Mucocutaneous Side Effects of Antineoplastic Drugs Used in Cancer Therapy in Erbil

Niyan Othman  Hama Faraj; Mohammed Yousif  Saeed

Article Details

Mucocutaneous Side Effects of Antineoplastic Drugs Used in Cancer Therapy in Erbil

Authors:

Niyan Othman Hama Faraj | Mohammed Yousif Saeed

Publisher:

Kurdistan Higher Council of Medical Specialties

Journal:

Advanced medical journal Vol.5 Issue 1, pp.1-6

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

2001930891

pISSN:

2958-8979

Abstract:

 Background and objectives: Mucocutaneous side effects of antineoplastic drugs can produce both local and systemic mucocutaneous adverse reactions that sometimes misinterpreted with other cancer related dermatological mani- festations such as infection, paraneoplastic diseases, and nutritional deficiency. The aim of the study was to identify the most common mucocutaneous side effects associated with antineoplastic drugs to be looked for and managed properly. Methods:A study was conducted on patients receiving anti-cancer therapy. Data were collected from 109 patients, of which 87 were females and 22 were males, with biopsy proven malignancies. Forty one patients were on single chemotherapy and 68 were on combined chemotherapy. Seventy seven patients were on conventional chemo- therapy, 29 on hormonal therapy and 13 on immune target therapy. Detailed history was obtained from the patients. Afterwards each patient subjected to full dermatological examination involving skin, mucosa, hair and nail. Results: Hair changes were the most common adverse effect noticed in (31.71%) of the patients with anagen effluvium being the most common (68 cases), followed by skin changes in (28.29%). Nail changes were observed in (20.49%) of the cases and the most common changes were melanonychia that was noticed in 22.The mucosal changes accounted for (19.51%) of the cases and 36 patients complained of apthus ulcer. Conclusions:This study showed that adverse effects of antineoplastic drugs can cause a great degree of morbidity to cancer patients on chemotherapy although most of the complications subsided with cessation of the therapy without causing permanent damage.

Article Details

Mucocutaneous Side Effects of Antineoplastic Drugs Used in Cancer Therapy in Erbil

Authors: Niyan Othman Hama Faraj | Mohammed Yousif Saeed

Publisher: Kurdistan Higher Council of Medical Specialties

Journal: Advanced medical journal Vol.5 Issue 1, pp.1-6

Document Type: Article

Publication Date: 1/2019

Document Language: English

Document ID (Org No.): 2001930891

pISSN: 2958-8979

Issues

Authors:

Niyan Othman Hama Faraj | Mohammed Yousif Saeed

Publisher:

Kurdistan Higher Council of Medical Specialties

Journal:

Advanced medical journal Vol.5 Issue 1, pp.1-6

Document Type:

Article

Publication Date:

1/2019

Document Language:

English

Document ID (Org No.):

2001930891

pISSN:

2958-8979