Morphometric Changes Due to β Carotene on Wistar Rats Fed Dietary Fat

Getrude N. Okechukwu; Nweke B. Ofobuike; Gabriel G. Akunna; Joseph A. Nwafo; Augustine O. Ibegbu

doi:10.12816/0047907

Article Details

Morphometric Changes Due to β Carotene on Wistar Rats Fed Dietary Fat

Authors:

Getrude N. Okechukwu | Nweke B. Ofobuike | Gabriel G. Akunna | Joseph A. Nwafo | Augustine O. Ibegbu

Publisher:

JOMENAS Press

Main Topics:

Medicine | Zoological sciences/Animals

Journal:

The Journal of Middle East and North Africa Sciences 2018 Vol.4 Issue 6, pp.16-20

Document Type:

Article

Publication Date:

6/2018

Document Language:

English

Document ID (Org No.):

119352

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763

DOI:

10.12816/0047907

Descriptors:

Keywords:

Abstract:

 Beta-carotene (βC), an antioxidant found in fruits and vegetables is responsible for the yellow color of these plants. The aim of the present research was to investigate the morphometric changes on Wistar rats fed high dietary fat and βC. Thirty (30) male Wistar rats were randomly grouped into 6. Group A was the Control and received distilled water, Group B received high-fat diet of 60% fat and 40% rat chow, Group C received 300mg/kg body weight (BW) of βC, Group D received high-fat diet for 12 weeks and was treated with 300mg/kg BW of βC for 2 weeks, Groups E received 300mg/kg BW of βC for 2 weeks and then received high-fat diet for12 weeks while Group F received high-fat diet for 12 weeks and was treated with 150mg/kg BW of βC for 2 weeks. At the end of 16 weeks, the weights, head-tail lengths were measured and the animals humanely sacrificed, the weights of the liver measured. The results showed that increase in high-fat diets did not sequel increase in the body weight and liver weight in the treated groups. When compared to Groups D and F, Group C showed increased body and liver weights but these were lower than that observed in Group A. The liver weight was increased in animals feed dietary fat alone when compared to Group A. The result showed that Lee index was higher in Groups D and F when compared to Groups B and E. The results of the present study suggest that β carotene extract can be very effective in treating weight gain due to high fat diets.
To cite this article
[Okechukwu, G. N., Ofobuike, N. B., Akunna, G. G. Nwafo, J. A. & Ibegbu, A. O. (2018). Morphometric Changes Due To β Carotene on Wistar Rats Fed Dietary Fat. The Journal of Middle East and North Africa Sciences, 4(6), 16-20]. (P-ISSN 2412- 9763) - (e-ISSN 2412-8937). www.jomenas.org.

Article Details

Morphometric Changes Due to β Carotene on Wistar Rats Fed Dietary Fat

Authors:

Getrude N. Okechukwu | Nweke B. Ofobuike | Gabriel G. Akunna | Joseph A. Nwafo | Augustine O. Ibegbu

Publisher:

JOMENAS Press

Main Topics:

Medicine | Zoological sciences/Animals

Journal:

The Journal of Middle East and North Africa Sciences 2018 Vol.4 Issue 6, pp.16-20

Document Type:

Article

Publication Date:

6/2018

Document Language:

English

Document ID (Org No.):

119352

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763

DOI:

10.12816/0047907

Descriptors:

FATS

OVERWEIGHT

WEIGHT GAIN

LIVER

CAROTENOIDS

RATS

LABORATORY ANIMALS

THERAPY

Beta-Carotene

Dietary Fat

Morphometry

Wistar Rats

Body Weight

Liver

Issues

Article Details

Authors: Getrude N. Okechukwu | Nweke B. Ofobuike | Gabriel G. Akunna | Joseph A. Nwafo | Augustine O. Ibegbu

Publisher: JOMENAS Press

Main Topics: Medicine | Zoological sciences/Animals

Journal: The Journal of Middle East and North Africa Sciences 2018 Vol.4 Issue 6, pp.16-20

Document Type: Article

Publication Date: 6/2018

Document Language: English

Document ID (Org No.): 119352

Frequency: Monthly

eISSN: 24128937

pISSN: 24129763

DOI: 10.12816/0047907

Descriptors:

Issues

Authors:

Getrude N. Okechukwu | Nweke B. Ofobuike | Gabriel G. Akunna | Joseph A. Nwafo | Augustine O. Ibegbu

Publisher:

JOMENAS Press

Main Topics:

Medicine | Zoological sciences/Animals

Journal:

The Journal of Middle East and North Africa Sciences 2018 Vol.4 Issue 6, pp.16-20

Document Type:

Article

Publication Date:

6/2018

Document Language:

English

Document ID (Org No.):

119352

Frequency:

Monthly

eISSN:

24128937

pISSN:

24129763

DOI:

10.12816/0047907