Oral Lichen Planus : A Comprehensive Review

Srivastava , Kumar Chandan

doi:10.12816/0057224

Article Details

Oral Lichen Planus : A Comprehensive Review

Authors:

Srivastava , Kumar Chandan

Publisher:

Al Jouf University

Main Topics:

Medicine

Journal:

Aljouf University Medical Journal 2020 Vol.7 Issue 3, pp.1-12

Document Type:

Article

Publication Date:

9/2020

Document Language:

English

Document ID (Org No.):

146492

Frequency:

Quarterly

pISSN:

16586700

DOI:

10.12816/0057224

Descriptors:

Keywords:

Abstract:

 Oral lichen planus (OLP) is a typical chronic lesion perceived as the analogous to cutaneous lichen planus. The global population shows a prevalence of 0.2 - 2%, with variation seen in different ethnic groups. OLP is considered as a result of deregulated immunological phenomena leading to basal cell degeneration and apoptosis of epithelial keratinocytes of oral mucosa. This destruction is mediated by CD8 + cells, possibly triggered by a number of factors such as hepatitis C virus (HCV), drugs and stress. Although OLP has not been established as a predisposing factor for systemic conditions such as diabetes mellitus, hypertension, thyroid diseases and other immunological disturbances, however, literature supports their co-existence. It shows various clinical forms ranging from the most common reticular, to erosive/atrophic, ulcerative/erosive and bullous variant reported the least. Based on the clinical form, it shows a resemblance to leukoplakia, lupus erythematosus and lichenoid reactions. Depending on the severity and location of lesion, corticosteroid remains a mainstay in its treatment. Considering the tendency of erosive OLP form to undergo malignant transformation, makes it important to diagnosis and understand its profile. With a known fact of existing ethnic variation, very few surveys have been done considering OLP among the Saudi Arabian population. Thus, the article aimed to present the most recent update on OLP epidemiology, etiopathogenesis, clinical manifestations and management.

Article Details

Oral Lichen Planus : A Comprehensive Review

Authors:

Srivastava , Kumar Chandan

Publisher:

Al Jouf University

Main Topics:

Medicine

Journal:

Aljouf University Medical Journal 2020 Vol.7 Issue 3, pp.1-12

Document Type:

Article

Publication Date:

9/2020

Document Language:

English

Document ID (Org No.):

146492

Frequency:

Quarterly

pISSN:

16586700

DOI:

10.12816/0057224

Descriptors:

MOUTH DISEASES

DENTISTRY

PATIENTS

SAUDI ARABIA

Oral Lichen Planus

Epidemiology

Corticosteroid Treatment

Malignant Transformation

Prevalence

Saudi Arabia

Issues

Article Details

Authors: Srivastava , Kumar Chandan

Publisher: Al Jouf University

Main Topics: Medicine

Journal: Aljouf University Medical Journal 2020 Vol.7 Issue 3, pp.1-12

Document Type: Article

Publication Date: 9/2020

Document Language: English

Document ID (Org No.): 146492

Frequency: Quarterly

pISSN: 16586700

DOI: 10.12816/0057224

Descriptors:

Issues

Authors:

Srivastava , Kumar Chandan

Publisher:

Al Jouf University

Main Topics:

Medicine

Journal:

Aljouf University Medical Journal 2020 Vol.7 Issue 3, pp.1-12

Document Type:

Article

Publication Date:

9/2020

Document Language:

English

Document ID (Org No.):

146492

Frequency:

Quarterly

pISSN:

16586700

DOI:

10.12816/0057224