EVALUATION OF CONCURRENT ENDOMETRİAL CANCSER İN PATİENTS WİTH ENDOMETRIAL HYPERPLASIA; 10 YEARS EXPERIENCE AS A TERTİARY CENTER

Yusuf ÇAKMAK; Tufan ÖGE; Ece USLU; Duygu KAVAK CÖMERT; Özgür AYDIN TOSUN

doi:https://doi.org/10.16948/zktipb.557389

Article Details

EVALUATION OF CONCURRENT ENDOMETRİAL CANCSER İN PATİENTS WİTH ENDOMETRIAL HYPERPLASIA; 10 YEARS EXPERIENCE AS A TERTİARY CENTER

Authors:

Yusuf ÇAKMAK | Tufan ÖGE | Ece USLU | Duygu KAVAK CÖMERT | Özgür AYDIN TOSUN

Publisher:

Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH

Main Topics:

Promotion of health

Journal:

Medical Bulletin of Zeynep Kamil 2019 Vol.50 Issue 4, pp.222-226

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000757952

Frequency:

Monthly

eISSN:

2148-4864

pISSN:

1300-7971

DOI:

https://doi.org/10.16948/zktipb.557389

Keywords:

Abstract:

 


ABSTRACT


Objective: we aimed to determine the incidence of simultaneous endometrial cancer
in patients with endometrial hyperplasia who underwent surgical treatment.


Material
and method: Our study
was designed retrospectively.The medical data of patients who was
diagnosed  endometrial hyperplasia(EH) by
the endometrial biopsy and accepted surgical treatment  were examined and collected between 2007 -
2017 at the gynecologic oncology depertmant of Eskişehir Osmangazi University(ESOGÜ).
The data of 522 patients with endometrial hyperplasia as a result of endometrial
sampling were evaluated. Due to 187 patients received medical
treatment, 35 patients lacked medical data and 15 patients suspected  endometrial CA were excluded from the study.
A
total of 285 patients with endometrial hyperplasia were included in the study.


Result:
Of the 285 patients included in the study, 64 (22.4%) were simple hyperplasia,
31 (10.8%) were simple atypia hyperplasia, 72 (25.2%) were complex hyperplasia
and 118 (41.4%) were complex atypia hyperplasia. Endometrial
hyperplasia could not be detected in 84 (29.4%) patients after a final
pathology. We found endometrial cancer in 36 (12.6%) patients
and endometrial hyperplasia in 165 (57.8%) patients. We found 1 (1.5%) patient
EC in simple hyperplasia. EC was detected in 1 (3.2%) patient in SAH. 6
patients (8.3%) had EC in CH. 28 (23.7%) EC’s were detected in patients with
CAH. According to the 2014 WHO classification system
,Concurrent endometrial cancer rates were determined as AEH 19.4% and  EH without atypia was 5.1%.











Conclusion: Concurrent EC ratio in simple hyperplasia was
5.1%  this rate was found to be 8.3 % in
CH. Management of patients with endometrial
hyperplasia without atypia If medical treatment is to be chosen, these rates
should be considered and it is recommended to consider all risk factors for EC.


.

 


ÖZET


Amaç: Cerrahi tedavi uygulanan endometrial hiperplazili hastalarda eş
zamanlı endometrial kanser insidansını belirlemeyi amaçladık.


Gereç ve yöntem: Çalışmamız retrospektif olarak dizayn edildi. 2007 - 2017
yılları arasında Eskişehir Osmangazi Üniversitesi (ESOGÜ) jinekolojik Onkoloji
bölümünde endometrial biyopsi ile endometrial hiperplazi (EH) tanısı alan ve
cerrahi tedavi uygulanan hastaların tıbbi kayıtları incelenerek çalışma
oluşturuldu. Endometrial örnekleme sonucu endometrial hiperplazili 522 hastanın
verileri değerlendirildi. 187 hasta medikal tedavi uygulandığı için, 35 hasta
tıbbi kayıtları yetersiz olduğu için  ve
15 hasta endometrial kanser şüphesi olduğu için çalışma dışı bırakıldı.
Çalışmaya endometrial hiperplazili 285 hasta dahil edildi.


Bulgular: Çalışmaya alınan 285 hastanın 64'ü (% 22.4) basit hiperplazi, 31'i (%
10.8) basit atipili hiperplazi, 72'si (% 25.2) kompleks hiperplazi ve 118'i (%
41.4) kompleks atipili hiperplazi idi. Histerektomi spesmenlerinin
incelenmesiyle 84 (% 29.4) hastada endometrial patoloji izlenmezken , 36
hastada (% 12.6) endometrial kanser, 165 hastada (% 57.8) endometrial
hiperplazi bulduk. Basit hiperplazide 1 (% 1,5) hastada endometrial kanser
bulduk.Basit atipili hiperplazide 1 (% 3,2) hastada endometrial kanser tespit
edildi. Kompleks hiperplazide  6 hastada
(% 8.3) endometrial kanser vardı. Kopleks atipili hiperplazide  28 (% 23,7) hastada  endometrial kanser tespit edildi. 2014 Dünya
Sağlık Örgütü sınıflandırma sistemine göre, eş zamanlı endometrial kanser
oranları atipili endometrial hiperplazide  
% 19.4, atipi olmayan endometrial hiperplazide % 5.1 olarak tespit
edildi.


Sonuç:  Basit hiperplazide eşzamanlı
endometrial kanser oranı% 5.1, bu oran kompleks hiperplazide % 8,3 olarak
bulundu. Atipi olmayan endometrial hiperplazili hastaların tedavisinde  medikal tedavi seçilecekse  bu oranlar göz önünde bulundurulmalıdır.Endometrial
hiperplazi yönetiminde  endometrial
kanser için tüm risk faktörlerinin detaylı değerlendirilmesi önerilir.


.

Article Details

EVALUATION OF CONCURRENT ENDOMETRİAL CANCSER İN PATİENTS WİTH ENDOMETRIAL HYPERPLASIA; 10 YEARS EXPERIENCE AS A TERTİARY CENTER

Authors:

Yusuf ÇAKMAK | Tufan ÖGE | Ece USLU | Duygu KAVAK CÖMERT | Özgür AYDIN TOSUN

Publisher:

Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH

Main Topics:

Promotion of health

Journal:

Medical Bulletin of Zeynep Kamil 2019 Vol.50 Issue 4, pp.222-226

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000757952

Frequency:

Monthly

eISSN:

2148-4864

pISSN:

1300-7971

DOI:

https://doi.org/10.16948/zktipb.557389

Atipili endomertial hiperplaziler

Atipisiz endometrial hiperplazi

Endometrial kanser

Issues

Article Details

EVALUATION OF CONCURRENT ENDOMETRİAL CANCSER İN PATİENTS WİTH ENDOMETRIAL HYPERPLASIA; 10 YEARS EXPERIENCE AS A TERTİARY CENTER

Authors: Yusuf ÇAKMAK | Tufan ÖGE | Ece USLU | Duygu KAVAK CÖMERT | Özgür AYDIN TOSUN

Publisher: Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH

Main Topics: Promotion of health

Journal: Medical Bulletin of Zeynep Kamil 2019 Vol.50 Issue 4, pp.222-226

Document Type: Article

Publication Date: 12/2019

Document Language: English

Document ID (Org No.): 2000757952

Frequency: Monthly

eISSN: 2148-4864

pISSN: 1300-7971

DOI: https://doi.org/10.16948/zktipb.557389

Atipili endomertial hiperplaziler

Atipisiz endometrial hiperplazi

Endometrial kanser

Issues

Authors:

Yusuf ÇAKMAK | Tufan ÖGE | Ece USLU | Duygu KAVAK CÖMERT | Özgür AYDIN TOSUN

Publisher:

Zeynep Kamil Kadın ve Çocuk Hastalıkları EAH

Main Topics:

Promotion of health

Journal:

Medical Bulletin of Zeynep Kamil 2019 Vol.50 Issue 4, pp.222-226

Document Type:

Article

Publication Date:

12/2019

Document Language:

English

Document ID (Org No.):

2000757952

Frequency:

Monthly

eISSN:

2148-4864

pISSN:

1300-7971

DOI:

https://doi.org/10.16948/zktipb.557389