Graph Theoretical Analysis of SARS-COV-2 Spike Protein

Akhil C K; Athul T B; Roy John; Manju N. V; Subha A B

doi:10.14419/01r2zb80

Article Details

Graph Theoretical Analysis of SARS-COV-2 Spike Protein

Authors:

Akhil C K | Athul T B | Roy John | Manju N. V | Subha A B

Publisher:

Science Publishing Corporation

Journal:

International Journal of Basic and Applied Sciences Vol.14 Issue 4, pp.194-198

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

2001387322

pISSN:

2227-5053

DOI:

10.14419/01r2zb80

Keywords:

Abstract:

 The spike protein of the severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) is the main surface antigen of the coronavirus. The global pandemic that affected most countries and territories in 2019 was caused by the emergence of the SARS-CoV-2 spike protein. Graph theoretical analysis plays an important role in biological networks. First, we construct the Pt-graph of SARS-CoV-2 based on the physicochemical properties and adjacency of amino acids in the corresponding peptide/protein in SARS-CoV-2. By analyzing the of Pt-graph, we receive some observations about the relations among the amino acids, physiochemical properties of amino acids and peptide/protein, and it will help in the development of and drug design. In this study, we analyze the Pt-graph of the SARS-CoV-2 spike protein to examine its structural properties.

Article Details

Graph Theoretical Analysis of SARS-COV-2 Spike Protein

Authors:

Akhil C K | Athul T B | Roy John | Manju N. V | Subha A B

Publisher:

Science Publishing Corporation

Journal:

International Journal of Basic and Applied Sciences Vol.14 Issue 4, pp.194-198

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

2001387322

pISSN:

2227-5053

DOI:

10.14419/01r2zb80

Amino acid

SARS-CoV-2 spike protein

Graph

Pt-graph

biological networks

Issues

Article Details

Graph Theoretical Analysis of SARS-COV-2 Spike Protein

Authors: Akhil C K | Athul T B | Roy John | Manju N. V | Subha A B

Publisher: Science Publishing Corporation

Journal: International Journal of Basic and Applied Sciences Vol.14 Issue 4, pp.194-198

Document Type: Article

Publication Date: 8/2025

Document Language: English

Document ID (Org No.): 2001387322

pISSN: 2227-5053

DOI: 10.14419/01r2zb80

Amino acid

SARS-CoV-2 spike protein

Graph

Pt-graph

biological networks

Issues

Authors:

Akhil C K | Athul T B | Roy John | Manju N. V | Subha A B

Publisher:

Science Publishing Corporation

Journal:

International Journal of Basic and Applied Sciences Vol.14 Issue 4, pp.194-198

Document Type:

Article

Publication Date:

8/2025

Document Language:

English

Document ID (Org No.):

2001387322

pISSN:

2227-5053

DOI:

10.14419/01r2zb80