The relationship between advanced maternal age and adverse pregnancy outcomes

İsa Temur

Article Details

The relationship between advanced maternal age and adverse pregnancy outcomes

Authors:

İsa Temur

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Kadın Hastalıkları ve Doğum

Journal:

Anatolian Current Medical Journal Vol.7 Issue 3, pp.304-310

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001349431

pISSN:

2718-0115

Keywords:

Abstract:

 Aims: This study aimed to evaluate the impact of advanced maternal age on pregnancy and neonatal outcomes. Methods: In this retrospective study, singleton pregnancies delivered at a tertiary care center between January 2021 and December 2023 were assessed. Participants were divided into two groups based on maternal age at delivery: 1835 years and 35 years. Maternal and perinatal outcomes were compared between the groups using Chi-square tests. Results: The mean maternal age was 32.125.37 years range: 1945 years. For women aged 35 years, the mean age was 38.272.66 years, while for those under 35 years, it was 25.984.28 years. No statistically significant differences were observed between the groups in terms of gestational diabetes mellitus, placental abruption, placenta previa, macrosomia, 5th-minute Apgar score, stillbirth, or the need for neonatal intensive care p0.05. However, pregnancy-induced hypertensive disorders, preterm birth, and postpartum hemorrhage PPH were significantly more common in women over 35 years p0.033, p0.039, and p0.043, respectively. Maternal age was identified as a significant positive predictor for preterm birth, PPH, and hypertensive disorders of pregnancy, with preterm birth being the most strongly associated. Receiver operating characteristic ROC analysis revealed optimal maternal age cutoff values for predicting adverse outcomes as follows: 37 years for preterm birth AUC0.687; p0.001 and 33 years for pregnancy-induced hypertensive disorders AUC0.633; p0.006. Conclusion: The risk of pregnancy-induced hypertensive disorders, preterm birth, and PPH increases with maternal age. These findings underscore the need for enhanced antenatal monitoring in women of advanced maternal age.

 Aims: This study aimed to evaluate the impact of advanced maternal age on pregnancy and neonatal outcomes. Methods: In this retrospective study, singleton pregnancies delivered at a tertiary care center between January 2021 and December 2023 were assessed. Participants were divided into two groups based on maternal age at delivery: 1835 years and 35 years. Maternal and perinatal outcomes were compared between the groups using Chi-square tests. Results: The mean maternal age was 32.125.37 years range: 1945 years. For women aged 35 years, the mean age was 38.272.66 years, while for those under 35 years, it was 25.984.28 years. No statistically significant differences were observed between the groups in terms of gestational diabetes mellitus, placental abruption, placenta previa, macrosomia, 5th-minute Apgar score, stillbirth, or the need for neonatal intensive care p0.05. However, pregnancy-induced hypertensive disorders, preterm birth, and postpartum hemorrhage PPH were significantly more common in women over 35 years p0.033, p0.039, and p0.043, respectively. Maternal age was identified as a significant positive predictor for preterm birth, PPH, and hypertensive disorders of pregnancy, with preterm birth being the most strongly associated. Receiver operating characteristic ROC analysis revealed optimal maternal age cutoff values for predicting adverse outcomes as follows: 37 years for preterm birth AUC0.687; p0.001 and 33 years for pregnancy-induced hypertensive disorders AUC0.633; p0.006. Conclusion: The risk of pregnancy-induced hypertensive disorders, preterm birth, and PPH increases with maternal age. These findings underscore the need for enhanced antenatal monitoring in women of advanced maternal age.

 Aims: This study aimed to evaluate the impact of advanced maternal age on pregnancy and neonatal outcomes. Methods: In this retrospective study, singleton pregnancies delivered at a tertiary care center between January 2021 and December 2023 were assessed. Participants were divided into two groups based on maternal age at delivery: 1835 years and 35 years. Maternal and perinatal outcomes were compared between the groups using Chi-square tests. Results: The mean maternal age was 32.125.37 years range: 1945 years. For women aged 35 years, the mean age was 38.272.66 years, while for those under 35 years, it was 25.984.28 years. No statistically significant differences were observed between the groups in terms of gestational diabetes mellitus, placental abruption, placenta previa, macrosomia, 5th-minute Apgar score, stillbirth, or the need for neonatal intensive care p0.05. However, pregnancy-induced hypertensive disorders, preterm birth, and postpartum hemorrhage PPH were significantly more common in women over 35 years p0.033, p0.039, and p0.043, respectively. Maternal age was identified as a significant positive predictor for preterm birth, PPH, and hypertensive disorders of pregnancy, with preterm birth being the most strongly associated. Receiver operating characteristic ROC analysis revealed optimal maternal age cutoff values for predicting adverse outcomes as follows: 37 years for preterm birth AUC0.687; p0.001 and 33 years for pregnancy-induced hypertensive disorders AUC0.633; p0.006. Conclusion: The risk of pregnancy-induced hypertensive disorders, preterm birth, and PPH increases with maternal age. These findings underscore the need for enhanced antenatal monitoring in women of advanced maternal age.

 Aims: This study aimed to evaluate the impact of advanced maternal age on pregnancy and neonatal outcomes. Methods: In this retrospective study, singleton pregnancies delivered at a tertiary care center between January 2021 and December 2023 were assessed. Participants were divided into two groups based on maternal age at delivery: 1835 years and 35 years. Maternal and perinatal outcomes were compared between the groups using Chi-square tests. Results: The mean maternal age was 32.125.37 years range: 1945 years. For women aged 35 years, the mean age was 38.272.66 years, while for those under 35 years, it was 25.984.28 years. No statistically significant differences were observed between the groups in terms of gestational diabetes mellitus, placental abruption, placenta previa, macrosomia, 5th-minute Apgar score, stillbirth, or the need for neonatal intensive care p0.05. However, pregnancy-induced hypertensive disorders, preterm birth, and postpartum hemorrhage PPH were significantly more common in women over 35 years p0.033, p0.039, and p0.043, respectively. Maternal age was identified as a significant positive predictor for preterm birth, PPH, and hypertensive disorders of pregnancy, with preterm birth being the most strongly associated. Receiver operating characteristic ROC analysis revealed optimal maternal age cutoff values for predicting adverse outcomes as follows: 37 years for preterm birth AUC0.687; p0.001 and 33 years for pregnancy-induced hypertensive disorders AUC0.633; p0.006. Conclusion: The risk of pregnancy-induced hypertensive disorders, preterm birth, and PPH increases with maternal age. These findings underscore the need for enhanced antenatal monitoring in women of advanced maternal age.

Article Details

The relationship between advanced maternal age and adverse pregnancy outcomes

Authors:

İsa Temur

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Kadın Hastalıkları ve Doğum

Journal:

Anatolian Current Medical Journal Vol.7 Issue 3, pp.304-310

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001349431

pISSN:

2718-0115

Advanced maternal age

preterm birth

postpartum hemorrhage

pregnancy-induced hypertensive disorders

Issues

Article Details

The relationship between advanced maternal age and adverse pregnancy outcomes

Authors: İsa Temur

Publisher: MediHealth Academy Yayıncılık

Main Topics: Kadın Hastalıkları ve Doğum

Journal: Anatolian Current Medical Journal Vol.7 Issue 3, pp.304-310

Document Type: Article

Publication Date: 5/2025

Document Language: English

Document ID (Org No.): 2001349431

pISSN: 2718-0115

Advanced maternal age

preterm birth

postpartum hemorrhage

pregnancy-induced hypertensive disorders

Issues

Authors:

İsa Temur

Publisher:

MediHealth Academy Yayıncılık

Main Topics:

Kadın Hastalıkları ve Doğum

Journal:

Anatolian Current Medical Journal Vol.7 Issue 3, pp.304-310

Document Type:

Article

Publication Date:

5/2025

Document Language:

English

Document ID (Org No.):

2001349431

pISSN:

2718-0115