium 137 mmolL and group 2, conventional dialysate sodium 140 mmolL and followed-up for two months. During the follow-up period, serum hs-CRP levels were measured and categorized as baseline, 1st month and second month level. Conclusion: As a result, no statistically remarkable disparity between the groups were determined in terms of serum hs-CRP levels at baseline, 1st month, and 2nd month of the study p0.05. We did not establish any significant differences that would make it worth ignoring some symptoms symptoms such as cramps and hypotension.

Article Details

High versus low dialysate sodium: a single-center small-scale prospective study

Authors:

Sara İleri

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Nefroloji

Journal:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.196-200

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343187

pISSN:

2718-0115

Chronic kidney disease

hemodialysis

dialysate sodium

chronic inflammation

high-sensitivity CRP

Issues

Article Details

High versus low dialysate sodium: a single-center small-scale prospective study

Authors: Sara İleri

Publisher: MediHealth Academy Yayıncılık

Main Topics: Nefroloji

Journal: Anatolian Current Medical Journal Vol.7 Issue 2, pp.196-200

Document Type: Article

Publication Date: 3/2025

Document Language: English

Document ID (Org No.): 2001343187

pISSN: 2718-0115

Chronic kidney disease

hemodialysis

dialysate sodium

chronic inflammation

high-sensitivity CRP

Issues

Authors:

Sara İleri

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Nefroloji

Journal:

Anatolian Current Medical Journal Vol.7 Issue 2, pp.196-200

Document Type:

Article

Publication Date:

3/2025

Document Language:

English

Document ID (Org No.):

2001343187

pISSN:

2718-0115