Chitosan-drug encapsulation as a potential candidate for COVID-19 drug delivery systems: A review

Onome EJEROMEDOGHENE; Olayinka ODERİNDE; George EGEJURU; Sheriff ADEWUYİ

doi:https://doi.org/10.18596/jotcsa.773780

Article Details

Chitosan-drug encapsulation as a potential candidate for COVID-19 drug delivery systems: A review

Authors:

Onome EJEROMEDOGHENE | Olayinka ODERİNDE | George EGEJURU | Sheriff ADEWUYİ

Publisher:

Turkish Chemical Society

Main Topics:

Chemistry and allied sciences

Journal:

Journal of the Turkish Chemical Society Section A: Chemistry 2020 Vol.7 Issue 3, pp.851-864

Document Type:

Article

Publication Date:

10/2020

Document Language:

English

Document ID (Org No.):

2000502546

Frequency:

Quarterly

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.773780

Abstract:

 

Since the outbreak of COVID-19, the World Health Organization (WHO), Centre for Disease Control (CDC), and other health organizations around the world have coordinated the flow of information and given out preventive directives measures and guidelines to reduce the impact and spread of the disease. Meanwhile, bodies of scientists and researchers around the world are still working ceaselessly to study the virus, mode of transmission mechanisms, and are rapidly developing therapeutic antiviral drugs and vaccines. Thus, the urgent need for the fabrication of biocompatible and biodegradable composite materials as drug delivery vehicles for the efficient loading, targeted delivery and controlled release of antiviral drugs to the target site is been inspired. Therefore, this review highlights the antimicrobial and antiviral activities of chitosan as well as the potency of a combined therapy via electrostatic/hydrogen bonding encapsulation onto the WHO suggested clinical trial drugs and possible chelation with metal ions to form new improved antiviral compounds as a promising agent for the targeted drug delivery.

Article Details

Chitosan-drug encapsulation as a potential candidate for COVID-19 drug delivery systems: A review

Authors: Onome EJEROMEDOGHENE | Olayinka ODERİNDE | George EGEJURU | Sheriff ADEWUYİ

Publisher: Turkish Chemical Society

Main Topics: Chemistry and allied sciences

Journal: Journal of the Turkish Chemical Society Section A: Chemistry 2020 Vol.7 Issue 3, pp.851-864

Document Type: Article

Publication Date: 10/2020

Document Language: English

Document ID (Org No.): 2000502546

Frequency: Quarterly

eISSN: 2149-0120

DOI: https://doi.org/10.18596/jotcsa.773780

Issues

Authors:

Onome EJEROMEDOGHENE | Olayinka ODERİNDE | George EGEJURU | Sheriff ADEWUYİ

Publisher:

Turkish Chemical Society

Main Topics:

Chemistry and allied sciences

Journal:

Journal of the Turkish Chemical Society Section A: Chemistry 2020 Vol.7 Issue 3, pp.851-864

Document Type:

Article

Publication Date:

10/2020

Document Language:

English

Document ID (Org No.):

2000502546

Frequency:

Quarterly

eISSN:

2149-0120

DOI:

https://doi.org/10.18596/jotcsa.773780