Effect of hydroalcoholic leaves extract of Datura stramonium on pathogenic Candida albicans: Ali Y. Salman and Mohammed K. Faraj

Ali Y. Salman

doi:10.30539/iraqijvm.v39i2.178

Article Details

Effect of hydroalcoholic leaves extract of Datura stramonium on pathogenic Candida albicans: Ali Y. Salman and Mohammed K. Faraj

Authors:

Ali Y. Salman

Publisher:

University of Baghdad

Journal:

The Iraqi Journal of Veterinary Medicine Vol.39 Issue 2, pp.55-61

Document Type:

Article

Publication Date:

12/2015

Document Language:

English

Document ID (Org No.):

2001376355

pISSN:

2410-7409

DOI:

10.30539/iraqijvm.v39i2.178

Keywords:

Abstract:

  This research aimed at studying the effect of different concentration of hydroalcoholic leaves extract of Datura stramonium concentration against pathogenic Candida albicans isolated from clinical cases of diarrhea in cows and dogs in Baghdad province. Hydroalcoholic extract of the leaves of Datura stramonium were prepared in different concentrations for In vitro and In vivo study against Candida albicans. In vitro test includes the determination of minimum inhibitory concentration 50, 25, 12.5, 6.25, 3.12 and 1.75mg/1ml), and it was found that the minimum inhibitory concentration was 3.12 mg/1ml. Whereas the in vivo test was performed for the determination of sensitivity test of Candida albicans in concentration of plant 10, 15 and 20 mg/1ml which was compared with same concentration of Nystatin. The study was performed in seven groups of mice according to different concentrations. The infective dose of Candida albicans was 1X108, which was proved by histopathology changes after eight day. The result obtained from invivo study revealed that after the end of the therapeutic period that lasted for 8 days. Confirm the efficacy of Datura stramonium extract at 20% as a treatment for mice infected with Candida albicans.

Article Details

Effect of hydroalcoholic leaves extract of Datura stramonium on pathogenic Candida albicans: Ali Y. Salman and Mohammed K. Faraj

Authors:

Ali Y. Salman

Publisher:

University of Baghdad

Journal:

The Iraqi Journal of Veterinary Medicine Vol.39 Issue 2, pp.55-61

Document Type:

Article

Publication Date:

12/2015

Document Language:

English

Document ID (Org No.):

2001376355

pISSN:

2410-7409

DOI:

10.30539/iraqijvm.v39i2.178

Datura stramonium

Candida albicans

Hydroalcoholic extract

White mice

Issues

Article Details

Effect of hydroalcoholic leaves extract of Datura stramonium on pathogenic Candida albicans: Ali Y. Salman and Mohammed K. Faraj

Authors: Ali Y. Salman

Publisher: University of Baghdad

Journal: The Iraqi Journal of Veterinary Medicine Vol.39 Issue 2, pp.55-61

Document Type: Article

Publication Date: 12/2015

Document Language: English

Document ID (Org No.): 2001376355

pISSN: 2410-7409

DOI: 10.30539/iraqijvm.v39i2.178

Datura stramonium

Candida albicans

Hydroalcoholic extract

White mice

Issues

Authors:

Ali Y. Salman

Publisher:

University of Baghdad

Journal:

The Iraqi Journal of Veterinary Medicine Vol.39 Issue 2, pp.55-61

Document Type:

Article

Publication Date:

12/2015

Document Language:

English

Document ID (Org No.):

2001376355

pISSN:

2410-7409

DOI:

10.30539/iraqijvm.v39i2.178