Comparison of Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery in Two Groups Taking Aspirin and Aspirin plus CLS Clopidogrel

Ali Pooria; Hassan Teimouri; Mostafa Cheraghi; Babak Baharvand Ahmadi; Mehrdad Namdari; Reza Alipoor

doi:10.5742/MEWFM.2017.93050

Article Details

Comparison of Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery in Two Groups Taking Aspirin and Aspirin plus CLS Clopidogrel

Authors:

Ali Pooria | Hassan Teimouri | Mostafa Cheraghi | Babak Baharvand Ahmadi | Mehrdad Namdari | Reza Alipoor

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 8, pp.17-23

Document Type:

Article

Publication Date:

10/2017

Document Language:

English

Document ID (Org No.):

109479

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93050

Descriptors:

Keywords:

Abstract:

 Introduction: Coronary Artery Bypass Grafting(CABG) is a surgical procedure that aims to easesymptoms and reduce the risk of death in patientswith coronary artery occlusion. In this surgery,healthy blood vessels from other parts of the bodyreplace occluded coronary arteries. This surgeryis done to improve blood supply to the heart. Becauseof its invasive nature, this procedure is associatedwith complications including postoperativebleeding.Methods: The study included 68 subjects in eachgroup. The inclusion criteria were age of 40-80years, serum creatinine under 1.5 mg/dl, plateletcount above 100 thousand per microliter, hemoglobinabove 8 g per deciliter, and normal PTand PTT. The patients underwent the procedurethrough the on-pump method. The study populationincluded the patients undergoing CABGin Khorramabad Heart Hospital. The convenience,consecutive sampling method was applied,based on the inclusion criteria of the study.Results: The mean age of the patients treated withaspirin was 60.9 ± 11.05, and the mean age of thepatients treated with aspirin plus clopidogrel was60.48 ± 9.8 years. The mean FFP intake in the aspirinplus clopidogrel group during hospitalizationwas significantly higher than the mean in the aspiringroup (PV= 0.0009). The mean cell pack intake in theaspirin plus clopidogrel group during hospitalizationwas higher than the mean in the aspirin group, but thisdifference was not statistically significant (PV=0.068)Discussion: The rate of postoperative bleeding inthe clopidogrel plus aspirin group was higher thanthe rate in the aspirin group, but this difference wasnot significant (PV=0.067). The rate of Hb, HCT,and platelets in the aspirin plus clopidogrel groupat discharge was higher than the rate in the aspiringroup, which was due to excess bleeding inthe aspirin plus clopidogrel group compared to theaspirin group. The rate of FFP intake in the aspirinplus clopidogrel group was significantly higherthan the rate in the aspirin group, which was due toexcess bleeding in the aspirin plus clopidogrelgroup (PV=0.0009).

Article Details

Comparison of Postoperative Bleeding in Patients Undergoing Coronary Artery Bypass Surgery in Two Groups Taking Aspirin and Aspirin plus CLS Clopidogrel

Authors:

Ali Pooria | Hassan Teimouri | Mostafa Cheraghi | Babak Baharvand Ahmadi | Mehrdad Namdari | Reza Alipoor

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 8, pp.17-23

Document Type:

Article

Publication Date:

10/2017

Document Language:

English

Document ID (Org No.):

109479

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93050

Descriptors:

CORONARY ARTERIES

CORONARY HEART DISEASES

SURGICAL OPERATIONS

BLEEDING

DRUGS

PATIENTS

HOSPITALS

IRAN

Coronary Artery Bypass Grafting

Aspirin

Clopidogrel

Issues

Article Details

Authors: Ali Pooria | Hassan Teimouri | Mostafa Cheraghi | Babak Baharvand Ahmadi | Mehrdad Namdari | Reza Alipoor

Publisher: medi+WORLD International

Main Topics: Medicine

Journal: World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 8, pp.17-23

Document Type: Article

Publication Date: 10/2017

Document Language: English

Document ID (Org No.): 109479

Frequency: Monthly

eISSN: 18390196

pISSN: 18390188

DOI: 10.5742/MEWFM.2017.93050

Descriptors:

Issues

Authors:

Ali Pooria | Hassan Teimouri | Mostafa Cheraghi | Babak Baharvand Ahmadi | Mehrdad Namdari | Reza Alipoor

Publisher:

medi+WORLD International

Main Topics:

Medicine

Journal:

World Family Medicine Journal: Incorporating the Middle East Journal of Family Medicine 2017 Vol.15 Issue 8, pp.17-23

Document Type:

Article

Publication Date:

10/2017

Document Language:

English

Document ID (Org No.):

109479

Frequency:

Monthly

eISSN:

18390196

pISSN:

18390188

DOI:

10.5742/MEWFM.2017.93050