Does Migraine Attack Cause Cognitive Impairment and White Matter Lesions?

N.A.

Article Details

Does Migraine Attack Cause Cognitive Impairment and White Matter Lesions?

Authors:

N.A.

Publisher:

Ankara University

Main Topics:

Brain and Nerve Surgery (Neurosurgery) | Neurology and Neuromuscular Diseases

Journal:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.238-243

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001349852

pISSN:

0365-8104

Keywords:

Abstract:

 Objectives: The aim of the study is to better assess the association between cognitive impairment during migraine attacks and white matter lesions, in conjunction with the relation of anatomical localizations in migraineurs with white matter lesions. Materials and Methods: Study questionnaires were filled during routine medical visitations. In the context of cognitive functions evaluation, the standardized mini-mental status examination was utilized. Patient demographics and migraine characteristics were carefully recorded. The Migraine Disability Assessment Score, the Headache Impact Test, and the Mig-SCog questionnaires were used to test the ultimate severity of the migraine. Brain magnetic resonance imaging MRI scans were evaluated with the benefit of hindsight; for detecting and scoring white matter lesions, the Scheltens scoring system was brought into play. Depending upon perceived presence or absence of hyperintense lesions in brain MRI, the patients were divided into a pair of specific subsections. Results: One hundred twenty female 86 and 19 14 male patients were evaluated, respectively. Statistically significant differences were uncovered between the two groupings related to their intrinsic demographics, age, and educational levels. Patients demonstrating normal MRI had shorter disease duration when juxtaposed with the grouping possessed of white matter lesions. As per Mig-SCog questionnaires, cognitive complaints during migraine attacks were statistically significant within the tranche with white matter lesions. Interestingly, longer durations of migraine and higher Mig-SCog scores were correlated with deep white matter hyperintensities. Conclusion: During instances of migraine attack, the underlying migraine pathophysiological process can significantly influence cognitive impairment and noticeable alterations to white matter. Key Words: Migraine, Cognition, White Matter.

 Objectives: The aim of the study is to better assess the association between cognitive impairment during migraine attacks and white matter lesions, in conjunction with the relation of anatomical localizations in migraineurs with white matter lesions. Materials and Methods: Study questionnaires were filled during routine medical visitations. In the context of cognitive functions evaluation, the standardized mini-mental status examination was utilized. Patient demographics and migraine characteristics were carefully recorded. The Migraine Disability Assessment Score, the Headache Impact Test, and the Mig-SCog questionnaires were used to test the ultimate severity of the migraine. Brain magnetic resonance imaging MRI scans were evaluated with the benefit of hindsight; for detecting and scoring white matter lesions, the Scheltens scoring system was brought into play. Depending upon perceived presence or absence of hyperintense lesions in brain MRI, the patients were divided into a pair of specific subsections. Results: One hundred twenty female 86 and 19 14 male patients were evaluated, respectively. Statistically significant differences were uncovered between the two groupings related to their intrinsic demographics, age, and educational levels. Patients demonstrating normal MRI had shorter disease duration when juxtaposed with the grouping possessed of white matter lesions. As per Mig-SCog questionnaires, cognitive complaints during migraine attacks were statistically significant within the tranche with white matter lesions. Interestingly, longer durations of migraine and higher Mig-SCog scores were correlated with deep white matter hyperintensities. Conclusion: During instances of migraine attack, the underlying migraine pathophysiological process can significantly influence cognitive impairment and noticeable alterations to white matter. Key Words: Migraine, Cognition, White Matter.

 Objectives: The aim of the study is to better assess the association between cognitive impairment during migraine attacks and white matter lesions, in conjunction with the relation of anatomical localizations in migraineurs with white matter lesions. Materials and Methods: Study questionnaires were filled during routine medical visitations. In the context of cognitive functions evaluation, the standardized mini-mental status examination was utilized. Patient demographics and migraine characteristics were carefully recorded. The Migraine Disability Assessment Score, the Headache Impact Test, and the Mig-SCog questionnaires were used to test the ultimate severity of the migraine. Brain magnetic resonance imaging MRI scans were evaluated with the benefit of hindsight; for detecting and scoring white matter lesions, the Scheltens scoring system was brought into play. Depending upon perceived presence or absence of hyperintense lesions in brain MRI, the patients were divided into a pair of specific subsections. Results: One hundred twenty female 86 and 19 14 male patients were evaluated, respectively. Statistically significant differences were uncovered between the two groupings related to their intrinsic demographics, age, and educational levels. Patients demonstrating normal MRI had shorter disease duration when juxtaposed with the grouping possessed of white matter lesions. As per Mig-SCog questionnaires, cognitive complaints during migraine attacks were statistically significant within the tranche with white matter lesions. Interestingly, longer durations of migraine and higher Mig-SCog scores were correlated with deep white matter hyperintensities. Conclusion: During instances of migraine attack, the underlying migraine pathophysiological process can significantly influence cognitive impairment and noticeable alterations to white matter. Key Words: Migraine, Cognition, White Matter.

 Amaç: Çalışmanın amacı migren atağı sırasındaki kognitif bozulma ile beyaz cevher lezyonları arasındaki ilişkinin yanı sıra migrenin, beyaz cevher lezyonlarının anatomik lokalizasyonları ile ilişkisini ortaya koymaktır. Gereç ve Yöntem: Çalışma anketleri rutin muayene sırasında dolduruldu. Kognitif işlevleri değerlendirilmek için standartize mini-mental durum muayenesinden yararlanıldı. Hastaların demografik özellikleri ve migren özellikleri kaydedildi. Migrenin şiddetini test etmek için Migraine Disability Assessment Score, Headache Impact Test, ve Mig-Scog anketleri kullanıldı. Beyin manyetik rezonans görüntülemeleri MRG değerlendirildi; Beyaz cevher lezyonlarının tespiti ve skorlanması için Scheltens skorlama sistemi kullanıldı. Beyin MRGsinde hiperintens lezyonların varlığına veya yokluğuna bağlı olarak hastalar iki alt gruba ayrıldı. Bulgular: Yüz yirmi kadın 86 ve 19 14 erkek hasta değerlendirildi. İki grup arasında demografik özellikler, yaş ve eğitim düzeylerine ilişkin istatistiksel olarak anlamlı farklılıklar ortaya çıktı. MRGi normal olan hastaların hastalık süresi, beyaz cevher lezyonlarının olduğu grupla karşılaştırıldığında daha kısaydı. Mig-SCog anketlerine göre migren atakları sırasındaki bilişsel yakınmalar beyaz cevher lezyonları olan grupta istatistiksel olarak anlamlıydı. Migren süreleri daha uzun olan ve daha yüksek Mig-SCog skorları, derin beyaz cevher hiperintensiteleri ile koreleydi. Sonuç: Migren atakları sırasında, altında yatan patofizyolojik süreç kognitif bozulmaya ve beyaz cevher değişikliklerine neden olabilir. Anahtar Kelimeler: Migren, Kognisyon, Beyaz Cevher.

Article Details

Does Migraine Attack Cause Cognitive Impairment and White Matter Lesions?

Authors:

N.A.

Publisher:

Ankara University

Main Topics:

Brain and Nerve Surgery (Neurosurgery) | Neurology and Neuromuscular Diseases

Journal:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.238-243

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001349852

pISSN:

0365-8104

Migraine

Cognition

White MatterMigren

Kognisyon

Beyaz Cevher

Issues

Article Details

Does Migraine Attack Cause Cognitive Impairment and White Matter Lesions?

Authors: N.A.

Publisher: Ankara University

Main Topics: Brain and Nerve Surgery (Neurosurgery) | Neurology and Neuromuscular Diseases

Journal: Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.238-243

Document Type: Article

Publication Date: 10/2023

Document Language: English

Document ID (Org No.): 2001349852

pISSN: 0365-8104

Migraine

Cognition

White MatterMigren

Kognisyon

Beyaz Cevher

Issues

Authors:

N.A.

Publisher:

Ankara University

Main Topics:

Brain and Nerve Surgery (Neurosurgery) | Neurology and Neuromuscular Diseases

Journal:

Ankara Üniversitesi Tıp Fakültesi Mecmuası Vol.76 Issue 3, pp.238-243

Document Type:

Article

Publication Date:

10/2023

Document Language:

English

Document ID (Org No.):

2001349852

pISSN:

0365-8104