Comparison of disease severity and ultrasonographic abdominal subcutaneous fatty tissue thickness in hirsute women

Betül Taş; Gökhan Artar; Mehmet Öncü; Saadet Pilten; Murat Altuntaş

doi:https://doi.org/10.7197/223.vi.404897

Article Details

Comparison of disease severity and ultrasonographic abdominal subcutaneous fatty tissue thickness in hirsute women

Authors:

Betül Taş | Gökhan Artar | Mehmet Öncü | Saadet Pilten | Murat Altuntaş

Main Topics:

Promotion of health

Journal:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 3, pp.246-256

Document Type:

Article

Publication Date:

9/2018

Document Language:

English

Document ID (Org No.):

2000922706

DOI:

https://doi.org/10.7197/223.vi.404897

Abstract:

 


Introduction


Hirsutism is a
condition defining as acquired excess of hairs in the androgen-sensitive skin
regions of women. It may be idiopathic, or can be resulted from metabolic or
androgen-related disorders. 


Aim


In order to
determine of possible correlation between hirsutism scores and central obesity,
comparisons of abdominal subcutaneous fatty tissue thickness, metabolic
syndrome criteria and also hirsutism-related hormones, according to hirsutism
stages were aimed.


Materials
and Methods


A prospective
study was conducted on 144 women between the ages of 18-50, from October 2014
to March 2016. Beside hirsutism scores (determined by modified Ferriman-Gallway
evaluation system) and subcutaneous
abdominal fatty tissue thickness, metabolic syndrome criteria and
hirsutism-related hormones were detected. Fatty tissue thicknes were determined
by ultrasonographic measurements from 4 points around the umbilicus. Data was
compared to hirsutism stages, and evaluated with Number Cruncher Statistical
System 2007, as considered p < 0.05 was significant.


Results


Only moderate
and severe hirsutism groups were detected, and mean age was 24.47 ±7.52 years.
The most accompanying finding was polycystic ovary syndrome. Higher means for
fatty tissue thickness (p=0.0001 for each four region), weight, body mass
index, waist circumferences, systolic and diastolic blood pressures (each
p=0.0001), insulin (p=0.038), Homeostatic Model Assesment for Insulin
Resistance (p=0.033), triglyceride (p=0.003), free androgen index (p=0.004) and
total testosterone  (p=0.036), and lower
means for high density lipoprotein cholesterol (p=0.003) and sex hormone
binding globuline (p=0.008) were obtained in severe hirsutism group. Existence of  1, 2 and 3 metabolic syndrome criteria, and
diagnosis of metabolic syndrome were also more detected in higher-score group
(each p=0.0001). 


Conclusion 


Women with
higher hirsutism scores are more likely to develop thicker subcutaneous
abdominal fatty tissue and metabolic syndrome than those with moderate scores.
Subcutaneous abdominal fatty tissue thicknesss may a simple metabotrophic
indicator for preliminary assessment of severity of hirsutism in especially
overweight women. 


.

Article Details

Comparison of disease severity and ultrasonographic abdominal subcutaneous fatty tissue thickness in hirsute women

Authors: Betül Taş | Gökhan Artar | Mehmet Öncü | Saadet Pilten | Murat Altuntaş

Main Topics: Promotion of health

Journal: Cumhuriyet Medical Journal 2018 Vol.40 Issue 3, pp.246-256

Document Type: Article

Publication Date: 9/2018

Document Language: English

Document ID (Org No.): 2000922706

DOI: https://doi.org/10.7197/223.vi.404897

Issues

Authors:

Betül Taş | Gökhan Artar | Mehmet Öncü | Saadet Pilten | Murat Altuntaş

Main Topics:

Promotion of health

Journal:

Cumhuriyet Medical Journal 2018 Vol.40 Issue 3, pp.246-256

Document Type:

Article

Publication Date:

9/2018

Document Language:

English

Document ID (Org No.):

2000922706

DOI:

https://doi.org/10.7197/223.vi.404897